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Kcnj14 Gene Detail
Summary
  • Symbol
    Kcnj14
  • Name
    potassium inwardly-rectifying channel, subfamily J, member 14
  • Synonyms
    A930026G01Rik, IRK4, Kir2.4, MGC:25490, MGC:38951
  • Feature Type
    protein coding gene
  • IDs
    MGI:2384820
    NCBI Gene: 211480
  • Alliance
    gene page
  • Transcription Start Sites
    3 TSS
Location &
Maps
more
  • Sequence Map
    Chr7:45465871-45474180 bp, - strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 7, 29.53 cM
  • Mapping Data
    1 experiment
Strain
Comparison
more
  • SNPs within 2kb
    270 from dbSNP Build 142
  • Strain Annotations
    17
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_2384820
 protein coding gene Chr7:45465871-45474206 (-)
129S1/SvImJ MGP_129S1SvImJ_G0032249
 protein coding gene Chr7:46137659-46146640 (-)
A/J MGP_AJ_G0032228
 protein coding gene Chr7:45215359-45223498 (-)
AKR/J MGP_AKRJ_G0032164
 protein coding gene Chr7:46485535-46494651 (-)
BALB/cJ MGP_BALBcJ_G0032240
 protein coding gene Chr7:45213353-45223123 (-)
C3H/HeJ MGP_C3HHeJ_G0031955
 protein coding gene Chr7:46968220-46978330 (-)
C57BL/6NJ MGP_C57BL6NJ_G0032732
 protein coding gene Chr7:48397578-48411541 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0029746
 protein coding gene Chr7:47765789-47773911 (-)
CAST/EiJ MGP_CASTEiJ_G0031283
 protein coding gene Chr7:38413750-38422023 (-)
CBA/J MGP_CBAJ_G0031920
 protein coding gene Chr7:50020385-50028998 (-)
DBA/2J no annotation
FVB/NJ MGP_FVBNJ_G0032029
 protein coding gene Chr7:44669859-44679462 (-)
LP/J MGP_LPJ_G0032156
 protein coding gene Chr7:46843017-46853962 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0032066
 protein coding gene Chr7:48686578-48704636 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0016274
 protein coding gene Chr1:7946442-7954017 (+)
PWK/PhJ MGP_PWKPhJ_G0031006
 protein coding gene Chr7:38265319-38273560 (-)
SPRET/EiJ MGP_SPRETEiJ_G0030844
 protein coding gene Chr7:33721792-33729970 (-)
WSB/EiJ MGP_WSBEiJ_G0031401
 protein coding gene Chr7:46187135-46195886 (-)



Homology
more
  • Human Ortholog
    KCNJ14, potassium inwardly rectifying channel subfamily J member 14
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    KCNJ14, potassium inwardly rectifying channel subfamily J member 14
  • Synonyms
    IRK4, KIR2.4
  • Links
    NCBI Gene ID: 3770
    neXtProt AC: NX_Q9UNX9
    UniProt: Q9UNX9

  • Chr Location
    19q13.33; chr19:48455574-48466980 (+)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    7 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    12
  • GO References
    5
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    1085
  • Tissues
    49
  • cDNA Data
    27
  • Literature Summary
    6
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic 211480 NCBI Gene Model | MGI Sequence Detail 8310 C57BL/6J ±  kb
transcript NM_145963 RefSeq | MGI Sequence Detail 2659 C57BL/6  
polypeptide Q8JZN3 UniProt | EBI | MGI Sequence Detail 434 Not Applicable  
For the selected sequence
Protein
Information
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  • UniProt
    3 Sequences
  • Protein Ontology
    PR:000001982 ATP-sensitive inward rectifier potassium channel 14
    (term hierarchy)
  • InterPro Domains
    IPR014756 Immunoglobulin E-set
    IPR041647 Inward rectifier potassium channel, C-terminal
    IPR016449 Potassium channel, inwardly rectifying, Kir
    IPR013518 Potassium channel, inwardly rectifying, Kir, cytoplasmic
    IPR040445 Potassium channel, inwardly rectifying, transmembrane domain
Molecular
Reagents
less
  • All nucleic 29
    cDNA 28
    Primer pair 1

    Microarray probesets 3
Other
Accession IDs
less
MGI:2444193
References
more
  • Summaries
    All 36
    Developmental Gene Expression 6
    Gene Ontology 5
    Phenotypes 7
  • Earliest
    J:80000 The FANTOM Consortium and The RIKEN Genome Exploration Research Group Phase I & II Team, Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs. Nature. 2002;420:563-573
  • Latest
    J:345621 Adams DJ, et al., Genetic determinants of micronucleus formation in vivo. Nature. 2024 Mar;627(8002):130-136
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
11/12/2024
MGI 6.24 		The Jackson Laboratory