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Tut7 Gene Detail
Summary
  • Symbol
    Tut7
  • Name
    terminal uridylyl transferase 7
  • Synonyms
    6030448M23Rik, MGC:38585, Tent3b, Zcchc6
  • Feature Type
    protein coding gene
  • IDs
    MGI:2387179
    NCBI Gene: 214290
  • Alliance
    gene page
  • Transcription Start Sites
    9 TSS
Location &
Maps
more
  • Sequence Map
    Chr13:59919690-59971060 bp, - strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 13, 31.88 cM
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    1180 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_2387179
 protein coding gene Chr13:59919375-59971060 (-)
129S1/SvImJ MGP_129S1SvImJ_G0020645
 protein coding gene Chr13:59485642-59539542 (-)
A/J MGP_AJ_G0020600
 protein coding gene Chr13:57268242-57320092 (-)
AKR/J MGP_AKRJ_G0020576
 protein coding gene Chr13:58993612-59044862 (-)
BALB/cJ MGP_BALBcJ_G0020596
 protein coding gene Chr13:57530827-57582892 (-)
C3H/HeJ MGP_C3HHeJ_G0020393
 protein coding gene Chr13:58776138-58828064 (-)
C57BL/6NJ MGP_C57BL6NJ_G0021030
 protein coding gene Chr13:61288753-61339972 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0018612
 protein coding gene Chr13:55156746-55207291 (-)
CAST/EiJ MGP_CASTEiJ_G0019909
 protein coding gene Chr13:58971778-59031966 (-)
CBA/J MGP_CBAJ_G0020353
 protein coding gene Chr13:63603148-63658531 (-)
DBA/2J MGP_DBA2J_G0020477
 protein coding gene Chr13:56810378-56862527 (-)
FVB/NJ MGP_FVBNJ_G0020455
 protein coding gene Chr13:56295020-56346652 (-)
LP/J MGP_LPJ_G0020553
 protein coding gene Chr13:59750869-59803629 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0020485
 protein coding gene Chr13:62899433-62951409 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0021073
 protein coding gene Chr13:58587903-58640450 (-)
PWK/PhJ MGP_PWKPhJ_G0019664
 protein coding gene Chr13:56850576-56902616 (-)
SPRET/EiJ MGP_SPRETEiJ_G0019491
 protein coding gene Chr13:57466205-57518820 (-)
WSB/EiJ MGP_WSBEiJ_G0019971
 protein coding gene Chr13:59033501-59085340 (-)



Homology
more
  • Human Ortholog
    TUT7, terminal uridylyl transferase 7
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    TUT7, terminal uridylyl transferase 7
  • Synonyms
    PAPD6, TENT3B, ZCCHC6
  • Links
    NCBI Gene ID: 79670
    neXtProt AC: NX_Q5VYS8
    UniProt: Q5VYS8

  • Chr Location
    9q21.33; chr9:86287733-86354454 (-)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    4 phenotypes from multigenic genotypes
    13 phenotype references
Mice homozygous for conditional alleles of Tut4 and Tut7 activated in oocytes exhibit female infertility due to abnormal female meiosis I.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    28
  • GO References
    5
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
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Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    973
  • Tissues
    70
  • cDNA Data
    19
  • Literature Summary
    7
Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic 214290 NCBI Gene Model | MGI Sequence Detail 51371 C57BL/6J ±  kb
transcript NM_001373962 RefSeq | MGI Sequence Detail 5901 C57BL/6  
polypeptide Q5BLK4 UniProt | EBI | MGI Sequence Detail 1491 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 22
    cDNA 20
    Primer pair 2

    Microarray probesets 6
Other
Accession IDs
less
MGI:2145163, MGI:6155763
References
more
  • Summaries
    All 47
    Developmental Gene Expression 7
    Gene Ontology 5
    Phenotypes 13
  • Earliest
    J:182573 Roderick TH, Producing and detecting paracentric chromosomal inversions in mice. Mutat Res. 1971 Jan;11(1):59-69
  • Latest
    J:343914 Lin CC, et al., Terminal uridyltransferase 7 regulates TLR4-triggered inflammation by controlling Regnase-1 mRNA uridylation and degradation. Nat Commun. 2021 Jun 29;12(1):3878
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
12/10/2024
MGI 6.24 		The Jackson Laboratory