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Cxcl17 Gene Detail
Summary
  • Symbol
    Cxcl17
  • Name
    C-X-C motif chemokine ligand 17
  • Synonyms
    MGC:37641
  • Feature Type
    protein coding gene
  • IDs
    MGI:2387642
    NCBI Gene: 232983
  • Alliance
    gene page
  • Transcription Start Sites
    10 TSS
Location &
Maps
more
  • Sequence Map
    Chr7:25099478-25112311 bp, - strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 7, 13.80 cM
  • Mapping Data
    1 experiment
Strain
Comparison
more
  • SNPs within 2kb
    373 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_2387642
 protein coding gene Chr7:25099478-25112311 (-)
129S1/SvImJ MGP_129S1SvImJ_G0031866
 protein coding gene Chr7:23870529-23885174 (-)
A/J MGP_AJ_G0031845
 protein coding gene Chr7:23248202-23261033 (-)
AKR/J MGP_AKRJ_G0031774
 protein coding gene Chr7:23795530-23810561 (-)
BALB/cJ MGP_BALBcJ_G0031852
 protein coding gene Chr7:23461993-23475285 (-)
C3H/HeJ MGP_C3HHeJ_G0031571
 protein coding gene Chr7:24230916-24244313 (-)
C57BL/6NJ MGP_C57BL6NJ_G0032314
 protein coding gene Chr7:24668871-24687331 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0029369
 protein coding gene Chr7:24669832-24680178 (-)
CAST/EiJ MGP_CASTEiJ_G0030911
 protein coding gene Chr7:17718804-17732721 (-)
CBA/J MGP_CBAJ_G0031536
 protein coding gene Chr7:25579950-25597607 (-)
DBA/2J MGP_DBA2J_G0031690
 protein coding gene Chr7:23150320-23162879 (-)
FVB/NJ MGP_FVBNJ_G0031643
 protein coding gene Chr7:23152783-23165571 (-)
LP/J MGP_LPJ_G0031769
 protein coding gene Chr7:24166814-24181442 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0031680
 protein coding gene Chr7:25280158-25295334 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0032346
 protein coding gene Chr7:23501352-23515701 (-)
PWK/PhJ MGP_PWKPhJ_G0030635
 protein coding gene Chr7:18097882-18110371 (-)
SPRET/EiJ MGP_SPRETEiJ_G0030466
 protein coding gene Chr7:14822601-14834371 (-)
WSB/EiJ MGP_WSBEiJ_G0031014
 protein coding gene Chr7:23687475-23701176 (-)



Homology
more
  • Human Ortholog
    CXCL17, C-X-C motif chemokine ligand 17
  • Vertebrate Orthologs
    2
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    CXCL17, C-X-C motif chemokine ligand 17
  • Synonyms
    Dcip1, DMC, UNQ473, VCC-1, VCC1
  • Links
    NCBI Gene ID: 284340
    neXtProt AC: NX_Q6UXB2
    UniProt: Q6UXB2

  • Chr Location
    19q13.2; chr19:42428278-42442946 (-)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    7 phenotypes from 1 allele in 1 genetic background
    19 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    21
  • GO References
    6
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    717
  • Tissues
    8
  • cDNA Data
    11
  • Literature Summary
    2
  • Comparison Matrix
    Gene Expression + Phenotype
    • Sequences &
    Gene Models
    less
    Representative SequencesLengthStrain/SpeciesFlank
    genomic 232983 NCBI Gene Model | MGI Sequence Detail 12834 C57BL/6J ±  kb
    transcript NM_153576 RefSeq | MGI Sequence Detail 760 Not Specified  
    polypeptide Q5UW37 UniProt | EBI | MGI Sequence Detail 119 Not Applicable  
    For the selected sequence
    Protein
    Information
    less
    Molecular
    Reagents
    less
    • All nucleic 12
      cDNA 11
      Primer pair 1

      Microarray probesets 4
    References
    more
    • Summaries
      All 44
      Developmental Gene Expression 2
      Gene Ontology 6
      Phenotypes 19
    • Earliest
      J:86696 Zambrowicz BP, et al., Wnk1 kinase deficiency lowers blood pressure in mice: a gene-trap screen to identify potential targets for therapeutic intervention. Proc Natl Acad Sci U S A. 2003 Nov 25;100(24):14109-14
    • Latest
      J:350380 Lowry E, et al., CXCL17 is a proinflammatory chemokine and promotes neutrophil trafficking. J Leukoc Biol. 2024 May 29;115(6):1177-1182
    Contributing Projects:
    Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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    Funding Information
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    Send questions and comments to User Support.     		last database update
    11/12/2024
    MGI 6.24     		The Jackson Laboratory