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Hmgxb3 Gene Detail
Summary
  • Symbol
    Hmgxb3
  • Name
    HMG box domain containing 3
  • Synonyms
    2510002C16Rik, A630042L21Rik, mKIAA0194
  • Feature Type
    protein coding gene
  • IDs
    MGI:2441817
    NCBI Gene: 106894
  • Alliance
  • Transcription Start Sites
    2 TSS
Location &
Maps
more
  • Sequence Map
    Chr18:61264349-61310122 bp, - strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
  • Genetic Map
    Chromosome 18, 34.41 cM
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    1193 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_2441817
protein coding gene Chr18:61264349-61310122 (-)
129S1/SvImJ MGP_129S1SvImJ_G0024476
protein coding gene Chr18:60990157-61040989 (-)
A/J MGP_AJ_G0024443
protein coding gene Chr18:58378764-58425366 (-)
AKR/J MGP_AKRJ_G0024413
protein coding gene Chr18:59987443-60033919 (-)
BALB/cJ MGP_BALBcJ_G0024442
protein coding gene Chr18:58509576-58555862 (-)
C3H/HeJ MGP_C3HHeJ_G0024210
protein coding gene Chr18:60213550-60260011 (-)
C57BL/6NJ MGP_C57BL6NJ_G0024889
protein coding gene Chr18:62644287-62689995 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0022320
protein coding gene Chr18:57925622-57971740 (-)
CAST/EiJ MGP_CASTEiJ_G0023683
protein coding gene Chr18:60084849-60131143 (-)
CBA/J MGP_CBAJ_G0024180
protein coding gene Chr18:64648826-64699110 (-)
DBA/2J MGP_DBA2J_G0024310
protein coding gene Chr18:58047678-58093677 (-)
FVB/NJ MGP_FVBNJ_G0024276
protein coding gene Chr18:57456723-57502947 (-)
LP/J MGP_LPJ_G0024393
protein coding gene Chr18:60840782-60886452 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0024305
protein coding gene Chr18:66282450-66330086 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0024936
protein coding gene Chr18:60178814-60225069 (-)
PWK/PhJ MGP_PWKPhJ_G0023426
protein coding gene Chr18:58277240-58323901 (-)
SPRET/EiJ MGP_SPRETEiJ_G0023232
protein coding gene Chr18:60407868-60455996 (-)
WSB/EiJ MGP_WSBEiJ_G0023747
protein coding gene Chr18:60034758-60081601 (-)



Homology
more
  • Human Ortholog
    HMGXB3, HMG-box containing 3
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    HMGXB3, HMG-box containing 3
  • Synonyms
    HMGX3, SMF
  • Links
    NCBI Gene ID: 22993
    neXtProt AC: NX_Q12766
    UniProt: Q12766

  • Chr Location
    5q32; chr5:150000046-150053142 (+)  GRCh38

Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    15 phenotypes from 1 allele in 1 genetic background
    11 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Gene Ontology
(GO)
Classifications
less
Molecular Function

No experimental evidence to support Molecular Function annotation, following literature review. See J:73796.
Biological Process

No experimental evidence to support Biological Process annotation, following literature review. See J:73796.
Cellular Component

No experimental evidence to support Cellular Component annotation, following literature review. See J:73796.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
  • Comparison Matrix
  • Sequences &
    Gene Models
    less
    Representative SequencesLengthStrain/SpeciesFlank
    genomic 106894 NCBI Gene Model | MGI Sequence Detail 45774 C57BL/6J ±  kb
    transcript NM_178277 RefSeq | MGI Sequence Detail 5211 C57BL/6  
    polypeptide NP_840061 RefSeq | MGI Sequence Detail 1286 C57BL/6  
    For the selected sequence
    Protein
    Information
    less
    • UniProt
      11 Sequences
    • InterPro Domains
      IPR009071 High mobility group box domain
      IPR036910 High mobility group box domain superfamily
      IPR039598 HMG domain-containing protein 3
      IPR040648 HMG domain-containing protein 3, CxC4 like cysteine cluster
    Molecular
    Reagents
    less
    • All nucleic 19
      cDNA 18
      Primer pair 1

      Microarray probesets 3
    Other
    Accession IDs
    less
    MGI:1919564, MGI:2147216
    References
    more
    • Summaries
      All 39
      Developmental Gene Expression 5
      Phenotypes 11
    • Earliest
      J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
    • Latest
      J:345621 Adams DJ, et al., Genetic determinants of micronucleus formation in vivo. Nature. 2024 Mar;627(8002):130-136

    Contributing Projects:
    Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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    last database update
    12/10/2024
    MGI 6.24
    The Jackson Laboratory