Abca15 MGI Mouse Gene Detail - MGI:2388709 - ATP-binding cassette, sub-family A member 15

Symbol

Abca15
Name

ATP-binding cassette, sub-family A member 15
Synonyms

4930500I12Rik

Feature Type

protein coding gene
IDs

MGI:2388709
NCBI Gene: 320631
Alliance

gene page
Transcription Start Sites

2 TSS

Sequence Map

Chr7:119927893-120006910 bp, + strand
From Ensembl annotation of GRCm39
View this region in JBrowse
Genome Browsers

Ensembl | UCSC | NCBI

Genetic Map

Chromosome 7, 64.72 cM, cytoband F3
Mapping Data

2 experiments

SNPs within 2kb

2119 from dbSNP Build 142
Strain Annotations

18

For selected strains:

Strain	Gene Model ID	Feature Type	Coordinates
C57BL/6J	MGI_C57BL6J_2388709	protein coding gene	Chr7:119927709-120006925 (+)
129S1/SvImJ	MGP_129S1SvImJ_G0032928	protein coding gene	Chr7:124291767-124382026 (+)
A/J	MGP_AJ_G0032911	protein coding gene	Chr7:121069520-121151507 (+)
AKR/J	MGP_AKRJ_G0032843	protein coding gene	Chr7:124184618-124264998 (+)
BALB/cJ	MGP_BALBcJ_G0032916	protein coding gene	Chr7:120796958-120878821 (+)
C3H/HeJ	MGP_C3HHeJ_G0032626	protein coding gene	Chr7:124080193-124163228 (+)
C57BL/6NJ	MGP_C57BL6NJ_G0033422	protein coding gene	Chr7:129184555-129287792 (+)
CAROLI/EiJ	MGP_CAROLIEiJ_G0030394	protein coding gene	Chr7:122466693-122543812 (+)
CAST/EiJ	MGP_CASTEiJ_G0031954	protein coding gene	Chr7:115832523-115915069 (+)
CBA/J	MGP_CBAJ_G0032599	protein coding gene	Chr7:133531820-133622241 (+)
DBA/2J	MGP_DBA2J_G0032751	protein coding gene	Chr7:119110527-119197030 (+)
FVB/NJ	MGP_FVBNJ_G0032704	protein coding gene	Chr7:118946928-119028343 (+)
LP/J	MGP_LPJ_G0032845	protein coding gene	Chr7:125728904-125818854 (+)
NOD/ShiLtJ	MGP_NODShiLtJ_G0032736	protein coding gene	Chr7:134979165-135063345 (+)
NZO/HlLtJ	MGP_NZOHlLtJ_G0033442	protein coding gene	Chr7:123165882-123245602 (+)
PWK/PhJ	MGP_PWKPhJ_G0031662	protein coding gene	Chr7:112023775-112112373 (+)
SPRET/EiJ	MGP_SPRETEiJ_G0031508	protein coding gene	Chr7:109917253-110000952 (+)
WSB/EiJ	MGP_WSBEiJ_G0032067	protein coding gene	Chr7:124073517-124157696 (+)

Human Ortholog

ABCA15P, ATP binding cassette subfamily A member 15, pseudogene

Vertebrate Orthologs

2

Vertebrate Orthology Source

Alliance of Genome Resources

Human Ortholog

ABCA15P, ATP binding cassette subfamily A member 15, pseudogene
Synonyms

CRYM-AS1, NCRNA00169
Links

HGNC:34405

NCBI Gene ID: 400508
Chr Location

16p12.2; chr16:21300849-21339037 (+) GRCh38

MGI Vertebrate Homology

Abca15 stringent orthology
1 human;1 mouse;1 rat
HCOP

vertebrate homology predictions: ABCA15P
Gene Tree

Abca15

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Phenotype Summary

4 phenotype references

All Mutations and Alleles

5
Endonuclease-mediated

2
Targeted

3
Incidental Mutations

Mutagenetix , APF , CvDC
Find Mice (IMSR)

