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Apobr Gene Detail
Summary
  • Symbol
    Apobr
  • Name
    apolipoprotein B receptor
  • Synonyms
    Apob-48r, Apob48r
  • Feature Type
    protein coding gene
  • IDs
    MGI:2176230
    NCBI Gene: 171504
  • Alliance
    gene page
  • Transcription Start Sites
    9 TSS
Location &
Maps
more
  • Sequence Map
    Chr7:126184114-126188284 bp, + strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 7, 69.17 cM
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    166 from dbSNP Build 142
  • Strain Annotations
    18
  • PCR
    1
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_2176230
 protein coding gene Chr7:126184092-126188297 (+)
129S1/SvImJ MGP_129S1SvImJ_G0032987
 protein coding gene Chr7:130868214-130872384 (+)
A/J MGP_AJ_G0032970
 protein coding gene Chr7:127405549-127409783 (+)
AKR/J MGP_AKRJ_G0032902
 protein coding gene Chr7:130628403-130632573 (+)
BALB/cJ MGP_BALBcJ_G0032975
 protein coding gene Chr7:127063092-127067262 (+)
C3H/HeJ MGP_C3HHeJ_G0032685
 protein coding gene Chr7:130558120-130562290 (+)
C57BL/6NJ MGP_C57BL6NJ_G0033481
 protein coding gene Chr7:135958310-135962480 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0030453
 protein coding gene Chr7:128595212-128599465 (+)
CAST/EiJ MGP_CASTEiJ_G0032013
 protein coding gene Chr7:122351692-122355926 (+)
CBA/J MGP_CBAJ_G0032658
 protein coding gene Chr7:140529985-140534155 (+)
DBA/2J MGP_DBA2J_G0032810
 protein coding gene Chr7:125381575-125385745 (+)
FVB/NJ MGP_FVBNJ_G0032763
 protein coding gene Chr7:125231279-125235449 (+)
LP/J MGP_LPJ_G0032904
 protein coding gene Chr7:132333017-132337187 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0032795
 protein coding gene Chr7:141718084-141722254 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0033500
 protein coding gene Chr7:129644956-129649190 (+)
PWK/PhJ MGP_PWKPhJ_G0031721
 protein coding gene Chr7:118369648-118373818 (+)
SPRET/EiJ MGP_SPRETEiJ_G0031567
 protein coding gene Chr7:116473565-116477792 (+)
WSB/EiJ MGP_WSBEiJ_G0032126
 protein coding gene Chr7:130612453-130616623 (+)



Homology
more
  • Human Ortholog
    APOBR, apolipoprotein B receptor
  • Vertebrate Orthologs
    2
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    APOBR, apolipoprotein B receptor
  • Synonyms
    APOB100R, APOB48R
  • Links
    NCBI Gene ID: 55911
    neXtProt AC: NX_Q0VD83
    UniProt: Q0VD83

  • Chr Location
    16p12.1; chr16:28494643-28498964 (+)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    6 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    12
  • GO References
    5
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    706
  • cDNA Data
    36
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000042759 Ensembl Gene Model | MGI Sequence Detail 4171 C57BL/6J ±  kb
transcript ENSMUST00000039522 Ensembl | MGI Sequence Detail 3685 Not Applicable  
polypeptide ENSMUSP00000042028 Ensembl | MGI Sequence Detail 942 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 37
    cDNA 36
    Primer pair 1

    Microarray probesets 3
References
more
  • Summaries
    All 30
    Gene Ontology 5
    Phenotypes 6
  • Earliest
    J:78921 Brown ML, et al., The murine macrophage apoB-48 receptor gene (Apob-48r): homology to the human receptor. J Lipid Res. 2002 Aug;43(8):1181-91
  • Latest
    J:345621 Adams DJ, et al., Genetic determinants of micronucleus formation in vivo. Nature. 2024 Mar;627(8002):130-136
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
11/19/2024
MGI 6.24 		The Jackson Laboratory