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Gpr157 Gene Detail
Summary
  • Symbol
    Gpr157
  • Name
    G protein-coupled receptor 157
  • Synonyms
    F730108M23Rik
  • Feature Type
    protein coding gene
  • IDs
    MGI:2442046
    NCBI Gene: 269604
  • Alliance
    gene page
  • Transcription Start Sites
    3 TSS
Location &
Maps
more
  • Sequence Map
    Chr4:150171960-150190457 bp, + strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 4, 80.89 cM
  • Mapping Data
    1 experiment
Strain
Comparison
more
  • SNPs within 2kb
    238 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_2442046
 protein coding gene Chr4:150171822-150190457 (+)
129S1/SvImJ MGP_129S1SvImJ_G0029149
 protein coding gene Chr4:154012467-154032500 (+)
A/J MGP_AJ_G0029114
 protein coding gene Chr4:147565582-147584625 (+)
AKR/J MGP_AKRJ_G0029062
 protein coding gene Chr4:151621249-151639790 (+)
BALB/cJ MGP_BALBcJ_G0029130
 protein coding gene Chr4:148064000-148082839 (+)
C3H/HeJ MGP_C3HHeJ_G0028851
 protein coding gene Chr4:152152952-152171492 (+)
C57BL/6NJ MGP_C57BL6NJ_G0029579
 protein coding gene Chr4:159562317-159582079 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0026825
 protein coding gene Chr4:139972678-139991771 (+)
CAST/EiJ MGP_CASTEiJ_G0028264
 protein coding gene Chr4:149405985-149423752 (+)
CBA/J MGP_CBAJ_G0028813
 protein coding gene Chr4:164262454-164280793 (+)
DBA/2J MGP_DBA2J_G0028962
 protein coding gene Chr4:147659592-147678439 (+)
FVB/NJ MGP_FVBNJ_G0028926
 protein coding gene Chr4:146787933-146806540 (+)
LP/J MGP_LPJ_G0029052
 protein coding gene Chr4:153942755-153961396 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0028953
 protein coding gene Chr4:167430897-167449439 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0029611
 protein coding gene Chr4:152117379-152135919 (+)
PWK/PhJ MGP_PWKPhJ_G0027984
 protein coding gene Chr4:143681858-143701337 (+)
SPRET/EiJ MGP_SPRETEiJ_G0027818
 protein coding gene Chr4:146374751-146395311 (+)
WSB/EiJ MGP_WSBEiJ_G0028344
 protein coding gene Chr4:152253810-152273587 (+)



Homology
more
  • Human Ortholog
    GPR157, G protein-coupled receptor 157
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    GPR157, G protein-coupled receptor 157
  • Links
    NCBI Gene ID: 80045
    neXtProt AC: NX_Q5UAW9
    UniProt: Q5UAW9

  • Chr Location
    1p36.22; chr1:9100305-9129102 (-)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    8 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    9
  • GO References
    3
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    768
  • Tissues
    58
  • cDNA Data
    12
  • Literature Summary
    2
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic 269604 NCBI Gene Model | MGI Sequence Detail 18498 C57BL/6J ±  kb
transcript NM_177366 RefSeq | MGI Sequence Detail 4762 C57BL/6  
polypeptide Q8C206 UniProt | EBI | MGI Sequence Detail 330 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 13
    cDNA 12
    Primer pair 1

    Microarray probesets 1
References
more
  • Summaries
    All 26
    Developmental Gene Expression 2
    Gene Ontology 3
    Phenotypes 8
  • Earliest
    J:80000 The FANTOM Consortium and The RIKEN Genome Exploration Research Group Phase I & II Team, Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs. Nature. 2002;420:563-573
  • Latest
    J:345621 Adams DJ, et al., Genetic determinants of micronucleus formation in vivo. Nature. 2024 Mar;627(8002):130-136
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
11/12/2024
MGI 6.24 		The Jackson Laboratory