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Fmo4 Gene Detail
Summary
  • Symbol
    Fmo4
  • Name
    flavin containing monooxygenase 4
  • Feature Type
    protein coding gene
  • IDs
    MGI:2429497
    NCBI Gene: 226564
  • Alliance
    gene page
  • Transcription Start Sites
    3 TSS
Location &
Maps
more
  • Sequence Map
    Chr1:162620757-162641541 bp, - strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 1, 70.34 cM
  • Mapping Data
    1 experiment
Strain
Comparison
more
  • SNPs within 2kb
    686 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_2429497
 protein coding gene Chr1:162620757-162643788 (-)
129S1/SvImJ MGP_129S1SvImJ_G0016664
 protein coding gene Chr1:168155593-168175450 (-)
A/J MGP_AJ_G0016645
 protein coding gene Chr1:161308350-161328525 (-)
AKR/J MGP_AKRJ_G0016611
 protein coding gene Chr1:166189727-166208378 (-)
BALB/cJ MGP_BALBcJ_G0016606
 protein coding gene Chr1:161826931-161845476 (-)
C3H/HeJ MGP_C3HHeJ_G0016430
 protein coding gene Chr1:166393236-166414838 (-)
C57BL/6NJ MGP_C57BL6NJ_G0017067
 protein coding gene Chr1:173804004-173822618 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0014776
 protein coding gene Chr1:153346223-153365463 (-)
CAST/EiJ MGP_CASTEiJ_G0016010
 protein coding gene Chr1:166046704-166066252 (-)
CBA/J MGP_CBAJ_G0016405
 protein coding gene Chr1:179998934-180019871 (-)
DBA/2J MGP_DBA2J_G0016511
 protein coding gene Chr1:160241658-160261073 (-)
FVB/NJ MGP_FVBNJ_G0016509
 protein coding gene Chr1:158670312-158688814 (-)
LP/J MGP_LPJ_G0016582
 protein coding gene Chr1:169260484-169284271 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0016534
 protein coding gene Chr1:187503939-187526890 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0017103
 protein coding gene Chr1:166019823-166040313 (-)
PWK/PhJ MGP_PWKPhJ_G0015796
 protein coding gene Chr1:159424248-159444000 (-)
SPRET/EiJ MGP_SPRETEiJ_G0015583
 protein coding gene Chr1:164877418-164884566 (+)
WSB/EiJ MGP_WSBEiJ_G0016072
 protein coding gene Chr1:166200080-166225175 (-)



Homology
more
  • Human Ortholog
    FMO4, flavin containing dimethylaniline monoxygenase 4
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    FMO4, flavin containing dimethylaniline monoxygenase 4
  • Synonyms
    FMO2
  • Links
    NCBI Gene ID: 2329
    neXtProt AC: NX_P31512
    UniProt: P31512

  • Chr Location
    1q24.3; chr1:171314183-171342084 (+)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    12 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    10
  • GO References
    7
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    800
  • Tissues
    94
  • cDNA Data
    4
  • Literature Summary
    1
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000026692 Ensembl Gene Model | MGI Sequence Detail 20785 C57BL/6J ±  kb
transcript ENSMUST00000028014 Ensembl | MGI Sequence Detail 1787 Not Applicable  
polypeptide ENSMUSP00000028014 Ensembl | MGI Sequence Detail 560 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 6
    Genomic 2
    cDNA 4

    Microarray probesets 3
References
more
  • Summaries
    All 34
    Developmental Gene Expression 1
    Gene Ontology 7
    Phenotypes 12
  • Earliest
    J:86696 Zambrowicz BP, et al., Wnk1 kinase deficiency lowers blood pressure in mice: a gene-trap screen to identify potential targets for therapeutic intervention. Proc Natl Acad Sci U S A. 2003 Nov 25;100(24):14109-14
  • Latest
    J:328499 Veeravalli S, et al., Flavin-Containing Monooxygenase 1 Catalyzes the Production of Taurine from Hypotaurine. Drug Metab Dispos. 2020 May;48(5):378-385
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
12/17/2024
MGI 6.24 		The Jackson Laboratory