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Csrnp2 Gene Detail
Summary
  • Symbol
    Csrnp2
  • Name
    cysteine-serine-rich nuclear protein 2
  • Synonyms
    CSRNP-2, MGC:28165
  • Feature Type
    protein coding gene
  • IDs
    MGI:2386852
    NCBI Gene: 207785
  • Alliance
    gene page
  • Transcription Start Sites
    5 TSS
Location &
Maps
more
  • Sequence Map
    Chr15:100377451-100393120 bp, - strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 15, 56.32 cM
  • Mapping Data
    1 experiment
Strain
Comparison
more
  • SNPs within 2kb
    348 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_2386852
 protein coding gene Chr15:100377451-100393369 (-)
129S1/SvImJ MGP_129S1SvImJ_G0022353
 protein coding gene Chr15:102442638-102458324 (-)
A/J MGP_AJ_G0022315
 protein coding gene Chr15:98404666-98420321 (-)
AKR/J MGP_AKRJ_G0022291
 protein coding gene Chr15:101416515-101432175 (-)
BALB/cJ MGP_BALBcJ_G0022319
 protein coding gene Chr15:98525198-98540863 (-)
C3H/HeJ MGP_C3HHeJ_G0022089
 protein coding gene Chr15:101491529-101514179 (-)
C57BL/6NJ MGP_C57BL6NJ_G0022767
 protein coding gene Chr15:106296894-106315165 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0020292
 protein coding gene Chr15:94177414-94192922 (-)
CAST/EiJ MGP_CASTEiJ_G0021614
 protein coding gene Chr15:102357758-102374753 (-)
CBA/J MGP_CBAJ_G0022058
 protein coding gene Chr15:109934631-109950296 (-)
DBA/2J MGP_DBA2J_G0022185
 protein coding gene Chr15:97773264-97788855 (-)
FVB/NJ MGP_FVBNJ_G0022164
 protein coding gene Chr15:96785171-96800814 (-)
LP/J MGP_LPJ_G0022256
 protein coding gene Chr15:102614331-102630017 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0022185
 protein coding gene Chr15:113654830-113670611 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0022781
 protein coding gene Chr15:101423471-101439156 (-)
PWK/PhJ MGP_PWKPhJ_G0021353
 protein coding gene Chr15:97899575-97915309 (-)
SPRET/EiJ MGP_SPRETEiJ_G0021185
 protein coding gene Chr15:101320239-101335912 (-)
WSB/EiJ MGP_WSBEiJ_G0021664
 protein coding gene Chr15:102050393-102066079 (-)



Homology
more
  • Human Ortholog
    CSRNP2, cysteine and serine rich nuclear protein 2
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    CSRNP2, cysteine and serine rich nuclear protein 2
  • Synonyms
    C12orf2, C12orf22, FAM130A1, PPP1R72, TAIP-12
  • Links
    NCBI Gene ID: 81566
    neXtProt AC: NX_Q9H175
    UniProt: Q9H175

  • Chr Location
    12q13.12; chr12:51061205-51083664 (-)  GRCh38
Human Diseases
less
  • References
    1 with disease annotations
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    3 phenotypes from 1 allele in 1 genetic background
    5 phenotypes from multigenic genotypes
    27 phenotype references
  • All Mutations and Alleles
    14
  • Chemically induced (other)
    1
  • Endonuclease-mediated
    2
  • Gene trapped
    6
  • Radiation induced
    2
  • Targeted
    3
  • Genomic Mutations
    3 involving Csrnp2
  • Incidental Mutations
    APF
  • Find Mice (IMSR)
    19 strains or lines available
Mice homozygous for a knock-out allele are viable, fertile and healthy and display normal development, hematopoiesis and T cell function.
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
    13
  • GO References
    5
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    721
  • Tissues
    13
  • cDNA Data
    49
  • Literature Summary
    2
Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic 207785 NCBI Gene Model | MGI Sequence Detail 15670 C57BL/6J ±  kb
transcript NM_153407 RefSeq | MGI Sequence Detail 4126 C57BL/6  
polypeptide Q8BGQ2 UniProt | EBI | MGI Sequence Detail 534 Not Applicable  
For the selected sequence
Protein
Information
less
  • UniProt
    1 Sequence
  • Protein Ontology
    PR:000005956 cysteine/serine-rich nuclear protein 2
    (term hierarchy)
  • InterPro Domains
    IPR023260 Cysteine/serine-rich nuclear protein family
    IPR031972 Cysteine/serine-rich nuclear protein, N-terminal domain
Molecular
Reagents
less
  • All nucleic 50
    cDNA 50

    Microarray probesets 2
References
more
  • Summaries
    All 50
    Developmental Gene Expression 2
    Diseases 1
    Gene Ontology 5
    Phenotypes 27
  • Earliest
    J:7688 Lane PW, et al., Association of megacolon with a new dominant spotting gene (Dom) in the mouse. J Hered. 1984 Nov-Dec;75(6):435-9
  • Latest
    J:285676 Suzuki A, et al., Genes and microRNAs associated with mouse cleft palate: A systematic review and bioinformatics analysis. Mech Dev. 2018 Apr;150:21-27
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
12/10/2024
MGI 6.24 		The Jackson Laboratory