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Qrfprl Gene Detail
Summary
  • Symbol
    Qrfprl
  • Name
    pyroglutamylated RFamide peptide receptor like
  • Synonyms
    C130060K24Rik, Gpr103b
  • Feature Type
    protein coding gene
  • IDs
    MGI:2441881
    NCBI Gene: 243407
  • Alliance
    gene page
Location &
Maps
more
  • Sequence Map
    Chr6:65358278-65435134 bp, + strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 6, 30.19 cM
  • Mapping Data
    1 experiment
Strain
Comparison
more
  • SNPs within 2kb
    1961 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_2441881
 protein coding gene Chr6:65358089-65435134 (+)
129S1/SvImJ MGP_129S1SvImJ_G0030831
 protein coding gene Chr6:65289348-65375253 (+)
A/J MGP_AJ_G0030798
 protein coding gene Chr6:62454982-62528282 (+)
AKR/J MGP_AKRJ_G0030726
 protein coding gene Chr6:64413159-64484814 (+)
BALB/cJ MGP_BALBcJ_G0030809
 protein coding gene Chr6:62853743-62925846 (+)
C3H/HeJ MGP_C3HHeJ_G0030903
 protein coding gene Chr6:119706980-119783545 (-)
C57BL/6NJ MGP_C57BL6NJ_G0031267
 protein coding gene Chr6:66820727-66898626 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0028460
 protein coding gene Chr6:59766466-59833287 (+)
CAST/EiJ MGP_CASTEiJ_G0029921
 protein coding gene Chr6:64691259-64763117 (+)
CBA/J MGP_CBAJ_G0030496
 protein coding gene Chr6:69533150-69615604 (+)
DBA/2J MGP_DBA2J_G0030648
 protein coding gene Chr6:62153405-62222708 (+)
FVB/NJ MGP_FVBNJ_G0030601
 protein coding gene Chr6:61681366-61748020 (+)
LP/J MGP_LPJ_G0030732
 protein coding gene Chr6:65231392-65305708 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0030636
 protein coding gene Chr6:73298436-73376474 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0031293
 protein coding gene Chr6:64372674-64453704 (+)
PWK/PhJ MGP_PWKPhJ_G0029636
 protein coding gene Chr6:61290629-61360967 (+)
SPRET/EiJ MGP_SPRETEiJ_G0029464
 protein coding gene Chr6:63896485-63979640 (+)
WSB/EiJ MGP_WSBEiJ_G0030003
 protein coding gene Chr6:64660180-64736739 (+)



Homology
more
  • Human Ortholog
    QRFPR, pyroglutamylated RFamide peptide receptor
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    QRFPR, pyroglutamylated RFamide peptide receptor
  • Synonyms
    AQ27, GPR103, SP9155
  • Links
    NCBI Gene ID: 84109
    neXtProt AC: NX_Q96P65
    UniProt: Q96P65

  • Chr Location
    4q27; chr4:121328642-121381059 (-)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    1 phenotype reference
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    6
  • GO References
    2
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    800
  • Tissues
    94
  • cDNA Data
    5
  • Literature Summary
    1
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic 243407 NCBI Gene Model | MGI Sequence Detail 76857 C57BL/6J ±  kb
transcript NM_175524 RefSeq | MGI Sequence Detail 2953 C57BL/6  
polypeptide NP_780733 RefSeq | MGI Sequence Detail 416 C57BL/6  
For the selected sequence
Protein
Information
less
  • UniProt
    6 Sequences
  • InterPro Domains
    IPR017452 GPCR, rhodopsin-like, 7TM
    IPR000276 G protein-coupled receptor, rhodopsin-like
    IPR000611 Neuropeptide Y receptor family
Molecular
Reagents
less
  • All nucleic 7
    cDNA 5
    Primer pair 1
    Other 1

    Microarray probesets 1
Other
Accession IDs
less
MGI:6304964
References
more
  • Summaries
    All 16
    Developmental Gene Expression 1
    Gene Ontology 2
    Phenotypes 1
  • Earliest
    J:80000 The FANTOM Consortium and The RIKEN Genome Exploration Research Group Phase I & II Team, Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs. Nature. 2002;420:563-573
  • Latest
    J:355747 Cook C, et al., The hypothalamic RFamide, QRFP, increases feeding and locomotor activity: The role of Gpr103 and orexin receptors. PLoS One. 2022;17(10):e0275604
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
12/10/2024
MGI 6.24 		The Jackson Laboratory