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Ugp2 Gene Detail
Summary
  • Symbol
    Ugp2
  • Name
    UDP-glucose pyrophosphorylase 2
  • Synonyms
    MGC:38262
  • Feature Type
    protein coding gene
  • IDs
    MGI:2183447
    NCBI Gene: 216558
  • Alliance
    gene page
  • Transcription Start Sites
    10 TSS
Location &
Maps
more
  • Sequence Map
    Chr11:21271138-21321201 bp, - strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 11, 13.89 cM
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    1203 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_2183447
 protein coding gene Chr11:21271126-21321267 (-)
129S1/SvImJ MGP_129S1SvImJ_G0018072
 protein coding gene Chr11:18919833-18972185 (-)
A/J MGP_AJ_G0018045
 protein coding gene Chr11:18248982-18298322 (-)
AKR/J MGP_AKRJ_G0018009
 protein coding gene Chr11:18894707-18948492 (-)
BALB/cJ MGP_BALBcJ_G0018013
 protein coding gene Chr11:18364657-18413750 (-)
C3H/HeJ MGP_C3HHeJ_G0017827
 protein coding gene Chr11:18782351-18832652 (-)
C57BL/6NJ MGP_C57BL6NJ_G0018465
 protein coding gene Chr11:19761371-19811321 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0016123
 protein coding gene Chr11:17199888-17253476 (-)
CAST/EiJ MGP_CASTEiJ_G0017388
 protein coding gene Chr11:18776206-18833038 (-)
CBA/J MGP_CBAJ_G0017801
 protein coding gene Chr11:20609619-20667606 (-)
DBA/2J MGP_DBA2J_G0017911
 protein coding gene Chr11:18194428-18243751 (-)
FVB/NJ MGP_FVBNJ_G0017903
 protein coding gene Chr11:17957995-18006117 (-)
LP/J MGP_LPJ_G0017982
 protein coding gene Chr11:19069978-19122643 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0017929
 protein coding gene Chr11:21020465-21072773 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0018506
 protein coding gene Chr11:18977223-19026722 (-)
PWK/PhJ MGP_PWKPhJ_G0017169
 protein coding gene Chr11:18208876-18260518 (-)
SPRET/EiJ MGP_SPRETEiJ_G0016966
 protein coding gene Chr11:18702046-18749255 (-)
WSB/EiJ MGP_WSBEiJ_G0017442
 protein coding gene Chr11:18628786-18680762 (-)



Homology
more
  • Human Ortholog
    UGP2, UDP-glucose pyrophosphorylase 2
  • Vertebrate Orthologs
    4
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    UGP2, UDP-glucose pyrophosphorylase 2
  • Synonyms
    DEE83, EIEE83, pHC379, SVUGP2, UDPG, UDPGP, UDPGP2, UGP1, UGPP1, UGPP2
  • Links
    NCBI Gene ID: 7360
    neXtProt AC: NX_Q16851
    UniProt: Q16851

  • Chr Location
    2p15; chr2:63840952-63891562 (+)  GRCh38
Human Diseases
more
  • Diseases
    1 with human UGP2 associations

Human Disease Mouse Models
      
IDs
Click on a disease name to see all genes associated with that disease.

Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    2 phenotypes from 1 allele in 1 genetic background
    10 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
  • All Mutations and Alleles
    5
  • Chemically induced (other)
    1
  • Endonuclease-mediated
    2
  • Gene trapped
    2
  • Genomic Mutations
    1 involving Ugp2
  • Incidental Mutations
    APF
  • Find Mice (IMSR)
    21 strains or lines available
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    32
  • GO References
    9
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    834
  • Tissues
    105
  • cDNA Data
    180
  • Literature Summary
    13
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000001891 Ensembl Gene Model | MGI Sequence Detail 50064 C57BL/6J ±  kb
transcript ENSMUST00000102875 Ensembl | MGI Sequence Detail 2683 Not Applicable  
polypeptide ENSMUSP00000099939 Ensembl | MGI Sequence Detail 508 Not Applicable  
For the selected sequence
Protein
Information
less
  • UniProt
    3 Sequences
  • Protein Ontology
    PR:000017047 UTP--glucose-1-phosphate uridylyltransferase
    (term hierarchy)
  • EC
    2.7.7.9
  • InterPro Domains
    IPR029044 Nucleotide-diphospho-sugar transferases
    IPR002618 UDPGP family
    IPR016267 UTP--glucose-1-phosphate uridylyltransferase
  • GlyGen
    Q91ZJ5 2 sites, 1 N-linked glycan (1 site), 1 O-linked glycan (1 site)
Molecular
Reagents
less
  • All nucleic 184
    cDNA 180
    Primer pair 3
    Other 1

    Microarray probesets 3
References
more
  • Summaries
    All 53
    Developmental Gene Expression 13
    Gene Ontology 9
    Phenotypes 10
  • Earliest
    J:137335 Roderick TH, Chromosomal inversions in studies of mammalian mutagenesis. Genetics. 1979 May;92(1 Pt 1 Suppl):s121-6
  • Latest
    J:345621 Adams DJ, et al., Genetic determinants of micronucleus formation in vivo. Nature. 2024 Mar;627(8002):130-136
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
12/10/2024
MGI 6.24 		The Jackson Laboratory