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Defb36 Gene Detail
Summary
  • Symbol
    Defb36
  • Name
    defensin beta 36
  • Synonyms
    Defb123
  • Feature Type
    protein coding gene
  • IDs
    MGI:2385956
    NCBI Gene: 266620
  • Alliance
    gene page
  • Transcription Start Sites
    5 TSS
Location &
Maps
more
  • Sequence Map
    Chr2:152446247-152454649 bp, + strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 2, 75.41 cM
  • Mapping Data
    1 experiment
Strain
Comparison
more
  • SNPs within 2kb
    413 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_2385956
 protein coding gene Chr2:152446247-152454649 (+)
129S1/SvImJ MGP_129S1SvImJ_G0026671
 protein coding gene Chr2:157167560-157175755 (+)
A/J MGP_AJ_G0026637
 protein coding gene Chr2:150894341-150902645 (+)
AKR/J MGP_AKRJ_G0026607
 protein coding gene Chr2:155300846-155309158 (+)
BALB/cJ MGP_BALBcJ_G0026646
 protein coding gene Chr2:151206452-151214835 (+)
C3H/HeJ MGP_C3HHeJ_G0026389
 protein coding gene Chr2:155681910-155693286 (+)
C57BL/6NJ MGP_C57BL6NJ_G0027095
 protein coding gene Chr2:161738421-161746643 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0024466
 protein coding gene Chr2:144487626-144496382 (+)
CAST/EiJ MGP_CASTEiJ_G0025850
 protein coding gene Chr2:155925860-155936679 (+)
CBA/J MGP_CBAJ_G0026367
 protein coding gene Chr2:167669993-167684712 (+)
DBA/2J MGP_DBA2J_G0026503
 protein coding gene Chr2:150108183-150116404 (+)
FVB/NJ MGP_FVBNJ_G0026469
 protein coding gene Chr2:148562725-148570926 (+)
LP/J MGP_LPJ_G0026607
 protein coding gene Chr2:157319697-157333430 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0026490
 protein coding gene Chr2:171778207-171787642 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0027151
 protein coding gene Chr2:155185985-155194218 (+)
PWK/PhJ MGP_PWKPhJ_G0025584
 protein coding gene Chr2:149629708-149638923 (+)
SPRET/EiJ MGP_SPRETEiJ_G0025387
 protein coding gene Chr2:154035677-154045571 (+)
WSB/EiJ MGP_WSBEiJ_G0025920
 protein coding gene Chr2:156101037-156110284 (+)



Homology
more
  • Human Ortholog
    DEFB123, defensin beta 123
  • Vertebrate Orthologs
    2
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    DEFB123, defensin beta 123
  • Synonyms
    DEFB-23, DEFB23, ESC42-RELD
  • Links
    NCBI Gene ID: 245936
    neXtProt AC: NX_Q8N688
    UniProt: Q8N688

  • Chr Location
    20q11.21; chr20:31440632-31450257 (+)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    4 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    3
  • GO References
    3
Molecular Function

No experimental evidence to support Molecular Function annotation, following literature review. See J:73796.
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    706
  • cDNA Data
    8
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic 266620 NCBI Gene Model | MGI Sequence Detail 8403 C57BL/6J ±  kb
transcript NM_001037247 RefSeq | MGI Sequence Detail 470 Not Specified  
polypeptide Q8K3U4 UniProt | EBI | MGI Sequence Detail 67 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 8
    cDNA 8

    Microarray probesets 2
References
more
  • Summaries
    All 26
    Gene Ontology 3
    Phenotypes 4
  • Earliest
    J:109968 Roderick TH, et al., Nineteen paracentric chromosomal inversions in mice. Genetics. 1974 Jan;76(1):109-17
  • Latest
    J:162220 Magdaleno S, et al., BGEM: an in situ hybridization database of gene expression in the embryonic and adult mouse nervous system. PLoS Biol. 2006 Apr;4(4):e86
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
12/10/2024
MGI 6.24 		The Jackson Laboratory