Pnma1 MGI Mouse Gene Detail - MGI:2180564 - paraneoplastic antigen MA1

Symbol

Pnma1
Name

paraneoplastic antigen MA1
Synonyms

5730402C15Rik

Feature Type

protein coding gene
IDs

MGI:2180564
NCBI Gene: 70481
Alliance

gene page
Transcription Start Sites

2 TSS

Sequence Map

Chr12:84192905-84195263 bp, - strand
From NCBI annotation of GRCm39
View this region in JBrowse
Genome Browsers

Ensembl | UCSC | NCBI

Genetic Map

Chromosome 12, 39.07 cM, cytoband D3
Mapping Data

2 experiments

SNPs within 2kb

116 from dbSNP Build 142
Strain Annotations

18

For selected strains:

Strain	Gene Model ID	Feature Type	Coordinates
C57BL/6J	MGI_C57BL6J_2180564	protein coding gene	Chr12:84192905-84195263 (-)
129S1/SvImJ	MGP_129S1SvImJ_G0019929	protein coding gene	Chr12:84829703-84832061 (-)
A/J	MGP_AJ_G0019886	protein coding gene	Chr12:81623534-81625892 (-)
AKR/J	MGP_AKRJ_G0019862	protein coding gene	Chr12:83832961-83835319 (-)
BALB/cJ	MGP_BALBcJ_G0019866	protein coding gene	Chr12:81954970-81957328 (-)
C3H/HeJ	MGP_C3HHeJ_G0019672	protein coding gene	Chr12:84308272-84310630 (-)
C57BL/6NJ	MGP_C57BL6NJ_G0020317	protein coding gene	Chr12:87272064-87274422 (-)
CAROLI/EiJ	MGP_CAROLIEiJ_G0017935	protein coding gene	Chr12:78534285-78536637 (-)
CAST/EiJ	MGP_CASTEiJ_G0019221	protein coding gene	Chr12:79244031-79246390 (-)
CBA/J	MGP_CBAJ_G0019643	protein coding gene	Chr12:90639510-90641868 (-)
DBA/2J	MGP_DBA2J_G0019758	protein coding gene	Chr12:81155380-81157738 (-)
FVB/NJ	MGP_FVBNJ_G0019744	protein coding gene	Chr12:80111077-80113435 (-)
LP/J	MGP_LPJ_G0019830	protein coding gene	Chr12:84714695-84717053 (-)
NOD/ShiLtJ	MGP_NODShiLtJ_G0019783	protein coding gene	Chr12:93573860-93576218 (-)
NZO/HlLtJ	MGP_NZOHlLtJ_G0020351	protein coding gene	Chr12:83433634-83435992 (-)
PWK/PhJ	MGP_PWKPhJ_G0018985	protein coding gene	Chr12:75640387-75642745 (-)
SPRET/EiJ	MGP_SPRETEiJ_G0018780	protein coding gene	Chr12:77911128-77913487 (-)
WSB/EiJ	MGP_WSBEiJ_G0019273	protein coding gene	Chr12:84101643-84104001 (-)

Human Ortholog

PNMA1, PNMA family member 1

Vertebrate Orthologs

2

Vertebrate Orthology Source

Alliance of Genome Resources

Human Ortholog

PNMA1, PNMA family member 1
Synonyms

MA1
Links

HGNC:9158

NCBI Gene ID: 9240

neXtProt AC: NX_Q8ND90

UniProt: Q8ND90
Chr Location

14q24.3; chr14:73711783-73714384 (-) GRCh38

MGI Vertebrate Homology

Pnma1 stringent orthology
1 human;1 mouse;1 rat
HCOP

vertebrate homology predictions: PNMA1
Gene Tree

Pnma1

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Phenotype Summary

5 phenotype references

All Mutations and Alleles

3
Chemically induced (other)

1
Endonuclease-mediated

1
Targeted

1
Genomic Mutations

1 involving Pnma1
Find Mice (IMSR)

9 strains or lines available

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All GO Annotations

6
GO References

3

Molecular Function

No experimental evidence to support Molecular Function annotation, following literature review. See J:73796.

Biological Process

carbohydrate derivative metabolism	cell differentiation	cell population proliferation	cellular component organization	DNA-templated transcription	establishment of localization	homeostatic process	immune system process	lipid metabolic process	programmed cell death	protein metabolic process	response to stimulus	signaling	system development

Cellular Component

cell projection	cytoplasmic vesicle	cytoskeleton	cytosol	endoplasmic reticulum	endosome	extracellular region	Golgi apparatus	mitochondrion	membraneless organelle	nucleus	organelle envelope	organelle lumen	plasma membrane	protein-containing complex	synapse	vacuole

Click cells to view annotations.

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Expression Overview

GXD's primary emphasis is on endogenous gene expression during development. Click on grid cells to view annotations.

Blue cells = expressed in wild-type.
Gray triangles = other expression annotations only
(e.g. absence of expression or data from mutants).

early conceptus	embryo ectoderm	embryo endoderm	embryo mesoderm	embryo mesenchyme	extraembryonic component	alimentary system	auditory system	branchial arches	cardiovascular system	connective tissue	endocrine system	exocrine system	hemolymphoid system	integumental system	limbs	liver and biliary system	musculoskeletal system	nervous system	olfactory system	reproductive system	respiratory system	urinary system	visual system

Click cells to view annotations.

Assay Results

706
cDNA Data

10

Tissue x Stage Matrix

Other Mouse Links

Allen Institute

GEO

Expression Atlas

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All Sequences

31
RefSeq

2
UniProt

1
CCDS

CCDS26040.1

Ensembl

ENSMUSG00000054383 (Evidence)
NCBI Gene

70481

			Length	Strain/Species	Flank
genomic	70481	NCBI Gene Model \| MGI Sequence Detail	2359	C57BL/6J	± kb
transcript	NM_027438	RefSeq \| MGI Sequence Detail	2360	C57BL/6
polypeptide	Q8C1C8	UniProt \| EBI \| MGI Sequence Detail	353	Not Applicable

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UniProt

1 Sequence
Protein Ontology

PR:000012929 paraneoplastic antigen Ma1

(term hierarchy)
InterPro Domains

IPR026523 Paraneoplastic antigen Ma

IPR048270 Paraneoplastic antigen Ma-like, C-terminal domain

IPR048271 Paraneoplastic antigen Ma-like, N-terminal domain

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All nucleic 10

cDNA 10

Microarray probesets 2

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MGI:1917731

Summaries

All 27

Gene Ontology 3

Phenotypes 5
Earliest

J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
Latest

J:345621 Adams DJ, et al., Genetic determinants of micronucleus formation in vivo. Nature. 2024 Mar;627(8002):130-136

TSS for Pnma1:

(View these features in JBrowse)

Transcription Start Site	Location	Distance from Gene 5'-end
Tssr116980	Chr12:84195223-84195273 (-)	15 bp
Tssr116979	Chr12:84194987-84195001 (-)	269 bp

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources Funding Information Warranty Disclaimer, Privacy Notice, Licensing, & Copyright Send questions and comments to User Support.	last database update 12/10/2024 MGI 6.24