About   Help   FAQ
Or12d17 Gene Detail
Summary
  • Symbol
    Or12d17
  • Name
    olfactory receptor family 12 subfamily D member 17
  • Synonyms
    GA_x6K02T2PSCP-1914078-1915022, MOR250-1, Olfr109
  • Feature Type
    protein coding gene
  • IDs
    MGI:2177492
    NCBI Gene: 258832
  • Alliance
    gene page
Location &
Maps
more
  • Sequence Map
    Chr17:37777099-37778043 bp, + strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 17, 19.16 cM
  • Mapping Data
    1 experiment
Strain
Comparison
more
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_2177492
 protein coding gene Chr17:37769807-37782481 (+)
129S1/SvImJ MGP_129S1SvImJ_G0023713
 protein coding gene Chr17:37875508-37876452 (+)
A/J MGP_AJ_G0023671
 protein coding gene Chr17:36714593-36715537 (+)
AKR/J MGP_AKRJ_G0023642
 protein coding gene Chr17:37131764-37132708 (+)
BALB/cJ MGP_BALBcJ_G0023677
 protein coding gene Chr17:36927151-36928095 (+)
C3H/HeJ MGP_C3HHeJ_G0023439
 protein coding gene Chr17:37673688-37674632 (+)
C57BL/6NJ MGP_C57BL6NJ_G0024115
 protein coding gene Chr17:39496652-39497596 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0021584
 protein coding gene Chr17:34448786-34449730 (+)
CAST/EiJ MGP_CASTEiJ_G0022925
 protein coding gene Chr17:37762311-37763255 (+)
CBA/J MGP_CBAJ_G0023416
 protein coding gene Chr17:41054772-41055716 (+)
DBA/2J MGP_DBA2J_G0023542
 protein coding gene Chr17:36051452-36052396 (+)
FVB/NJ MGP_FVBNJ_G0023515
 protein coding gene Chr17:35668335-35669279 (+)
LP/J MGP_LPJ_G0023620
 protein coding gene Chr17:38445706-38446650 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0023538
 protein coding gene Chr17:39851712-39852656 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0024161
 protein coding gene Chr17:37483644-37484588 (+)
PWK/PhJ MGP_PWKPhJ_G0022672
 protein coding gene Chr17:34834754-34835698 (+)
SPRET/EiJ MGP_SPRETEiJ_G0022493
 protein coding gene Chr17:35562459-35563403 (+)
WSB/EiJ MGP_WSBEiJ_G0022989
 protein coding gene Chr17:37824791-37825735 (+)



Homology
more
  • Human Ortholog
    OR12D3, olfactory receptor family 12 subfamily D member 3
  • Vertebrate Orthologs
    36
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    OR12D3, olfactory receptor family 12 subfamily D member 3
  • Synonyms
    hs6M1-27
  • Links
    NCBI Gene ID: 81797
    neXtProt AC: NX_Q9UGF7
    UniProt: Q9UGF7

  • Chr Location
    6p22.1; chr6:29373423-29375291 (-)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    17 phenotypes from 1 allele in 1 genetic background
    6 phenotypes from multigenic genotypes
    1 phenotype reference
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Homozygous null mice show decreased diet-induced obesity and hepatic steatosis and improved glucose homeostasis in response to a high-fat diet.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    8
  • GO References
    2
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    706
  • cDNA Data
    1
  • Comparison Matrix
    Gene Expression + Phenotype
    • Sequences &
    Gene Models
    less
    Representative SequencesLengthStrain/SpeciesFlank
    genomic 258832 NCBI Gene Model | MGI Sequence Detail 945 C57BL/6J ±  kb
    transcript NM_146835 RefSeq | MGI Sequence Detail 945 Not Specified  
    polypeptide NP_667046 RefSeq | MGI Sequence Detail 314 Not Specified  
    For the selected sequence
    Protein
    Information
    less
    • UniProt
      1 Sequence
    • InterPro Domains
      IPR017452 GPCR, rhodopsin-like, 7TM
      IPR000276 G protein-coupled receptor, rhodopsin-like
      IPR050516 Olfactory G-protein coupled receptor
      IPR000725 Olfactory receptor
    Molecular
    Reagents
    less
    • All nucleic 1
      cDNA 1

      Microarray probesets 1
    Other
    Accession IDs
    less
    MGI:7276356
    References
    more
    • Summaries
      All 14
      Gene Ontology 2
      Phenotypes 1
    • Earliest
      J:74521 Zhang X, et al., The olfactory receptor gene superfamily of the mouse. Nat Neurosci. 2002 Feb;5(2):124-33
    • Latest
      J:321591 Cheng J, et al., Autonomous sensing of the insulin peptide by an olfactory G protein-coupled receptor modulates glucose metabolism. Cell Metab. 2022 Feb 1;34(2):240-255.e10
    Contributing Projects:
    Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
    Citing These Resources
    Funding Information
    Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
    Send questions and comments to User Support.     		last database update
    12/10/2024
    MGI 6.24     		The Jackson Laboratory