Obp2a MGI Mouse Gene Detail - MGI:2387617 - odorant binding protein 2A

Symbol

Obp2a
Name

odorant binding protein 2A
Synonyms

Lcn13, MGC:41397

Feature Type

protein coding gene
IDs

MGI:2387617
NCBI Gene: 227627
Alliance

gene page
Transcription Start Sites

7 TSS

Sequence Map

Chr2:25590055-25593338 bp, + strand
From Ensembl annotation of GRCm39
View this region in JBrowse
Genome Browsers

Ensembl | UCSC | NCBI

Genetic Map

Chromosome 2, 17.80 cM, cytoband A3
Mapping Data

2 experiments

SNPs within 2kb

231 from dbSNP Build 142
Strain Annotations

18

For selected strains:

Strain	Gene Model ID	Feature Type	Coordinates
C57BL/6J	MGI_C57BL6J_2387617	protein coding gene	Chr2:25587589-25593338 (+)
129S1/SvImJ	MGP_129S1SvImJ_G0025466	protein coding gene	Chr2:23619929-23623212 (+)
A/J	MGP_AJ_G0025443	protein coding gene	Chr2:22703987-22707252 (+)
AKR/J	MGP_AKRJ_G0025413	protein coding gene	Chr2:23452991-23456832 (+)
BALB/cJ	MGP_BALBcJ_G0025439	protein coding gene	Chr2:22810347-22813700 (+)
C3H/HeJ	MGP_C3HHeJ_G0025200	protein coding gene	Chr2:23388903-23394560 (+)
C57BL/6NJ	MGP_C57BL6NJ_G0025883	protein coding gene	Chr2:24373533-24376816 (+)
CAROLI/EiJ	MGP_CAROLIEiJ_G0023294	protein coding gene	Chr2:21601150-21604430 (+)
CAST/EiJ	MGP_CASTEiJ_G0024663	protein coding gene	Chr2:23263179-23266452 (+)
CBA/J	MGP_CBAJ_G0025178	protein coding gene	Chr2:25204659-25208488 (+)
DBA/2J	MGP_DBA2J_G0025311	protein coding gene	Chr2:22545496-22548749 (+)
FVB/NJ	MGP_FVBNJ_G0025273	protein coding gene	Chr2:22281476-22284747 (+)
LP/J	MGP_LPJ_G0025397	protein coding gene	Chr2:23551273-23554556 (+)
NOD/ShiLtJ	MGP_NODShiLtJ_G0025304	protein coding gene	Chr2:25380890-25385487 (+)
NZO/HlLtJ	MGP_NZOHlLtJ_G0025942	protein coding gene	Chr2:23417514-23420779 (+)
PWK/PhJ	MGP_PWKPhJ_G0024411	protein coding gene	Chr2:22344554-22347846 (+)
SPRET/EiJ	MGP_SPRETEiJ_G0024211	protein coding gene	Chr2:23546326-23549462 (+)
WSB/EiJ	MGP_WSBEiJ_G0024732	protein coding gene	Chr2:23477347-23480612 (+)

Human Ortholog

OBP2B, odorant binding protein 2B

Vertebrate Orthologs

2

Vertebrate Orthology Source

Alliance of Genome Resources

Human Ortholog

OBP2B, odorant binding protein 2B
Synonyms

LCN14, OBPIIb
Links

HGNC:23381

NCBI Gene ID: 29989

neXtProt AC: NX_Q9NPH6

UniProt: Q9NPH6
Chr Location

9q34.2; chr9:133205277-133223255 (-) GRCh38

MGI Vertebrate Homology

Obp2a stringent orthology
1 human;1 mouse;1 rat
HCOP

vertebrate homology predictions: OBP2B
Gene Tree

Obp2a

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Phenotype Summary

2 phenotypes from 1 allele in 1 genetic background
10 phenotype references

Phenotype Overview

Blue squares indicate phenotypes directly attributed to mutations/alleles of this gene.

adipose tissue	behavior/neurological	cardiovascular system	cellular	craniofacial	digestive/alimentary system	embryo	endocrine/exocrine glands	growth/size/body	hearing/vestibular/ear	hematopoietic system	homeostasis/metabolism	integument	immune system	limbs/digits/tail	liver/biliary system	mortality/aging	muscle	nervous system	pigmentation	renal/urinary system	reproductive system	respiratory system	skeleton	taste/olfaction	neoplasm	vision/eye

Click cells to view annotations.

