Col26a1 MGI Mouse Gene Detail - MGI:2155345 - collagen, type XXVI, alpha 1

Symbol

Col26a1
Name

collagen, type XXVI, alpha 1
Synonyms

9430032K24Rik, Collagen XXVI, Emid2, Emu2, MGC:7475

Feature Type

protein coding gene
IDs

MGI:2155345
NCBI Gene: 140709
Alliance

gene page
Transcription Start Sites

6 TSS

Sequence Map

Chr5:136770613-136912063 bp, - strand
From Ensembl annotation of GRCm39
View this region in JBrowse
Genome Browsers

Ensembl | UCSC | NCBI

Genetic Map

Chromosome 5, 76.03 cM, cytoband G1
Mapping Data

3 experiments

SNPs within 2kb

4814 from dbSNP Build 142
Strain Annotations

18

For selected strains:

Strain	Gene Model ID	Feature Type	Coordinates
C57BL/6J	MGI_C57BL6J_2155345	protein coding gene	Chr5:136770613-136912230 (-)
129S1/SvImJ	MGP_129S1SvImJ_G0030208	protein coding gene	Chr5:141415373-141575953 (-)
A/J	MGP_AJ_G0030176	protein coding gene	Chr5:135304619-135452089 (-)
AKR/J	MGP_AKRJ_G0030109	protein coding gene	Chr5:139682123-139829710 (-)
BALB/cJ	MGP_BALBcJ_G0030186	protein coding gene	Chr5:136661469-136811403 (-)
C3H/HeJ	MGP_C3HHeJ_G0029902	protein coding gene	Chr5:140294550-140458134 (-)
C57BL/6NJ	MGP_C57BL6NJ_G0030638	protein coding gene	Chr5:146675362-146835541 (-)
CAROLI/EiJ	MGP_CAROLIEiJ_G0027859	protein coding gene	Chr5:129583004-129725280 (-)
CAST/EiJ	MGP_CASTEiJ_G0029312	protein coding gene	Chr5:139704226-139876809 (-)
CBA/J	MGP_CBAJ_G0029872	protein coding gene	Chr5:152365014-152569345 (-)
DBA/2J	MGP_DBA2J_G0030023	protein coding gene	Chr5:135201421-135347978 (-)
FVB/NJ	MGP_FVBNJ_G0029978	protein coding gene	Chr5:134373600-134524104 (-)
LP/J	MGP_LPJ_G0030112	protein coding gene	Chr5:141836746-142012673 (-)
NOD/ShiLtJ	MGP_NODShiLtJ_G0030010	protein coding gene	Chr5:155318956-155494694 (-)
NZO/HlLtJ	MGP_NZOHlLtJ_G0030679	protein coding gene	Chr5:139500330-139661102 (-)
PWK/PhJ	MGP_PWKPhJ_G0029025	protein coding gene	Chr5:134284734-134431628 (-)
SPRET/EiJ	MGP_SPRETEiJ_G0028861	protein coding gene	Chr5:137086718-137249893 (-)
WSB/EiJ	MGP_WSBEiJ_G0029385	protein coding gene	Chr5:140237900-140401143 (-)

Human Ortholog

COL26A1, collagen type XXVI alpha 1 chain

Vertebrate Orthologs

2

Vertebrate Orthology Source

Alliance of Genome Resources

Human Ortholog

COL26A1, collagen type XXVI alpha 1 chain
Synonyms

EMI6, EMID2, EMU2, SH2B
Links

HGNC:18038

NCBI Gene ID: 136227

neXtProt AC: NX_Q96A83

UniProt: Q96A83
Chr Location

7q22.1; chr7:101362388-101559024 (+) GRCh38

MGI Vertebrate Homology

Col26a1 stringent orthology
1 human;1 mouse;1 rat
HCOP

vertebrate homology predictions: COL26A1
Gene Tree

Col26a1

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Phenotype Summary

3 phenotypes from 1 allele in 1 genetic background
9 phenotype references

Phenotype Overview

Blue squares indicate phenotypes directly attributed to mutations/alleles of this gene.

adipose tissue	behavior/neurological	cardiovascular system	cellular	craniofacial	digestive/alimentary system	embryo	endocrine/exocrine glands	growth/size/body	hearing/vestibular/ear	hematopoietic system	homeostasis/metabolism	integument	immune system	limbs/digits/tail	liver/biliary system	mortality/aging	muscle	nervous system	pigmentation	renal/urinary system	reproductive system	respiratory system	skeleton	taste/olfaction	neoplasm	vision/eye

Click cells to view annotations.

