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Acsbg1 Gene Detail
Summary
  • Symbol
    Acsbg1
  • Name
    acyl-CoA synthetase bubblegum family member 1
  • Synonyms
    BG1, Bgm, E230019G03Rik, GR-LACS, Lpd, mKIAA0631
  • Feature Type
    protein coding gene
  • IDs
    MGI:2385656
    NCBI Gene: 94180
  • Alliance
    gene page
  • Transcription Start Sites
    8 TSS
Location &
Maps
more
  • Sequence Map
    Chr9:54512161-54569154 bp, - strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 9, 29.70 cM
  • Mapping Data
    3 experiments
Strain
Comparison
more
  • SNPs within 2kb
    1585 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_2385656
 protein coding gene Chr9:54512161-54569169 (-)
129S1/SvImJ MGP_129S1SvImJ_G0034827
 protein coding gene Chr9:53656601-53713956 (-)
A/J MGP_AJ_G0034808
 protein coding gene Chr9:51942398-52000002 (-)
AKR/J MGP_AKRJ_G0034736
 protein coding gene Chr9:53119498-53178181 (-)
BALB/cJ MGP_BALBcJ_G0034800
 protein coding gene Chr9:51717308-51774867 (-)
C3H/HeJ MGP_C3HHeJ_G0034510
 protein coding gene Chr9:53588044-53645613 (-)
C57BL/6NJ MGP_C57BL6NJ_G0035319
 protein coding gene Chr9:55162347-55222829 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0032231
 protein coding gene Chr9:51356517-51416557 (-)
CAST/EiJ MGP_CASTEiJ_G0033832
 protein coding gene Chr9:53597481-53656897 (-)
CBA/J MGP_CBAJ_G0034481
 protein coding gene Chr9:57054616-57135465 (-)
DBA/2J MGP_DBA2J_G0034640
 protein coding gene Chr9:51832964-51891621 (-)
FVB/NJ MGP_FVBNJ_G0034582
 protein coding gene Chr9:51035005-51092484 (-)
LP/J MGP_LPJ_G0034722
 protein coding gene Chr9:53966074-54026524 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0034625
 protein coding gene Chr9:58617972-58678171 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0035341
 protein coding gene Chr9:53123141-53186700 (-)
PWK/PhJ MGP_PWKPhJ_G0033536
 protein coding gene Chr9:51809411-51870289 (-)
SPRET/EiJ MGP_SPRETEiJ_G0033371
 protein coding gene Chr9:53393254-53452273 (-)
WSB/EiJ MGP_WSBEiJ_G0033944
 protein coding gene Chr9:53100429-53162781 (-)



Homology
more
  • Human Ortholog
    ACSBG1, acyl-CoA synthetase bubblegum family member 1
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    ACSBG1, acyl-CoA synthetase bubblegum family member 1
  • Synonyms
    BG, BG1, BGM, GR-LACS, LPD
  • Links
    NCBI Gene ID: 23205
    neXtProt AC: NX_Q96GR2
    UniProt: Q96GR2

  • Chr Location
    15q25.1; chr15:78167468-78245688 (-)  GRCh38
Human Diseases
less
  • Mutations/Alleles
    1 with disease annotations
  • References
    1 with disease annotations
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    6 phenotypes from 1 allele in 1 genetic background
    12 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Mice homozygous for a null mutation display abnormalities in gonadotropin induced changes in testosterone production, Leydig cell morphology and long chain and very long chain fatty acid levels.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    23
  • GO References
    8
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    1062
  • Tissues
    157
  • cDNA Data
    41
  • Literature Summary
    11
  • Comparison Matrix
    Gene Expression + Phenotype
    • Sequences &
    Gene Models
    less
    Representative SequencesLengthStrain/SpeciesFlank
    genomic ENSMUSG00000032281 Ensembl Gene Model | MGI Sequence Detail 56994 C57BL/6J ±  kb
    transcript ENSMUST00000034822 Ensembl | MGI Sequence Detail 2880 Not Applicable  
    polypeptide ENSMUSP00000034822 Ensembl | MGI Sequence Detail 721 Not Applicable  
    For the selected sequence
    Protein
    Information
    less
    Molecular
    Reagents
    less
    • All nucleic 44
      cDNA 41
      Primer pair 2
      Other 1

      Microarray probesets 3
    Other
    Accession IDs
    less
    MGI:2143449
    References
    more
    • Summaries
      All 51
      Developmental Gene Expression 11
      Diseases 1
      Gene Ontology 8
      Phenotypes 12
    • Earliest
      J:71861 Moriya-Sato A, et al., Novel acyl-CoA synthetase in adrenoleukodystrophy target tissues. Biochem Biophys Res Commun. 2000 Dec 9;279(1):62-8
    • Latest
      J:357932 Ye X, et al., Role of ACSBG1 in Brain Lipid Metabolism and X-Linked Adrenoleukodystrophy Pathogenesis: Insights from a Knockout Mouse Model. Cells. 2024 Oct 12;13(20)
    Contributing Projects:
    Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
    Citing These Resources
    Funding Information
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    Send questions and comments to User Support.     		last database update
    11/12/2024
    MGI 6.24     		The Jackson Laboratory