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Lrrc20 Gene Detail
Summary
  • Symbol
    Lrrc20
  • Name
    leucine rich repeat containing 20
  • Synonyms
    MGC:25719
  • Feature Type
    protein coding gene
  • IDs
    MGI:2387182
    NCBI Gene: 216011
  • Alliance
    gene page
  • Transcription Start Sites
    3 TSS
Location &
Maps
more
  • Sequence Map
    Chr10:61311580-61418570 bp, + strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 10, 32.22 cM
  • Mapping Data
    1 experiment
Strain
Comparison
more
  • SNPs within 2kb
    2894 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_2387182
 protein coding gene Chr10:61311579-61418570 (+)
129S1/SvImJ MGP_129S1SvImJ_G0017282
 protein coding gene Chr10:60824990-60940479 (+)
A/J MGP_AJ_G0017260
 protein coding gene Chr10:58999365-59109989 (+)
AKR/J MGP_AKRJ_G0017220
 protein coding gene Chr10:60541343-60654034 (+)
BALB/cJ MGP_BALBcJ_G0017220
 protein coding gene Chr10:59081305-59185867 (+)
C3H/HeJ MGP_C3HHeJ_G0017043
 protein coding gene Chr10:60448036-60556949 (+)
C57BL/6NJ MGP_C57BL6NJ_G0017678
 protein coding gene Chr10:63001136-63120977 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0015369
 protein coding gene Chr10:55972285-56077455 (+)
CAST/EiJ MGP_CASTEiJ_G0016614
 protein coding gene Chr10:60440127-60559751 (+)
CBA/J MGP_CBAJ_G0017015
 protein coding gene Chr10:65364523-65478722 (+)
DBA/2J MGP_DBA2J_G0017120
 protein coding gene Chr10:58274150-58381199 (+)
FVB/NJ MGP_FVBNJ_G0017114
 protein coding gene Chr10:57527603-57633505 (+)
LP/J MGP_LPJ_G0017195
 protein coding gene Chr10:61224413-61336179 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0017142
 protein coding gene Chr10:67659083-67776643 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0017716
 protein coding gene Chr10:60363178-60470789 (+)
PWK/PhJ MGP_PWKPhJ_G0016397
 protein coding gene Chr10:58110819-58219957 (+)
SPRET/EiJ MGP_SPRETEiJ_G0016180
 protein coding gene Chr10:59710976-59820201 (+)
WSB/EiJ MGP_WSBEiJ_G0016678
 protein coding gene Chr10:60269572-60384686 (+)



Homology
more
  • Human Ortholog
    LRRC20, leucine rich repeat containing 20
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    LRRC20, leucine rich repeat containing 20
  • Links
    NCBI Gene ID: 55222
    neXtProt AC: NX_Q8TCA0
    UniProt: Q8TCA0

  • Chr Location
    10q22.1; chr10:70298970-70382650 (-)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    17 phenotype references
  • All Mutations and Alleles
    11
  • Chemically induced (other)
    1
  • Endonuclease-mediated
    1
  • Gene trapped
    3
  • Radiation induced
    1
  • Targeted
    5
  • Genomic Mutations
    2 involving Lrrc20
  • Incidental Mutations
    APF
  • Find Mice (IMSR)
    17 strains or lines available
Gene Ontology
(GO)
Classifications
less
Molecular Function

No experimental evidence to support Molecular Function annotation, following literature review. See J:73796.
Biological Process

No experimental evidence to support Biological Process annotation, following literature review. See J:73796.
Cellular Component

No experimental evidence to support Cellular Component annotation, following literature review. See J:73796.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    713
  • Tissues
    3
  • cDNA Data
    9
  • Literature Summary
    1
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000037151 Ensembl Gene Model | MGI Sequence Detail 106991 C57BL/6J ±  kb
transcript ENSMUST00000049242 Ensembl | MGI Sequence Detail 3216 Not Applicable  
polypeptide ENSMUSP00000048042 Ensembl | MGI Sequence Detail 184 Not Applicable  
For the selected sequence
Protein
Information
less
  • UniProt
    1 Sequence
  • Protein Ontology
    PR:000031439 leucine-rich repeat-containing protein 20
    (term hierarchy)
  • InterPro Domains
    IPR051071 Leucine-rich repeat-containing bacterial E3 ubiquitin ligases
    IPR032675 Leucine-rich repeat domain superfamily
Molecular
Reagents
less
  • All nucleic 9
    cDNA 9

    Microarray probesets 3
References
more
  • Summaries
    All 35
    Developmental Gene Expression 1
    Phenotypes 17
  • Earliest
    J:109968 Roderick TH, et al., Nineteen paracentric chromosomal inversions in mice. Genetics. 1974 Jan;76(1):109-17
  • Latest
    J:345621 Adams DJ, et al., Genetic determinants of micronucleus formation in vivo. Nature. 2024 Mar;627(8002):130-136
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
12/10/2024
MGI 6.24 		The Jackson Laboratory