Ubtd1 Gene Detail

Summary

• Symbol
  Ubtd1
• Name
  ubiquitin domain containing 1
• Synonyms
  MGC:28905

• Feature Type
  protein coding gene
• IDs
  MGI:2385092
  NCBI Gene: 226122
• Alliance
  gene page
• Transcription Start Sites
  10 TSS

Location &
Maps

• Sequence Map
  Chr19:41970202-42023082 bp, + strand

  From Ensembl annotation of GRCm39
  

• View this region in JBrowse
  

• Genome Browsers
  Ensembl | UCSC | NCBI

• Genetic Map
  Chromosome 19, 35.56 cM
• Mapping Data
  2 experiments

Strain
Comparison

• SNPs within 2kb
  1380 from dbSNP Build 142
• Strain Annotations
  18

Strain	Gene Model ID	Feature Type	Coordinates
C57BL/6J	MGI_C57BL6J_2385092	protein coding gene	Chr19:41970202-42023089 (+)
129S1/SvImJ	MGP_129S1SvImJ_G0025134	protein coding gene	Chr19:41287515-41346426 (+)
A/J	MGP_AJ_G0025111	protein coding gene	Chr19:39303341-39359781 (+)
AKR/J	MGP_AKRJ_G0025079	protein coding gene	Chr19:40594359-40651135 (+)
BALB/cJ	MGP_BALBcJ_G0025105	protein coding gene	Chr19:39362208-39420181 (+)
C3H/HeJ	MGP_C3HHeJ_G0024865	protein coding gene	Chr19:40744395-40800030 (+)
C57BL/6NJ	MGP_C57BL6NJ_G0025548	protein coding gene	Chr19:42359734-42412214 (+)
CAROLI/EiJ	MGP_CAROLIEiJ_G0022962	protein coding gene	Chr19:38655920-38711374 (+)
CAST/EiJ	MGP_CASTEiJ_G0024330	protein coding gene	Chr19:40419997-40476688 (+)
CBA/J	MGP_CBAJ_G0024845	protein coding gene	Chr19:44432689-44496538 (+)
DBA/2J	MGP_DBA2J_G0024977	protein coding gene	Chr19:39153444-39209839 (+)
FVB/NJ	MGP_FVBNJ_G0024938	protein coding gene	Chr19:38927565-38984397 (+)
LP/J	MGP_LPJ_G0025063	protein coding gene	Chr19:41279351-41338040 (+)
NOD/ShiLtJ	MGP_NODShiLtJ_G0024969	protein coding gene	Chr19:44054684-44116114 (+)
NZO/HlLtJ	MGP_NZOHlLtJ_G0025606	protein coding gene	Chr19:40632707-40689910 (+)
PWK/PhJ	MGP_PWKPhJ_G0024079	protein coding gene	Chr19:39030617-39086223 (+)
SPRET/EiJ	MGP_SPRETEiJ_G0023883	protein coding gene	Chr19:39376154-39434381 (+)
WSB/EiJ	MGP_WSBEiJ_G0024400	protein coding gene	Chr19:40784882-40842461 (+)

Homology

• Human Ortholog
  UBTD1, ubiquitin domain containing 1

• Vertebrate Orthologs
  4

Vertebrate Orthology Source

Alliance of Genome Resources

• Human Ortholog
  UBTD1, ubiquitin domain containing 1
  
• Links
  HGNC:25683

  NCBI Gene ID: 80019

  neXtProt AC: NX_Q9HAC8

  UniProt: Q9HAC8

  
  
• Chr Location
  10q24.1-q24.2; chr10:97498924-97571206 (+)  GRCh38

---

• MGI Vertebrate Homology
  Ubtd1 stringent orthology
  1 human;1 mouse;1 rat;2 zebrafish
  
• HCOP
  vertebrate homology predictions: UBTD1
• Gene Tree
  Ubtd1
  

Mutations,
Alleles, and
Phenotypes

• Phenotype Summary
  7 phenotype references
  

• All Mutations and Alleles
  35
• Endonuclease-mediated
  1
• Gene trapped
  32
• Targeted
  2
• Incidental Mutations
  Mutagenetix , APF
• Find Mice (IMSR)
  20 strains or lines available

Gene Ontology
(GO)
Classifications

Expression

• Assay Results
  706
• cDNA Data
  32

Tissue x Stage Matrix

• Other Mouse Links
  Allen Institute
  GEO
  Expression Atlas
• Other Vertebrate Links
  Xenbase ubtd1
  ZFIN ubtd1b

Sequences &
Gene Models

• All Sequences
  36
• RefSeq
  6
• UniProt
  1
• CCDS
  CCDS29819.1

• Ensembl
  ENSMUSG00000025171 (Evidence)
• NCBI Gene
  226122

Representative Sequences			Length	Strain/Species
genomic	ENSMUSG00000025171	Ensembl Gene Model | MGI Sequence Detail	52881	C57BL/6J
transcript	ENSMUST00000026170	Ensembl | MGI Sequence Detail	1529	Not Applicable
polypeptide	ENSMUSP00000026170	Ensembl | MGI Sequence Detail	227	Not Applicable

Protein
Information

• UniProt
  1 Sequence
• Protein Ontology
  PR:000031330 ubiquitin domain-containing protein 1
  (term hierarchy)
• InterPro Domains
  IPR032752 DC-UbP/UBTD2, N-terminal domain
  IPR038169 DC-UbP/UBTD2, N-terminal domain superfamily
  IPR019956 Ubiquitin domain
  IPR039869 Ubiquitin domain-containing protein 1/2
  IPR000626 Ubiquitin-like domain
  IPR029071 Ubiquitin-like domain superfamily

Molecular
Reagents

• All nucleic 32

  cDNA 32

  
  

  Microarray probesets 4

References

• Summaries
  All 27

  Phenotypes 7
• Earliest
  J:82808 Strausberg RL, et al., Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Proc Natl Acad Sci U S A. 2002 Dec 24;99(26):16899-903
• Latest
  J:345621 Adams DJ, et al., Genetic determinants of micronucleus formation in vivo. Nature. 2024 Mar;627(8002):130-136

TSS for Ubtd1:

(View these features in JBrowse)

Transcription Start Site	Location	Distance from Gene 5'-end
Tssr156451	Chr19:41969666-41969685 (+)	-526 bp
Tssr156452	Chr19:41969694-41969722 (+)	-494 bp
Tssr156453	Chr19:41969762-41969788 (+)	-427 bp
Tssr156454	Chr19:41969909-41969920 (+)	-287 bp
Tssr156455	Chr19:41970062-41970077 (+)	-132 bp
Tssr156456	Chr19:41970100-41970145 (+)	-79 bp
Tssr156457	Chr19:41970148-41970217 (+)	-19 bp
Tssr5517	Chr19:41970226-41970237 (+)	30 bp
Tssr156458	Chr19:42007829-42007850 (+)	37,638 bp
Tssr156459	Chr19:42010638-42010656 (+)	40,445 bp