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Cep164 Gene Detail
Summary
  • Symbol
    Cep164
  • Name
    centrosomal protein 164
  • Synonyms
    MGC:38792
  • Feature Type
    protein coding gene
  • IDs
    MGI:2384878
    NCBI Gene: 214552
  • Alliance
    gene page
  • Transcription Start Sites
    7 TSS
Location &
Maps
more
  • Sequence Map
    Chr9:45678244-45739984 bp, - strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 9, 25.10 cM
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    1767 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_2384878
 protein coding gene Chr9:45678244-45739989 (-)
129S1/SvImJ MGP_129S1SvImJ_G0034740
 protein coding gene Chr9:44350330-44419716 (-)
A/J MGP_AJ_G0034721
 protein coding gene Chr9:43109028-43171938 (-)
AKR/J MGP_AKRJ_G0034648
 protein coding gene Chr9:43989110-44054402 (-)
BALB/cJ MGP_BALBcJ_G0034712
 protein coding gene Chr9:42832314-42895100 (-)
C3H/HeJ MGP_C3HHeJ_G0034423
 protein coding gene Chr9:44447950-44513327 (-)
C57BL/6NJ MGP_C57BL6NJ_G0035233
 protein coding gene Chr9:45636566-45703511 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0032147
 protein coding gene Chr9:42648652-42713041 (-)
CAST/EiJ MGP_CASTEiJ_G0033745
 protein coding gene Chr9:44310481-44373975 (-)
CBA/J MGP_CBAJ_G0034395
 protein coding gene Chr9:47307482-47371060 (-)
DBA/2J MGP_DBA2J_G0034554
 protein coding gene Chr9:42984879-43047660 (-)
FVB/NJ MGP_FVBNJ_G0034495
 protein coding gene Chr9:42250722-42313533 (-)
LP/J MGP_LPJ_G0034635
 protein coding gene Chr9:44674481-44746525 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0034539
 protein coding gene Chr9:49082524-49147982 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0035254
 protein coding gene Chr9:43904069-43966253 (-)
PWK/PhJ MGP_PWKPhJ_G0033450
 protein coding gene Chr9:42886676-42950804 (-)
SPRET/EiJ MGP_SPRETEiJ_G0033286
 protein coding gene Chr9:44223904-44288133 (-)
WSB/EiJ MGP_WSBEiJ_G0033858
 protein coding gene Chr9:43953762-44017498 (-)



Homology
more
  • Human Ortholog
    CEP164, centrosomal protein 164
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    CEP164, centrosomal protein 164
  • Synonyms
    NPHP15
  • Links
    NCBI Gene ID: 22897
    neXtProt AC: NX_Q9UPV0
    UniProt: Q9UPV0

  • Chr Location
    11q23.3; chr11:117314557-117413266 (+)  GRCh38
Human Diseases
more
  • Diseases
    2 with human CEP164 associations

Human Disease Mouse Models
      
IDs
IDs
Click on a disease name to see all genes associated with that disease.

Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    42 phenotypes from 3 alleles in 3 genetic backgrounds
    14 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Mice homozygous for a knock-out allele exhibit complete embryonic lethality during organogenesis, holoprosencephaly, cardiac looping defects, pericardial edema, and a severe decrease of primary cilia in the neural tube.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    23
  • GO References
    15
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    941
  • Tissues
    146
  • cDNA Data
    50
  • Literature Summary
    12
  • Comparison Matrix
    Gene Expression + Phenotype
    • Sequences &
    Gene Models
    less
    Representative SequencesLengthStrain/SpeciesFlank
    genomic 214552 NCBI Gene Model | MGI Sequence Detail 61741 C57BL/6J ±  kb
    transcript NM_001081373 RefSeq | MGI Sequence Detail 5513 C57BL/6  
    polypeptide Q5DU05 UniProt | EBI | MGI Sequence Detail 1446 Not Applicable  
    For the selected sequence
    Protein
    Information
    less
    Molecular
    Reagents
    less
    • All nucleic 50
      cDNA 50

      Microarray probesets 6
    Other
    Accession IDs
    less
    MGI:3529326
    References
    more
    • Summaries
      All 59
      Developmental Gene Expression 12
      Gene Ontology 15
      Phenotypes 14
    • Earliest
      J:82808 Strausberg RL, et al., Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Proc Natl Acad Sci U S A. 2002 Dec 24;99(26):16899-903
    • Latest
      J:345621 Adams DJ, et al., Genetic determinants of micronucleus formation in vivo. Nature. 2024 Mar;627(8002):130-136
    Contributing Projects:
    Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
    Citing These Resources
    Funding Information
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    Send questions and comments to User Support.     		last database update
    12/17/2024
    MGI 6.24     		The Jackson Laboratory