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Sgcz Gene Detail
Summary
  • Symbol
    Sgcz
  • Name
    sarcoglycan zeta
  • Synonyms
    C230085N17Rik
  • Feature Type
    protein coding gene
  • IDs
    MGI:2388820
    NCBI Gene: 244431
  • Alliance
    gene page
  • Transcription Start Sites
    7 TSS
Location &
Maps
more
  • Sequence Map
    Chr8:37989452-39128662 bp, - strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 8, 23.31 cM
  • Mapping Data
    4 experiments
Strain
Comparison
more
  • SNPs within 2kb
    36941 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_2388820
 protein coding gene Chr8:37984994-39128857 (-)
129S1/SvImJ MGP_129S1SvImJ_G0033547
 protein coding gene Chr8:36235559-37462034 (-)
A/J MGP_AJ_G0033527
 protein coding gene Chr8:34867732-36031153 (-)
AKR/J MGP_AKRJ_G0033451
 protein coding gene Chr8:35946270-37112866 (-)
BALB/cJ MGP_BALBcJ_G0033523
 protein coding gene Chr8:34967862-36124582 (-)
C3H/HeJ MGP_C3HHeJ_G0033235
 protein coding gene Chr8:36320919-37506301 (-)
C57BL/6NJ MGP_C57BL6NJ_G0034039
 protein coding gene Chr8:37590655-38854476 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0030988
 protein coding gene Chr8:31732938-32769307 (-)
CAST/EiJ MGP_CASTEiJ_G0032563
 protein coding gene Chr8:35743965-36982628 (-)
CBA/J MGP_CBAJ_G0033213
 protein coding gene Chr8:39112400-40433985 (-)
DBA/2J MGP_DBA2J_G0033366
 protein coding gene Chr8:34776795-35910818 (-)
FVB/NJ MGP_FVBNJ_G0033311
 protein coding gene Chr8:34400328-35499401 (-)
LP/J MGP_LPJ_G0033456
 protein coding gene Chr8:36250524-37485300 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0033353
 protein coding gene Chr8:38471171-40143975 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0034058
 protein coding gene Chr8:36050912-37256825 (-)
PWK/PhJ MGP_PWKPhJ_G0032272
 protein coding gene Chr8:34309783-35443474 (-)
SPRET/EiJ MGP_SPRETEiJ_G0032104
 protein coding gene Chr8:35319677-36473311 (-)
WSB/EiJ MGP_WSBEiJ_G0032678
 protein coding gene Chr8:36268159-37454062 (-)



Homology
more
  • Human Ortholog
    SGCZ, sarcoglycan zeta
  • Vertebrate Orthologs
    2
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    SGCZ, sarcoglycan zeta
  • Synonyms
    ZSG1
  • Links
    NCBI Gene ID: 137868
    neXtProt AC: NX_Q96LD1
    UniProt: Q96LD1

  • Chr Location
    8p22; chr8:14084845-15238431 (-)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    4 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    12
  • GO References
    4
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    706
  • cDNA Data
    9
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000039539 Ensembl Gene Model | MGI Sequence Detail 1139211 C57BL/6J ±  kb
transcript ENSMUST00000118896 Ensembl | MGI Sequence Detail 2389 Not Applicable  
polypeptide ENSMUSP00000113912 Ensembl | MGI Sequence Detail 311 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 9
    cDNA 9

    Microarray probesets 1
Other
Accession IDs
less
MGI:2444342
References
more
  • Summaries
    All 26
    Gene Ontology 4
    Phenotypes 4
  • Earliest
    J:79436 Wheeler MT, et al., zeta-Sarcoglycan, a novel component of the sarcoglycan complex, is reduced in muscular dystrophy. Hum Mol Genet. 2002 Sep 1;11(18):2147-54
  • Latest
    J:240008 Levy R, et al., Collaborative cross mice in a genetic association study reveal new candidate genes for bone microarchitecture. BMC Genomics. 2015 Nov 26;16:1013
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
12/10/2024
MGI 6.24 		The Jackson Laboratory