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Rnf39 Gene Detail
Summary
  • Symbol
    Rnf39
  • Name
    ring finger protein 39
  • Synonyms
    LIRF, LOC240094, LOC386454, LOC386465
  • Feature Type
    protein coding gene
  • IDs
    MGI:2156378
    NCBI Gene: 386454
  • Alliance
    gene page
  • Transcription Start Sites
    3 TSS
Location &
Maps
more
  • Sequence Map
    Chr17:37253943-37258878 bp, + strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 17, 19.16 cM
  • Mapping Data
    1 experiment
Strain
Comparison
more
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_2156378
 protein coding gene Chr17:37253810-37258878 (+)
129S1/SvImJ MGP_129S1SvImJ_G0023687
 protein coding gene Chr17:37298906-37303968 (+)
A/J MGP_AJ_G0023645
 protein coding gene Chr17:36122206-36127258 (+)
AKR/J MGP_AKRJ_G0023616
 protein coding gene Chr17:36557057-36562109 (+)
BALB/cJ MGP_BALBcJ_G0023652
 protein coding gene Chr17:36364841-36369907 (+)
C3H/HeJ MGP_C3HHeJ_G0023414
 protein coding gene Chr17:37071104-37076156 (+)
C57BL/6NJ MGP_C57BL6NJ_G0024090
 protein coding gene Chr17:38893602-38898670 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0021558
 protein coding gene Chr17:33937625-33942682 (+)
CAST/EiJ MGP_CASTEiJ_G0022899
 protein coding gene Chr17:37202718-37207786 (+)
CBA/J MGP_CBAJ_G0023391
 protein coding gene Chr17:40411695-40416747 (+)
DBA/2J MGP_DBA2J_G0023516
 protein coding gene Chr17:35514842-35519908 (+)
FVB/NJ MGP_FVBNJ_G0023489
 protein coding gene Chr17:35123331-35128395 (+)
LP/J MGP_LPJ_G0023594
 protein coding gene Chr17:37828732-37833794 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0023512
 protein coding gene Chr17:39206322-39211386 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0024135
 protein coding gene Chr17:36896934-36902004 (+)
PWK/PhJ MGP_PWKPhJ_G0022651
 protein coding gene Chr17:34293374-34298435 (+)
SPRET/EiJ MGP_SPRETEiJ_G0022470
 protein coding gene Chr17:34981591-34986506 (+)
WSB/EiJ MGP_WSBEiJ_G0022966
 protein coding gene Chr17:37216212-37221276 (+)



Homology
more
  • Human Ortholog
    RNF39, ring finger protein 39
  • Vertebrate Orthologs
    2
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    RNF39, ring finger protein 39
  • Synonyms
    FAP216, HZF, HZFW, LIRF
  • Links
    NCBI Gene ID: 80352
    neXtProt AC: NX_Q9H2S5
    UniProt: Q9H2S5

  • Chr Location
    6p22.1; chr6:30070266-30075849 (-)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    3 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    3
  • GO References
    1
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    706
  • cDNA Data
    12
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic 386454 NCBI Gene Model | MGI Sequence Detail 4936 C57BL/6J ±  kb
transcript NM_001099632 RefSeq | MGI Sequence Detail 1446 Not Specified  
polypeptide NP_001093102 RefSeq | MGI Sequence Detail 352 Not Specified  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 12
    cDNA 12

    Microarray probesets 2
Other
Accession IDs
less
MGI:2685166, MGI:2686632, MGI:2686633, MGI:3040799
References
more
  • Summaries
    All 19
    Gene Ontology 1
    Phenotypes 3
  • Earliest
    J:73110 Matsuo R, et al., LIRF, a Gene Induced during Hippocampal Long-Term Potentiation as an Immediate-Early Gene, Encodes a Novel RING Finger Protein. Biochem Biophys Res Commun. 2001 Nov 30;289(2):479-84
  • Latest
    J:357976 Wang W, et al., RNF39 facilitates antiviral immune responses by promoting K63-linked ubiquitination of STING. Int Immunopharmacol. 2024 Dec 5;142(Pt A):113091
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
11/12/2024
MGI 6.24 		The Jackson Laboratory