All Mutations and Alleles

9
Endonuclease-mediated

6
Gene trapped

1
Targeted

2
Incidental Mutations

APF , CvDC
Find Mice (IMSR)

31 strains or lines available
Comparison Matrix

Gene Expression + Phenotype

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All GO Annotations

8
GO References

3

Molecular Function

carbohydrate derivative binding	cytoskeletal protein binding	DNA binding	enzyme regulator	hydrolase	ligase	lipid binding	oxidoreductase	RNA binding	signaling receptor activity	signaling receptor binding	transcription	transferase	transporter

Biological Process

carbohydrate derivative metabolism	cell differentiation	cell population proliferation	cellular component organization	DNA-templated transcription	establishment of localization	homeostatic process	immune system process	lipid metabolic process	programmed cell death	protein metabolic process	response to stimulus	signaling	system development

Cellular Component

cell projection	cytoplasmic vesicle	cytoskeleton	cytosol	endoplasmic reticulum	endosome	extracellular region	Golgi apparatus	mitochondrion	membraneless organelle	nucleus	organelle envelope	organelle lumen	plasma membrane	protein-containing complex	synapse	vacuole

Click cells to view annotations.

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Expression Overview

GXD's primary emphasis is on endogenous gene expression during development. Click on grid cells to view annotations.

Blue cells = expressed in wild-type.
Gray triangles = other expression annotations only
(e.g. absence of expression or data from mutants).

early conceptus	embryo ectoderm	embryo endoderm	embryo mesoderm	embryo mesenchyme	extraembryonic component	alimentary system	auditory system	branchial arches	cardiovascular system	connective tissue	endocrine system	exocrine system	hemolymphoid system	integumental system	limbs	liver and biliary system	musculoskeletal system	nervous system	olfactory system	reproductive system	respiratory system	urinary system	visual system

Click cells to view annotations.

Assay Results

964
Tissues

16
cDNA Data

53
Literature Summary

7

Images

Tissue x Stage Matrix

Comparison Matrix

Gene Expression + Phenotype

Other Mouse Links

Allen Institute

GEO

Expression Atlas
Other Vertebrate Links

GEISHA COL26A1

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All Sequences

66
RefSeq

20
UniProt

2
CCDS

CCDS19755.1, CCDS84976.1

Ensembl

ENSMUSG00000004415 (Evidence)
NCBI Gene

140709

			Length	Strain/Species	Flank
genomic	ENSMUSG00000004415	Ensembl Gene Model \| MGI Sequence Detail	141451	C57BL/6J	± kb
transcript	ENSMUST00000057497	Ensembl \| MGI Sequence Detail	2724	Not Applicable
polypeptide	ENSMUSP00000052095	Ensembl \| MGI Sequence Detail	440	Not Applicable

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UniProt

2 Sequences
Protein Ontology

PR:000007052 collagen alpha-1(XXVI) chain

(term hierarchy)
InterPro Domains

IPR050392 Collagen/C1q domain-containing

IPR008160 Collagen triple helix repeat

IPR011489 EMI domain
GlyGen

Q91VF6 2 sites, 1 N-linked glycan (1 site)

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All nucleic 54

cDNA 53

Primer pair 1

Microarray probesets 3

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MGI:1924594, MGI:1933106, MGI:2653242

Summaries

All 44

Developmental Gene Expression 7

Gene Ontology 3

Phenotypes 9
Earliest

J:7899 Sutton VR, et al., Identification of two forms of the Ly-6.2 antigen showing differential expression. Immunogenetics. 1985;21(6):539-47
Latest

J:345621 Adams DJ, et al., Genetic determinants of micronucleus formation in vivo. Nature. 2024 Mar;627(8002):130-136

TSS for Col26a1:

(View these features in JBrowse)

Transcription Start Site	Location	Distance from Gene 5'-end
Tssr53876	Chr5:136912074-136912086 (-)	-17 bp
Tssr53875	Chr5:136912057-136912068 (-)	0 bp
Tssr53874	Chr5:136911969-136912022 (-)	67 bp
Tssr1676	Chr5:136911949-136911955 (-)	111 bp
Tssr53873	Chr5:136911931-136911947 (-)	124 bp
Tssr53871	Chr5:136841393-136841394 (-)	70,669 bp

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources Funding Information Warranty Disclaimer, Privacy Notice, Licensing, & Copyright Send questions and comments to User Support.	last database update 12/10/2024 MGI 6.24