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Abcc12 Gene Detail
Summary
  • Symbol
    Abcc12
  • Name
    ATP-binding cassette, sub-family C member 12
  • Synonyms
    4930467B22Rik, MRP9
  • Feature Type
    protein coding gene
  • IDs
    MGI:2441679
    NCBI Gene: 244562
  • Alliance
    gene page
  • Transcription Start Sites
    3 TSS
Location &
Maps
more
  • Sequence Map
    Chr8:87231197-87307317 bp, - strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 8, 42.06 cM, cytoband D3
  • Mapping Data
    4 experiments
Strain
Comparison
more
  • SNPs within 2kb
    2292 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_2441679
 protein coding gene Chr8:87208889-87307317 (-)
129S1/SvImJ MGP_129S1SvImJ_G0033907
 protein coding gene Chr8:87450061-87548667 (-)
A/J MGP_AJ_G0033890
 protein coding gene Chr8:84020097-84117342 (-)
AKR/J MGP_AKRJ_G0033816
 protein coding gene Chr8:86505359-86606612 (-)
BALB/cJ MGP_BALBcJ_G0033883
 protein coding gene Chr8:84167275-84263595 (-)
C3H/HeJ MGP_C3HHeJ_G0033594
 protein coding gene Chr8:87114642-87213227 (-)
C57BL/6NJ MGP_C57BL6NJ_G0034404
 protein coding gene Chr8:90812714-90913643 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0031344
 protein coding gene Chr8:78059135-78149293 (-)
CAST/EiJ MGP_CASTEiJ_G0032924
 protein coding gene Chr8:86520954-86621582 (-)
CBA/J MGP_CBAJ_G0033569
 protein coding gene Chr8:93886623-93989691 (-)
DBA/2J MGP_DBA2J_G0033722
 protein coding gene Chr8:83631906-83728041 (-)
FVB/NJ MGP_FVBNJ_G0033670
 protein coding gene Chr8:82582167-82675223 (-)
LP/J MGP_LPJ_G0033814
 protein coding gene Chr8:87571726-87675710 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0033713
 protein coding gene Chr8:96421303-96522950 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0034421
 protein coding gene Chr8:86492483-86587714 (-)
PWK/PhJ MGP_PWKPhJ_G0032628
 protein coding gene Chr8:82873863-82969531 (-)
SPRET/EiJ MGP_SPRETEiJ_G0032463
 protein coding gene Chr8:85255162-85349162 (-)
WSB/EiJ MGP_WSBEiJ_G0033036
 protein coding gene Chr8:86924518-87022426 (-)



Homology
more
  • Human Ortholog
    ABCC12, ATP binding cassette subfamily C member 12
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    ABCC12, ATP binding cassette subfamily C member 12
  • Synonyms
    MRP9
  • Links
    NCBI Gene ID: 94160
    neXtProt AC: NX_Q96J65
    UniProt: Q96J65

  • Chr Location
    16q12.1; chr16:48080882-48156018 (-)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    35 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    12
  • GO References
    8
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    855
  • Tissues
    119
  • cDNA Data
    18
  • Literature Summary
    2
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic 244562 NCBI Gene Model | MGI Sequence Detail 76121 C57BL/6J ±  kb
transcript NM_172912 RefSeq | MGI Sequence Detail 4511 ZRU/MplStud  
polypeptide Q80WJ6 UniProt | EBI | MGI Sequence Detail 1366 Not Applicable  
For the selected sequence
Protein
Information
less
  • UniProt
    4 Sequences
  • Protein Ontology
    PR:000003557 ATP-binding cassette sub-family C member 12
    (term hierarchy)
  • InterPro Domains
    IPR003593 AAA+ ATPase domain
    IPR003439 ABC transporter-like, ATP-binding domain
    IPR017871 ABC transporter-like, conserved site
    IPR011527 ABC transporter type 1, transmembrane domain
    IPR036640 ABC transporter type 1, transmembrane domain superfamily
    IPR050173 ATP-binding cassette transporter C
    IPR027417 P-loop containing nucleoside triphosphate hydrolase
  • GlyGen
    Q80WJ6 2 sites
Molecular
Reagents
less
  • All nucleic 21
    cDNA 18
    Primer pair 2
    Other 1

    Microarray probesets 3
References
more
  • Summaries
    All 67
    Developmental Gene Expression 2
    Gene Ontology 8
    Phenotypes 35
  • Earliest
    J:13049 Gruneberg H, Genetical studies on the skeleton of the mouse. XVIII. Three genes for syndactylism. J Genet. 1956;54(1):113-145
  • Latest
    J:345621 Adams DJ, et al., Genetic determinants of micronucleus formation in vivo. Nature. 2024 Mar;627(8002):130-136
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
12/10/2024
MGI 6.24 		The Jackson Laboratory