About   Help   FAQ
Stab1 Gene Detail
Summary
  • Symbol
    Stab1
  • Name
    stabilin 1
  • Synonyms
    mKIAA0246, MS-1
  • Feature Type
    protein coding gene
  • IDs
    MGI:2178742
    NCBI Gene: 192187
  • Alliance
    gene page
  • Transcription Start Sites
    16 TSS
Location &
Maps
more
  • Sequence Map
    Chr14:30860970-30890598 bp, - strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 14, 19.09 cM
  • Mapping Data
    1 experiment
Strain
Comparison
more
  • SNPs within 2kb
    745 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_2178742
 protein coding gene Chr14:30860970-30890616 (-)
129S1/SvImJ MGP_129S1SvImJ_G0021120
 protein coding gene Chr14:24311398-24342463 (-)
A/J MGP_AJ_G0021068
 protein coding gene Chr14:23392812-23422429 (-)
AKR/J MGP_AKRJ_G0021045
 protein coding gene Chr14:24516785-24546370 (-)
BALB/cJ MGP_BALBcJ_G0021072
 protein coding gene Chr14:23514447-23544492 (-)
C3H/HeJ MGP_C3HHeJ_G0020855
 protein coding gene Chr14:24382336-24413186 (-)
C57BL/6NJ MGP_C57BL6NJ_G0021504
 protein coding gene Chr14:25281471-25311919 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0019067
 protein coding gene Chr14:23455926-23486176 (-)
CAST/EiJ MGP_CASTEiJ_G0020380
 protein coding gene Chr14:24149559-24179175 (-)
CBA/J MGP_CBAJ_G0020822
 protein coding gene Chr14:26253797-26285087 (-)
DBA/2J MGP_DBA2J_G0020944
 protein coding gene Chr14:23422495-23451960 (-)
FVB/NJ MGP_FVBNJ_G0020928
 protein coding gene Chr14:23384863-23414315 (-)
LP/J MGP_LPJ_G0021013
 protein coding gene Chr14:24638603-24669439 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0020954
 protein coding gene Chr14:25518618-25548125 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0021537
 protein coding gene Chr14:24277398-24307718 (-)
PWK/PhJ MGP_PWKPhJ_G0020128
 protein coding gene Chr14:22878066-22908230 (-)
SPRET/EiJ MGP_SPRETEiJ_G0019952
 protein coding gene Chr14:23873826-23903372 (-)
WSB/EiJ MGP_WSBEiJ_G0020435
 protein coding gene Chr14:24336107-24367001 (-)



Homology
more
  • Human Ortholog
    STAB1, stabilin 1
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    STAB1, stabilin 1
  • Synonyms
    CLEVER-1, FEEL-1, FEEL1, FELE-1, FEX1, HRFT, SCARH2, STAB-1
  • Links
    NCBI Gene ID: 23166
    neXtProt AC: NX_Q9NY15
    UniProt: Q9NY15

  • Chr Location
    3p21.1; chr3:52495338-52524495 (+)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    1 phenotype from 1 allele in 2 genetic backgrounds
    12 phenotypes from multigenic genotypes
    2 images
    21 phenotype references
Mice homozygous for a knock-out allele exhibit no physical or behavioral abnormalities.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    20
  • GO References
    6
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    808
  • Tissues
    63
  • cDNA Data
    74
  • Literature Summary
    10
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000042286 Ensembl Gene Model | MGI Sequence Detail 29629 C57BL/6J ±  kb
transcript ENSMUST00000036618 Ensembl | MGI Sequence Detail 7999 Not Applicable  
polypeptide ENSMUSP00000046199 Ensembl | MGI Sequence Detail 2571 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 77
    cDNA 75
    Primer pair 2

    Microarray probesets 4
References
more
  • Summaries
    All 59
    Developmental Gene Expression 10
    Gene Ontology 6
    Phenotypes 21
  • Earliest
    J:75013 Politz O, et al., Stabilin-1 and -2 constitute a novel family of fasciclin-like hyaluronan receptor homologues. Biochem J. 2002 Feb 15;362(Pt 1):155-64
  • Latest
    J:354240 Krzistetzko J, et al., Association of Differentially Altered Liver Fibrosis with Deposition of TGFBi in Stabilin-Deficient Mice. Int J Mol Sci. 2023 Jun 30;24(13)
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support. 		last database update
11/12/2024
MGI 6.24 		The Jackson Laboratory