About   Help   FAQ
Fchsd1 Gene Detail
Summary
  • Symbol
    Fchsd1
  • Name
    FCH and double SH3 domains 1
  • Synonyms
    A030002D08Rik
  • Feature Type
    protein coding gene
  • IDs
    MGI:2441771
    NCBI Gene: 319262
  • Alliance
    gene page
  • Transcription Start Sites
    2 TSS
Location &
Maps
more
  • Sequence Map
    Chr18:38090484-38102827 bp, - strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 18, 19.84 cM
  • Mapping Data
    1 experiment
Strain
Comparison
more
  • SNPs within 2kb
    329 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_2441771
 protein coding gene Chr18:38090484-38102828 (-)
129S1/SvImJ MGP_129S1SvImJ_G0024357
 protein coding gene Chr18:36380099-36392441 (-)
A/J MGP_AJ_G0024324
 protein coding gene Chr18:35127131-35139472 (-)
AKR/J MGP_AKRJ_G0024293
 protein coding gene Chr18:36090035-36102377 (-)
BALB/cJ MGP_BALBcJ_G0024324
 protein coding gene Chr18:35193488-35205829 (-)
C3H/HeJ MGP_C3HHeJ_G0024090
 protein coding gene Chr18:36156265-36168636 (-)
C57BL/6NJ MGP_C57BL6NJ_G0024766
 protein coding gene Chr18:37679633-37691970 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0022205
 protein coding gene Chr18:35147258-35159762 (-)
CAST/EiJ MGP_CASTEiJ_G0023565
 protein coding gene Chr18:36097136-36109419 (-)
CBA/J MGP_CBAJ_G0024060
 protein coding gene Chr18:38792866-38805206 (-)
DBA/2J MGP_DBA2J_G0024190
 protein coding gene Chr18:34727623-34739961 (-)
FVB/NJ MGP_FVBNJ_G0024156
 protein coding gene Chr18:34437981-34450326 (-)
LP/J MGP_LPJ_G0024274
 protein coding gene Chr18:36443944-36456284 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0024187
 protein coding gene Chr18:40045822-40058195 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0024815
 protein coding gene Chr18:35955159-35967491 (-)
PWK/PhJ MGP_PWKPhJ_G0023309
 protein coding gene Chr18:34936756-34949154 (-)
SPRET/EiJ MGP_SPRETEiJ_G0023114
 protein coding gene Chr18:36171828-36184162 (-)
WSB/EiJ MGP_WSBEiJ_G0023628
 protein coding gene Chr18:35855402-35867747 (-)



Homology
more
  • Human Ortholog
    FCHSD1, FCH and double SH3 domains 1
  • Vertebrate Orthologs
    2
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    FCHSD1, FCH and double SH3 domains 1
  • Synonyms
    NWK2
  • Links
    NCBI Gene ID: 89848
    neXtProt AC: NX_Q86WN1
    UniProt: Q86WN1

  • Chr Location
    5q31.3; chr5:141639302-141651418 (-)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    4 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    21
  • GO References
    6
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    706
  • cDNA Data
    5
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000038524 Ensembl Gene Model | MGI Sequence Detail 12344 C57BL/6J ±  kb
transcript ENSMUST00000043437 Ensembl | MGI Sequence Detail 4270 Not Applicable  
polypeptide ENSMUSP00000047878 Ensembl | MGI Sequence Detail 688 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 5
    cDNA 5

    Microarray probesets 2
References
more
  • Summaries
    All 25
    Gene Ontology 6
    Phenotypes 4
  • Earliest
    J:80000 The FANTOM Consortium and The RIKEN Genome Exploration Research Group Phase I & II Team, Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs. Nature. 2002;420:563-573
  • Latest
    J:343811 Kawasaki T, et al., Loss of FCHSD1 leads to amelioration of chronic obstructive pulmonary disease. Proc Natl Acad Sci U S A. 2021 Jun 29;118(26):e2019167118
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support. 		last database update
12/10/2024
MGI 6.24 		The Jackson Laboratory