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Adgrg7 Gene Detail
Summary
  • Symbol
    Adgrg7
  • Name
    adhesion G protein-coupled receptor G7
  • Synonyms
    9130020O16Rik, Gpr128
  • Feature Type
    protein coding gene
  • IDs
    MGI:2441732
    NCBI Gene: 239853
  • Alliance
  • Transcription Start Sites
    1 TSS
Location &
Maps
more
  • Sequence Map
    Chr16:56544972-56616218 bp, - strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
  • Genetic Map
    Chromosome 16, 34.22 cM
  • Mapping Data
    1 experiment
Strain
Comparison
more
  • SNPs within 2kb
    2135 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_2441732
protein coding gene Chr16:56544972-56616369 (-)
129S1/SvImJ MGP_129S1SvImJ_G0022891
protein coding gene Chr16:55859172-55938528 (-)
A/J MGP_AJ_G0022858
protein coding gene Chr16:53455251-53542196 (-)
AKR/J MGP_AKRJ_G0022830
protein coding gene Chr16:55145494-55226930 (-)
BALB/cJ MGP_BALBcJ_G0022858
protein coding gene Chr16:53559892-53630194 (-)
C3H/HeJ MGP_C3HHeJ_G0022621
protein coding gene Chr16:55338259-55418838 (-)
C57BL/6NJ MGP_C57BL6NJ_G0023306
protein coding gene Chr16:57447581-57515239 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0020817
protein coding gene Chr16:53136641-53202277 (-)
CAST/EiJ MGP_CASTEiJ_G0022148
protein coding gene Chr16:55729617-55808585 (-)
CBA/J MGP_CBAJ_G0022594
protein coding gene Chr16:59737795-59817099 (-)
DBA/2J MGP_DBA2J_G0022726
protein coding gene Chr16:53216710-53285248 (-)
FVB/NJ MGP_FVBNJ_G0022701
protein coding gene Chr16:52981511-53050741 (-)
LP/J MGP_LPJ_G0022793
protein coding gene Chr16:55675071-55757714 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0022719
protein coding gene Chr16:60076495-60156708 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0023321
protein coding gene Chr16:55322625-55394122 (-)
PWK/PhJ MGP_PWKPhJ_G0021887
protein coding gene Chr16:53538329-53612035 (-)
SPRET/EiJ MGP_SPRETEiJ_G0021717
protein coding gene Chr16:55072697-55144221 (-)
WSB/EiJ MGP_WSBEiJ_G0022192
protein coding gene Chr16:55343820-55419168 (-)



Homology
more
  • Human Ortholog
    ADGRG7, adhesion G protein-coupled receptor G7
  • Vertebrate Orthologs
    4
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    ADGRG7, adhesion G protein-coupled receptor G7
  • Synonyms
    GPR128
  • Links
    NCBI Gene ID: 84873
    neXtProt AC: NX_Q96K78
    UniProt: Q96K78

  • Chr Location
    3q12.2; chr3:100609601-100695479 (+)  GRCh38

Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    6 phenotypes from 2 alleles in 2 genetic backgrounds
    9 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Mice homozygous for a knock-out allele exhibit reduced body weight gain and increased frequency of peristalsis and slow wave potential in the small intestine.
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
  • Comparison Matrix
  • Sequences &
    Gene Models
    less
    Representative SequencesLengthStrain/SpeciesFlank
    genomic ENSMUSG00000022755 Ensembl Gene Model | MGI Sequence Detail 71247 C57BL/6J ±  kb
    transcript ENSMUST00000023437 Ensembl | MGI Sequence Detail 2698 Not Applicable  
    polypeptide ENSMUSP00000023437 Ensembl | MGI Sequence Detail 785 Not Applicable  
    For the selected sequence
    Protein
    Information
    less
    Molecular
    Reagents
    less
    • All nucleic 4
      cDNA 4

      Microarray probesets 1
    References
    more
    • Summaries
      All 28
      Developmental Gene Expression 1
      Gene Ontology 4
      Phenotypes 9
    • Earliest
      J:80000 The FANTOM Consortium and The RIKEN Genome Exploration Research Group Phase I & II Team, Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs. Nature. 2002;420:563-573
    • Latest
      J:345621 Adams DJ, et al., Genetic determinants of micronucleus formation in vivo. Nature. 2024 Mar;627(8002):130-136

    Contributing Projects:
    Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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    Funding Information
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    last database update
    12/10/2024
    MGI 6.24
    The Jackson Laboratory