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Gpr141b Gene Detail
Summary
  • Symbol
    Gpr141b
  • Name
    G protein-coupled receptor 141B
  • Synonyms
    A530099J19Rik, Karma
  • Feature Type
    protein coding gene
  • IDs
    MGI:2441809
    NCBI Gene: 319293
  • Alliance
    gene page
  • Transcription Start Sites
    3 TSS
Location &
Maps
more
  • Sequence Map
    Chr13:19911596-19917121 bp, - strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 13, 7.03 cM
  • Mapping Data
    1 experiment
Strain
Comparison
more
  • SNPs within 2kb
    264 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_2441809
 protein coding gene Chr13:19911587-19917125 (-)
129S1/SvImJ MGP_129S1SvImJ_G0020262
 protein coding gene Chr13:16915484-16921008 (-)
A/J MGP_AJ_G0020219
 protein coding gene Chr13:16631830-16637358 (-)
AKR/J MGP_AKRJ_G0020193
 protein coding gene Chr13:16843004-16848540 (-)
BALB/cJ MGP_BALBcJ_G0020205
 protein coding gene Chr13:16664397-16669925 (-)
C3H/HeJ MGP_C3HHeJ_G0020008
 protein coding gene Chr13:16964192-16969728 (-)
C57BL/6NJ MGP_C57BL6NJ_G0020649
 protein coding gene Chr13:17558992-17564526 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0018256
 protein coding gene Chr13:15070092-15075583 (-)
CAST/EiJ MGP_CASTEiJ_G0019543
 protein coding gene Chr13:16712188-16717749 (-)
CBA/J MGP_CBAJ_G0019972
 protein coding gene Chr13:18170120-18175656 (-)
DBA/2J MGP_DBA2J_G0020091
 protein coding gene Chr13:16229027-16234563 (-)
FVB/NJ MGP_FVBNJ_G0020073
 protein coding gene Chr13:15911729-15917257 (-)
LP/J MGP_LPJ_G0020162
 protein coding gene Chr13:17158343-17163879 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0020111
 protein coding gene Chr13:18614061-18619597 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0020678
 protein coding gene Chr13:16666779-16672313 (-)
PWK/PhJ MGP_PWKPhJ_G0019306
 protein coding gene Chr13:16281141-16286698 (-)
SPRET/EiJ MGP_SPRETEiJ_G0019112
 protein coding gene Chr13:15727757-15733280 (-)
WSB/EiJ MGP_WSBEiJ_G0019602
 protein coding gene Chr13:16721030-16726553 (-)



Homology
more
  • Human Ortholog
    GPR141BP, G protein-coupled receptor 141B, pseudogene
  • Vertebrate Orthologs
    1
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    GPR141BP, G protein-coupled receptor 141B, pseudogene
  • Links
    NCBI Gene ID: 100420413

  • Chr Location
    chr7:37796058-37796888 (+)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    2 phenotypes from 1 allele in 1 genetic background
    19 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    1
  • GO References
    1
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

No experimental evidence to support Cellular Component annotation, following literature review. See J:73796.
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    706
  • cDNA Data
    4
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000047462 Ensembl Gene Model | MGI Sequence Detail 5526 C57BL/6J ±  kb
transcript ENSMUST00000151029 Ensembl | MGI Sequence Detail 2764 Not Applicable  
polypeptide ENSMUSP00000158601 Ensembl | MGI Sequence Detail 299 Not Applicable  
For the selected sequence
Protein
Information
less
  • UniProt
    2 Sequences
  • InterPro Domains
    IPR017452 GPCR, rhodopsin-like, 7TM
    IPR047160 G-protein coupled receptor 183-like
    IPR000276 G protein-coupled receptor, rhodopsin-like
Molecular
Reagents
less
  • All nucleic 4
    cDNA 4

    Microarray probesets 1
Other
Accession IDs
less
MGI:6159590
References
more
  • Summaries
    All 33
    Gene Ontology 1
    Phenotypes 19
  • Earliest
    J:71411 Arkell RM, et al., Genetic, physical, and phenotypic characterization of the Del(13)Svea36H mouse. Mamm Genome. 2001 Sep;12(9):687-94
  • Latest
    J:345621 Adams DJ, et al., Genetic determinants of micronucleus formation in vivo. Nature. 2024 Mar;627(8002):130-136
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
11/19/2024
MGI 6.24 		The Jackson Laboratory