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Caln1 Gene Detail
Summary
  • Symbol
    Caln1
  • Name
    calneuron 1
  • Synonyms
    9630012C17Rik, Cabp8
  • Feature Type
    protein coding gene
  • IDs
    MGI:2155987
    NCBI Gene: 140904
  • Alliance
  • Transcription Start Sites
    16 TSS
Location &
Maps
more
  • Sequence Map
    Chr5:130398296-130876253 bp, + strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
  • Genetic Map
    Chromosome 5, 69.29 cM, cytoband F
  • Mapping Data
    3 experiments
Strain
Comparison
more
  • SNPs within 2kb
    14300 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_2155987
protein coding gene Chr5:130398245-130876253 (+)
129S1/SvImJ MGP_129S1SvImJ_G0030146
protein coding gene Chr5:134512707-135045705 (+)
A/J MGP_AJ_G0030114
protein coding gene Chr5:128829121-129318135 (+)
AKR/J MGP_AKRJ_G0030047
protein coding gene Chr5:133011107-133516067 (+)
BALB/cJ MGP_BALBcJ_G0030124
protein coding gene Chr5:130183359-130664598 (+)
C3H/HeJ MGP_C3HHeJ_G0029840
protein coding gene Chr5:133578861-134090193 (+)
C57BL/6NJ MGP_C57BL6NJ_G0030577
protein coding gene Chr5:139661281-140189439 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0027802
protein coding gene Chr5:123208483-123686408 (+)
CAST/EiJ MGP_CASTEiJ_G0029250
protein coding gene Chr5:132907520-133430744 (+)
CBA/J MGP_CBAJ_G0029810
protein coding gene Chr5:145095680-145687893 (+)
DBA/2J MGP_DBA2J_G0029961
protein coding gene Chr5:128792742-129274067 (+)
FVB/NJ MGP_FVBNJ_G0029916
protein coding gene Chr5:127885619-128374442 (+)
LP/J MGP_LPJ_G0030049
protein coding gene Chr5:135016854-135550168 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0029948
protein coding gene Chr5:148422968-148949379 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0030617
protein coding gene Chr5:132705407-133227025 (+)
PWK/PhJ MGP_PWKPhJ_G0028964
protein coding gene Chr5:127735542-128246861 (+)
SPRET/EiJ MGP_SPRETEiJ_G0028800
protein coding gene Chr5:130283020-130814104 (+)
WSB/EiJ MGP_WSBEiJ_G0029323
protein coding gene Chr5:133422749-133939195 (+)



Homology
more
  • Human Ortholog
    CALN1, calneuron 1
  • Vertebrate Orthologs
    4
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    CALN1, calneuron 1
  • Synonyms
    CABP8
  • Links
    NCBI Gene ID: 83698
    neXtProt AC: NX_Q9BXU9
    UniProt: Q9BXU9

  • Chr Location
    7q11.22; chr7:71779491-72504279 (-)  GRCh38

Mutations,
Alleles, and
Phenotypes
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  • Phenotype Summary
    9 phenotypes from 1 allele in 1 genetic background
    2 phenotypes from multigenic genotypes
    10 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Mice homozygous for a null allele exhibit fewer Golgi satellites and decreased levels of polysialylation of NCAM in distal dendrites of hippocampal CA1 neurons that receive input from the temporoammonic pathway and reduced long-term potentiation at distal synapses.
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

No experimental evidence to support Biological Process annotation, following literature review. See J:73796.
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
  • Comparison Matrix
  • Sequences &
    Gene Models
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    Representative SequencesLengthStrain/SpeciesFlank
    genomic ENSMUSG00000060371 Ensembl Gene Model | MGI Sequence Detail 477958 C57BL/6J ±  kb
    transcript ENSMUST00000086029 Ensembl | MGI Sequence Detail 1801 Not Applicable  
    polypeptide ENSMUSP00000083193 Ensembl | MGI Sequence Detail 261 Not Applicable  
    For the selected sequence
    Protein
    Information
    less
    Molecular
    Reagents
    less
    • All nucleic 13
      cDNA 13

      Microarray probesets 3
    Other
    Accession IDs
    less
    MGI:2444767
    References
    more
    • Summaries
      All 38
      Developmental Gene Expression 3
      Gene Ontology 6
      Phenotypes 10
    • Earliest
      J:134667 Roderick TH, et al., Two radiation-induced chromosomal inversions in mice (Mus musculus). Proc Natl Acad Sci U S A. 1970 Oct;67(2):961-7
    • Latest
      J:338143 Andres-Alonso M, et al., Golgi satellites are essential for polysialylation of NCAM and expression of LTP at distal synapses. Cell Rep. 2023 Jun 23;42(7):112692

    Contributing Projects:
    Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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    Funding Information
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    last database update
    12/10/2024
    MGI 6.24
    The Jackson Laboratory