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Zmynd10 Gene Detail
Summary
  • Symbol
    Zmynd10
  • Name
    zinc finger, MYND domain containing 10
  • Synonyms
    Blu
  • Feature Type
    protein coding gene
  • IDs
    MGI:2387863
    NCBI Gene: 114602
  • Alliance
    gene page
  • Transcription Start Sites
    1 TSS
Location &
Maps
more
  • Sequence Map
    Chr9:107424497-107428518 bp, + strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 9, 58.12 cM
  • Mapping Data
    1 experiment
Strain
Comparison
more
  • SNPs within 2kb
    136 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_2387863
 protein coding gene Chr9:107424067-107428520 (+)
129S1/SvImJ MGP_129S1SvImJ_G0035256
 protein coding gene Chr9:109422791-109426791 (+)
A/J MGP_AJ_G0035235
 protein coding gene Chr9:105444286-105448286 (+)
AKR/J MGP_AKRJ_G0035167
 protein coding gene Chr9:108076416-108080416 (+)
BALB/cJ MGP_BALBcJ_G0035229
 protein coding gene Chr9:105113553-105117553 (+)
C3H/HeJ MGP_C3HHeJ_G0034939
 protein coding gene Chr9:108475576-108479576 (+)
C57BL/6NJ MGP_C57BL6NJ_G0035749
 protein coding gene Chr9:112414295-112418316 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0032647
 protein coding gene Chr9:102873228-102877179 (+)
CAST/EiJ MGP_CASTEiJ_G0034250
 protein coding gene Chr9:108408227-108412228 (+)
CBA/J MGP_CBAJ_G0034907
 protein coding gene Chr9:116387356-116391377 (+)
DBA/2J MGP_DBA2J_G0035068
 protein coding gene Chr9:104897971-104901992 (+)
FVB/NJ MGP_FVBNJ_G0035016
 protein coding gene Chr9:103662834-103666834 (+)
LP/J MGP_LPJ_G0035144
 protein coding gene Chr9:109628942-109632942 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0035055
 protein coding gene Chr9:118000432-118004432 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0035770
 protein coding gene Chr9:108347880-108351880 (+)
PWK/PhJ MGP_PWKPhJ_G0033957
 protein coding gene Chr9:105218117-105222139 (+)
SPRET/EiJ MGP_SPRETEiJ_G0033792
 protein coding gene Chr9:108403904-108407916 (+)
WSB/EiJ MGP_WSBEiJ_G0034371
 protein coding gene Chr9:108231016-108235016 (+)



Homology
more
  • Human Ortholog
    ZMYND10, zinc finger MYND-type containing 10
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    ZMYND10, zinc finger MYND-type containing 10
  • Synonyms
    BLU, CILD22, DNAAF7, FLU
  • Links
    NCBI Gene ID: 51364
    neXtProt AC: NX_O75800
    UniProt: O75800

  • Chr Location
    3p21.31; chr3:50341110-50345732 (-)  GRCh38
Human Diseases
more
  • Diseases
    1 with Zmynd10 mouse models; 1 with human ZMYND10 associations

Human Disease Mouse Models
      
IDs
 View 1 model
Click on a disease name to see all genes associated with that disease.

  • Mutations/Alleles
    1 with disease annotations
  • References
    1 with disease annotations
Mutations,
Alleles, and
Phenotypes
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  • Phenotype Summary
    21 phenotypes from 1 allele in 1 genetic background
    8 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Mice homozygous for a knock-out allele die prematurely exhibiting postnatal growth retardation, hydrocephalus, situs inversus, impaired mucociliary clearance, lung inflammation, and loss of ciliary motility and inner and outer dynein arm components without disruption of ciliogenesis.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    34
  • GO References
    7
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    728
  • Tissues
    10
  • cDNA Data
    25
  • Literature Summary
    3
  • Comparison Matrix
    Gene Expression + Phenotype
    • Sequences &
    Gene Models
    less
    Representative SequencesLengthStrain/SpeciesFlank
    genomic ENSMUSG00000010044 Ensembl Gene Model | MGI Sequence Detail 4022 C57BL/6J ±  kb
    transcript ENSMUST00000010188 Ensembl | MGI Sequence Detail 1765 Not Applicable  
    polypeptide ENSMUSP00000010188 Ensembl | MGI Sequence Detail 440 Not Applicable  
    For the selected sequence
    Protein
    Information
    less
    • UniProt
      2 Sequences
    • Protein Ontology
      PR:000032796 zinc finger MYND domain-containing protein 10
      (term hierarchy)
    • InterPro Domains
      IPR017333 Uncharacterised conserved protein UCP037948, zinc finger MYND-type
      IPR052298 Zinc finger MYND domain-containing protein 10
      IPR002893 Zinc finger, MYND-type
    Molecular
    Reagents
    less
    • All nucleic 28
      cDNA 25
      Primer pair 2
      Other 1

      Microarray probesets 3
    References
    more
    • Summaries
      All 35
      Developmental Gene Expression 3
      Diseases 1
      Gene Ontology 7
      Phenotypes 8
    • Earliest
      J:66052 Lerman MI, et al., The 630-kb lung cancer homozygous deletion region on human chromosome 3p21.3: identification and evaluation of the resident candidate tumor suppressor genes. The International Lung Cancer Chromosome 3p21.3 Tumor Suppressor Gene Consortium [In Process Citation]. Cancer Res. 2000 Nov 1;60(21):6116-33
    • Latest
      J:345621 Adams DJ, et al., Genetic determinants of micronucleus formation in vivo. Nature. 2024 Mar;627(8002):130-136
    Contributing Projects:
    Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
    Citing These Resources
    Funding Information
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    Send questions and comments to User Support.     		last database update
    11/12/2024
    MGI 6.24     		The Jackson Laboratory