91 strains or lines available

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All GO Annotations

5
GO References

2

Molecular Function

carbohydrate derivative binding	cytoskeletal protein binding	DNA binding	enzyme regulator	hydrolase	ligase	lipid binding	oxidoreductase	RNA binding	signaling receptor activity	signaling receptor binding	transcription	transferase	transporter

Biological Process

carbohydrate derivative metabolism	cell differentiation	cell population proliferation	cellular component organization	DNA-templated transcription	establishment of localization	homeostatic process	immune system process	lipid metabolic process	programmed cell death	protein metabolic process	response to stimulus	signaling	system development

Cellular Component

cell projection	cytoplasmic vesicle	cytoskeleton	cytosol	endoplasmic reticulum	endosome	extracellular region	Golgi apparatus	mitochondrion	membraneless organelle	nucleus	organelle envelope	organelle lumen	plasma membrane	protein-containing complex	synapse	vacuole

Click cells to view annotations.

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Expression Overview

GXD's primary emphasis is on endogenous gene expression during development. Click on grid cells to view annotations.

Blue cells = expressed in wild-type.
Gray triangles = other expression annotations only
(e.g. absence of expression or data from mutants).

early conceptus	embryo ectoderm	embryo endoderm	embryo mesoderm	embryo mesenchyme	extraembryonic component	alimentary system	auditory system	branchial arches	cardiovascular system	connective tissue	endocrine system	exocrine system	hemolymphoid system	integumental system	limbs	liver and biliary system	musculoskeletal system	nervous system	olfactory system	reproductive system	respiratory system	urinary system	visual system

Click cells to view annotations.

Assay Results

726
Tissues

12
cDNA Data

6
Literature Summary

1

Tissue x Stage Matrix

Other Mouse Links

Allen Institute

GEO

Expression Atlas

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All Sequences

42
RefSeq

4
UniProt

4
CCDS

CCDS40109.1

Ensembl

ENSMUSG00000054746 (Evidence)
NCBI Gene

320631

			Length	Strain/Species	Flank
genomic	ENSMUSG00000054746	Ensembl Gene Model \| MGI Sequence Detail	79018	C57BL/6J	± kb
transcript	ENSMUST00000076272	Ensembl \| MGI Sequence Detail	5335	Not Applicable
polypeptide	ENSMUSP00000075621	Ensembl \| MGI Sequence Detail	1668	Not Applicable

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UniProt

4 Sequences
InterPro Domains

IPR003593 AAA+ ATPase domain

IPR013525 ABC-2 type transporter, transmembrane domain

IPR026082 ABC transporter A

IPR003439 ABC transporter-like, ATP-binding domain

IPR017871 ABC transporter-like, conserved site

IPR027417 P-loop containing nucleoside triphosphate hydrolase

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All nucleic 7

cDNA 6

Primer pair 1

Microarray probesets 2

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MGI:2444399

Summaries

All 19

Developmental Gene Expression 1

Gene Ontology 2

Phenotypes 4
Earliest

J:80000 The FANTOM Consortium and The RIKEN Genome Exploration Research Group Phase I & II Team, Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs. Nature. 2002;420:563-573
Latest

J:202604 Nagamachi A, et al., Haploinsufficiency of SAMD9L, an endosome fusion facilitator, causes myeloid malignancies in mice mimicking human diseases with monosomy 7. Cancer Cell. 2013 Sep 9;24(3):305-17

TSS for Abca15:

(View these features in JBrowse)

Transcription Start Site	Location	Distance from Gene 5'-end
Tssr68781	Chr7:119927883-119927914 (+)	6 bp
Tssr68782	Chr7:119927916-119927923 (+)	27 bp

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources Funding Information Warranty Disclaimer, Privacy Notice, Licensing, & Copyright Send questions and comments to User Support.	last database update 12/10/2024 MGI 6.24