All Mutations and Alleles

7
Endonuclease-mediated

3
Targeted

4
Find Mice (IMSR)

13 strains or lines available
Comparison Matrix

Gene Expression + Phenotype

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All GO Annotations

10
GO References

5

Molecular Function

carbohydrate derivative binding	cytoskeletal protein binding	DNA binding	enzyme regulator	hydrolase	ligase	lipid binding	oxidoreductase	RNA binding	signaling receptor activity	signaling receptor binding	transcription	transferase	transporter

Biological Process

carbohydrate derivative metabolism	cell differentiation	cell population proliferation	cellular component organization	DNA-templated transcription	establishment of localization	homeostatic process	immune system process	lipid metabolic process	programmed cell death	protein metabolic process	response to stimulus	signaling	system development

Cellular Component

cell projection	cytoplasmic vesicle	cytoskeleton	cytosol	endoplasmic reticulum	endosome	extracellular region	Golgi apparatus	mitochondrion	membraneless organelle	nucleus	organelle envelope	organelle lumen	plasma membrane	protein-containing complex	synapse	vacuole

Click cells to view annotations.

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Expression Overview

GXD's primary emphasis is on endogenous gene expression during development. Click on grid cells to view annotations.

Blue cells = expressed in wild-type.
Gray triangles = other expression annotations only
(e.g. absence of expression or data from mutants).

early conceptus	embryo ectoderm	embryo endoderm	embryo mesoderm	embryo mesenchyme	extraembryonic component	alimentary system	auditory system	branchial arches	cardiovascular system	connective tissue	endocrine system	exocrine system	hemolymphoid system	integumental system	limbs	liver and biliary system	musculoskeletal system	nervous system	olfactory system	reproductive system	respiratory system	urinary system	visual system

Click cells to view annotations.

Assay Results

709
Tissues

1
cDNA Data

3
Literature Summary

1

Tissue x Stage Matrix

Comparison Matrix

Gene Expression + Phenotype

Other Mouse Links

Allen Institute

GEO

Expression Atlas

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All Sequences

34
RefSeq

8
UniProt

1
CCDS

CCDS15788.1

Ensembl

ENSMUSG00000062061 (Evidence)
NCBI Gene

227627

			Length	Strain/Species	Flank
genomic	ENSMUSG00000062061	Ensembl Gene Model \| MGI Sequence Detail	3284	C57BL/6J	± kb
transcript	ENSMUST00000077667	Ensembl \| MGI Sequence Detail	744	Not Applicable
polypeptide	ENSMUSP00000076851	Ensembl \| MGI Sequence Detail	176	Not Applicable

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UniProt

1 Sequence
Protein Ontology

PR:000010021 epididymal-specific lipocalin-13

(term hierarchy)
InterPro Domains

IPR012674 Calycin

IPR002345 Lipocalin

IPR000566 Lipocalin/cytosolic fatty-acid binding domain

IPR002450 von Ebner's gland protein/ Bos/Can allergen
GlyGen

Q8K1H9 2 sites, 2 N-linked glycans (2 sites)

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All nucleic 4

cDNA 3

Primer pair 1

Microarray probesets 3

Summaries

All 34

Developmental Gene Expression 1

Gene Ontology 5

Phenotypes 10
Earliest

J:82808 Strausberg RL, et al., Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Proc Natl Acad Sci U S A. 2002 Dec 24;99(26):16899-903
Latest

J:345621 Adams DJ, et al., Genetic determinants of micronucleus formation in vivo. Nature. 2024 Mar;627(8002):130-136

TSS for Obp2a:

(View these features in JBrowse)

Transcription Start Site	Location	Distance from Gene 5'-end
Tssr16755	Chr2:25590051-25590054 (+)	-2 bp
Tssr16756	Chr2:25591300-25591305 (+)	1,248 bp
Tssr16757	Chr2:25591644-25591667 (+)	1,601 bp
Tssr16758	Chr2:25592041-25592048 (+)	1,990 bp
Tssr16759	Chr2:25592414-25592424 (+)	2,364 bp
Tssr16760	Chr2:25592493-25592518 (+)	2,451 bp
Tssr16761	Chr2:25592552-25592559 (+)	2,501 bp

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources Funding Information Warranty Disclaimer, Privacy Notice, Licensing, & Copyright Send questions and comments to User Support.	last database update 12/10/2024 MGI 6.24