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Eif3l Gene Detail
Summary
  • Symbol
    Eif3l
  • Name
    eukaryotic translation initiation factor 3, subunit L
  • Synonyms
    0610011H21Rik, D15N1e, Eif3eip, Eif3s6ip, HSP-66Y, MGC:37328, PAF67
  • Feature Type
    protein coding gene
  • IDs
    MGI:2386251
    NCBI Gene: 223691
  • Alliance
    gene page
  • Transcription Start Sites
    5 TSS
Location &
Maps
more
  • Sequence Map
    Chr15:78959423-78978600 bp, + strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 15, 37.70 cM
  • Mapping Data
    3 experiments
Strain
Comparison
more
  • SNPs within 2kb
    759 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_2386251
 protein coding gene Chr15:78959379-78978605 (+)
129S1/SvImJ MGP_129S1SvImJ_G0022063
 protein coding gene Chr15:79331298-79351974 (+)
A/J MGP_AJ_G0022024
 protein coding gene Chr15:76591150-76610228 (+)
AKR/J MGP_AKRJ_G0021999
 protein coding gene Chr15:78716432-78736888 (+)
BALB/cJ MGP_BALBcJ_G0022030
 protein coding gene Chr15:76563069-76582529 (+)
C3H/HeJ MGP_C3HHeJ_G0021801
 protein coding gene Chr15:78715874-78735737 (+)
C57BL/6NJ MGP_C57BL6NJ_G0022473
 protein coding gene Chr15:82442073-82465857 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0020003
 protein coding gene Chr15:73072345-73091445 (+)
CAST/EiJ MGP_CASTEiJ_G0021322
 protein coding gene Chr15:79408424-79428709 (+)
CBA/J MGP_CBAJ_G0021766
 protein coding gene Chr15:84998194-85023266 (+)
DBA/2J MGP_DBA2J_G0021895
 protein coding gene Chr15:76069455-76088637 (+)
FVB/NJ MGP_FVBNJ_G0021873
 protein coding gene Chr15:75089548-75111787 (+)
LP/J MGP_LPJ_G0021963
 protein coding gene Chr15:79518388-79538839 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0021893
 protein coding gene Chr15:90150293-90171539 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0022487
 protein coding gene Chr15:78734348-78755312 (+)
PWK/PhJ MGP_PWKPhJ_G0021064
 protein coding gene Chr15:76074979-76094430 (+)
SPRET/EiJ MGP_SPRETEiJ_G0020901
 protein coding gene Chr15:78535724-78557706 (+)
WSB/EiJ MGP_WSBEiJ_G0021374
 protein coding gene Chr15:79114794-79138106 (+)



Homology
more
  • Human Ortholog
    EIF3L, eukaryotic translation initiation factor 3 subunit L
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    EIF3L, eukaryotic translation initiation factor 3 subunit L
  • Synonyms
    EIF3EIP, EIF3S11, EIF3S6IP, HSPC021, HSPC025, MSTP005
  • Links
    NCBI Gene ID: 51386
    neXtProt AC: NX_Q9Y262
    UniProt: Q9Y262

  • Chr Location
    22q13.1; chr22:37848868-37889407 (+)  GRCh38
Human Diseases
less
  • References
    1 with disease annotations
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    29 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    21
  • GO References
    7
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    710
  • Tissues
    1
  • cDNA Data
    323
  • Literature Summary
    1
Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic 223691 NCBI Gene Model | MGI Sequence Detail 19178 C57BL/6J ±  kb
transcript NM_145139 RefSeq | MGI Sequence Detail 1893 ZRU/MplStud  
polypeptide Q8QZY1 UniProt | EBI | MGI Sequence Detail 564 Not Applicable  
For the selected sequence
Protein
Information
less
  • UniProt
    2 Sequences
  • Protein Ontology
    PR:000006984 eukaryotic translation initiation factor 3 subunit L
    (term hierarchy)
  • InterPro Domains
    IPR000717 Proteasome component (PCI) domain
    IPR011990 Tetratricopeptide-like helical domain superfamily
    IPR019382 Translation initiation factor 3 complex subunit L
  • GlyGen
    Q8QZY1 1 site, 1 O-linked glycan (1 site)
Molecular
Reagents
less
  • All nucleic 324
    Genomic 1
    cDNA 323

    Microarray probesets 5
Other
Accession IDs
less
MGI:1276520, MGI:1915583
References
more
  • Summaries
    All 61
    Developmental Gene Expression 1
    Diseases 1
    Gene Ontology 7
    Phenotypes 29
  • Earliest
    J:7688 Lane PW, et al., Association of megacolon with a new dominant spotting gene (Dom) in the mouse. J Hered. 1984 Nov-Dec;75(6):435-9
  • Latest
    J:326541 Cyagen Biosciences Inc., Cyagen Biosciences Website. 2022;
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
12/10/2024
MGI 6.24 		The Jackson Laboratory