Caps2 Gene Detail

Summary

• Symbol
  Caps2
• Name
  calcyphosphine 2
• Synonyms
  D630005B03Rik

• Feature Type
  protein coding gene
• IDs
  MGI:2441980
  NCBI Gene: 353025
• Alliance
  gene page

Location &
Maps

• Sequence Map
  Chr10:111999526-112052460 bp, + strand

  From Ensembl annotation of GRCm39
  

• View this region in JBrowse
  

• Genome Browsers
  Ensembl | UCSC | NCBI

• Genetic Map
  Chromosome 10, 60.18 cM
• Mapping Data
  2 experiments

Strain
Comparison

• SNPs within 2kb
  1899 from dbSNP Build 142
• Strain Annotations
  12

Strain	Gene Model ID	Feature Type	Coordinates
C57BL/6J	MGI_C57BL6J_2441980	protein coding gene	Chr10:111999254-112052466 (+)
129S1/SvImJ	MGP_129S1SvImJ_G0017727	protein coding gene	Chr10:114670606-114732960 (+)
A/J	MGP_AJ_G0017704	protein coding gene	Chr10:110305024-110378983 (+)
AKR/J	MGP_AKRJ_G0017666	protein coding gene	Chr10:113523287-113626022 (+)
BALB/cJ	no annotation
C3H/HeJ	no annotation
C57BL/6NJ	no annotation
CAROLI/EiJ	MGP_CAROLIEiJ_G0015804	protein coding gene	Chr10:105098340-105143359 (+)
CAST/EiJ	MGP_CASTEiJ_G0017052	protein coding gene	Chr10:113732822-113952532 (+)
CBA/J	no annotation
DBA/2J	no annotation
FVB/NJ	MGP_FVBNJ_G0017561	protein coding gene	Chr10:108419794-108487995 (+)
LP/J	MGP_LPJ_G0017641	protein coding gene	Chr10:115322631-115387090 (+)
NOD/ShiLtJ	MGP_NODShiLtJ_G0017590	protein coding gene	Chr10:125842542-125930654 (+)
NZO/HlLtJ	no annotation
PWK/PhJ	MGP_PWKPhJ_G0016836	protein coding gene	Chr10:109479979-109570682 (+)
SPRET/EiJ	MGP_SPRETEiJ_G0016626	protein coding gene	Chr10:112291392-112372888 (+)
WSB/EiJ	MGP_WSBEiJ_G0017114	protein coding gene	Chr10:113722457-113779979 (+)

Homology

• Human Ortholog
  CAPS2, calcyphosine 2

• Vertebrate Orthologs
  3

Vertebrate Orthology Source

Alliance of Genome Resources

• Human Ortholog
  CAPS2, calcyphosine 2
  
• Synonyms
  UG0636c06
• Links
  HGNC:16471

  NCBI Gene ID: 84698

  neXtProt AC: NX_Q9BXY5

  UniProt: Q9BXY5

  
  
• Chr Location
  12q21.1-q21.2; chr12:75275979-75390928 (-)  GRCh38

---

• MGI Vertebrate Homology
  Caps2 stringent orthology
  1 human;1 mouse;1 rat;1 zebrafish
  
• HCOP
  vertebrate homology predictions: CAPS2
• Gene Tree
  Caps2
  

Mutations,
Alleles, and
Phenotypes

• Phenotype Summary
  9 phenotype references
  

• All Mutations and Alleles
  5
• Chemically induced (other)
  1
• Endonuclease-mediated
  1
• Targeted
  3
• Genomic Mutations
  1 involving Caps2
• Incidental Mutations
  Mutagenetix , APF , CvDC
• Find Mice (IMSR)
  28 strains or lines available

Gene Ontology
(GO)
Classifications

• All GO Annotations
  1
• GO References
  1

Expression

• Assay Results
  706
• cDNA Data
  5

Tissue x Stage Matrix

• Other Mouse Links
  Allen Institute
  GEO
  Expression Atlas
• Other Vertebrate Links
  Xenbase caps2

Sequences &
Gene Models

• All Sequences
  52
• RefSeq
  27
• UniProt
  2
• CCDS
  CCDS24172.2, CCDS78896.1

• Ensembl
  ENSMUSG00000035694 (Evidence)
• NCBI Gene
  353025

Representative Sequences			Length	Strain/Species
genomic	ENSMUSG00000035694	Ensembl Gene Model | MGI Sequence Detail	52935	C57BL/6J
transcript	ENSMUST00000170013	Ensembl | MGI Sequence Detail	2321	Not Applicable
polypeptide	ENSMUSP00000129887	Ensembl | MGI Sequence Detail	592	Not Applicable

Protein
Information

• UniProt
  2 Sequences
• Protein Ontology
  PR:000005027 calcyphosin-2
  (term hierarchy)
• InterPro Domains
  IPR051581 Calcium-Binding Signaling
  IPR018247 EF-Hand 1, calcium-binding site
  IPR002048 EF-hand domain
  IPR011992 EF-hand domain pair

Molecular
Reagents

• All nucleic 6

  cDNA 6

  
  

  Microarray probesets 3

References

• Summaries
  All 39

  Gene Ontology 1

  Phenotypes 9
• Earliest
  J:137335 Roderick TH, Chromosomal inversions in studies of mammalian mutagenesis. Genetics. 1979 May;92(1 Pt 1 Suppl):s121-6
• Latest
  J:310161 Fujima S, et al., CAPS2 Deficiency Impairs the Release of the Social Peptide Oxytocin, as Well as Oxytocin-Associated Social Behavior. J Neurosci. 2021 May 19;41(20):4524-4535