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Acap3 Gene Detail
Summary
  • Symbol
    Acap3
  • Name
    ArfGAP with coiled-coil, ankyrin repeat and PH domains 3
  • Synonyms
    Centb5, Kiaa1716-hp, mKIAA1716
  • Feature Type
    protein coding gene
  • IDs
    MGI:2153589
    NCBI Gene: 140500
  • Alliance
    gene page
  • Transcription Start Sites
    5 TSS
Location &
Maps
more
  • Sequence Map
    Chr4:155976332-155991708 bp, + strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 4, 87.66 cM
  • Mapping Data
    1 experiment
Strain
Comparison
more
  • SNPs within 2kb
    529 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_2153589
 protein coding gene Chr4:155976279-155991708 (+)
129S1/SvImJ MGP_129S1SvImJ_G0029238
 protein coding gene Chr4:160264603-160282866 (+)
A/J MGP_AJ_G0029203
 protein coding gene Chr4:153511031-153526930 (+)
AKR/J MGP_AKRJ_G0029151
 protein coding gene Chr4:157689042-157703761 (+)
BALB/cJ MGP_BALBcJ_G0029219
 protein coding gene Chr4:153984152-153998823 (+)
C3H/HeJ MGP_C3HHeJ_G0028940
 protein coding gene Chr4:158231756-158246547 (+)
C57BL/6NJ MGP_C57BL6NJ_G0029668
 protein coding gene Chr4:165942142-165956803 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0026912
 protein coding gene Chr4:145798090-145812906 (+)
CAST/EiJ MGP_CASTEiJ_G0028352
 protein coding gene Chr4:155702607-155717881 (+)
CBA/J MGP_CBAJ_G0028902
 protein coding gene Chr4:170958785-170973552 (+)
DBA/2J MGP_DBA2J_G0029051
 protein coding gene Chr4:153532224-153549219 (+)
FVB/NJ MGP_FVBNJ_G0029014
 protein coding gene Chr4:152782850-152797548 (+)
LP/J MGP_LPJ_G0029141
 protein coding gene Chr4:160194379-160220855 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0029041
 protein coding gene Chr4:173768210-173784911 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0029700
 protein coding gene Chr4:158321678-158336966 (+)
PWK/PhJ MGP_PWKPhJ_G0028073
 protein coding gene Chr4:149675183-149690938 (+)
SPRET/EiJ MGP_SPRETEiJ_G0027907
 protein coding gene Chr4:152577526-152592086 (+)
WSB/EiJ MGP_WSBEiJ_G0028432
 protein coding gene Chr4:158491933-158506658 (+)



Homology
more
  • Human Ortholog
    ACAP3, ArfGAP with coiled-coil, ankyrin repeat and PH domains 3
  • Vertebrate Orthologs
    4
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    ACAP3, ArfGAP with coiled-coil, ankyrin repeat and PH domains 3
  • Synonyms
    CENTB5
  • Links
    NCBI Gene ID: 116983
    neXtProt AC: NX_Q96P50
    UniProt: Q96P50

  • Chr Location
    1p36.33; chr1:1292390-1309609 (-)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    1 phenotype from 1 allele in 1 genetic background
    6 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    4
  • GO References
    2
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    741
  • Tissues
    23
  • cDNA Data
    56
  • Literature Summary
    2
  • Comparison Matrix
    Gene Expression + Phenotype
    • Sequences &
    Gene Models
    less
    Representative SequencesLengthStrain/SpeciesFlank
    genomic 140500 NCBI Gene Model | MGI Sequence Detail 15377 C57BL/6J ±  kb
    transcript NM_207223 RefSeq | MGI Sequence Detail 4438 ZRU/MplStud  
    polypeptide NP_997106 RefSeq | MGI Sequence Detail 833 ZRU/MplStud  
    For the selected sequence
    Protein
    Information
    less
    Molecular
    Reagents
    less
    • All nucleic 59
      Genomic 1
      cDNA 56
      Primer pair 1
      Other 1

      Microarray probesets 3
    References
    more
    • Summaries
      All 27
      Developmental Gene Expression 2
      Gene Ontology 2
      Phenotypes 6
    • Earliest
      J:72149 Bachmanov AA, et al., Positional cloning of the mouse saccharin preference (Sac) locus. Chem Senses. 2001 Sep;26(7):925-33
    • Latest
      J:345621 Adams DJ, et al., Genetic determinants of micronucleus formation in vivo. Nature. 2024 Mar;627(8002):130-136
    Contributing Projects:
    Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
    Citing These Resources
    Funding Information
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    Send questions and comments to User Support.     		last database update
    12/17/2024
    MGI 6.24     		The Jackson Laboratory