Fcgbpl1 Gene Detail

Summary

• Symbol
  Fcgbpl1
• Name
  Fc fragment of IgG binding protein like 1
• Synonyms
  9530053A07Rik

• Feature Type
  protein coding gene
• IDs
  MGI:2442118
  NCBI Gene: 319482
• Alliance
  gene page
• Transcription Start Sites
  74 TSS

Location &
Maps

• Sequence Map
  Chr7:27828891-27864236 bp, + strand

  From NCBI annotation of GRCm39
  

• View this region in JBrowse
  

• Genome Browsers
  Ensembl | UCSC | NCBI

• Genetic Map
  Chromosome 7, 16.54 cM
• Mapping Data
  1 experiment

Strain
Comparison

• SNPs within 2kb
  861 from dbSNP Build 142
• Strain Annotations
  18

Strain	Gene Model ID	Feature Type	Coordinates
C57BL/6J	MGI_C57BL6J_2442118	protein coding gene	Chr7:27828891-27864236 (+)
129S1/SvImJ	MGP_129S1SvImJ_G0031931	protein coding gene	Chr7:26886505-26930519 (+)
A/J	MGP_AJ_G0031910	protein coding gene	Chr7:26228558-26281401 (+)
AKR/J	MGP_AKRJ_G0031841	protein coding gene	Chr7:26911056-26955839 (+)
BALB/cJ	MGP_BALBcJ_G0031916	protein coding gene	Chr7:26392982-26437482 (+)
C3H/HeJ	MGP_C3HHeJ_G0031638	protein coding gene	Chr7:27284255-27326257 (+)
C57BL/6NJ	MGP_C57BL6NJ_G0032381	protein coding gene	Chr7:27762696-27805171 (+)
CAROLI/EiJ	MGP_CAROLIEiJ_G0029433	protein coding gene	Chr7:27345524-27359170 (+)
CAST/EiJ	MGP_CASTEiJ_G0030973	protein coding gene	Chr7:20588370-20628652 (+)
CBA/J	MGP_CBAJ_G0031601	protein coding gene	Chr7:28997460-29044929 (+)
DBA/2J	MGP_DBA2J_G0031754	protein coding gene	Chr7:26006374-26044838 (+)
FVB/NJ	MGP_FVBNJ_G0031711	protein coding gene	Chr7:26081217-26118704 (+)
LP/J	MGP_LPJ_G0031835	protein coding gene	Chr7:27210859-27257114 (+)
NOD/ShiLtJ	MGP_NODShiLtJ_G0031746	protein coding gene	Chr7:28517700-28558834 (+)
NZO/HlLtJ	MGP_NZOHlLtJ_G0032411	protein coding gene	Chr7:26374614-26416578 (+)
PWK/PhJ	MGP_PWKPhJ_G0030696	protein coding gene	Chr7:21014728-21029589 (+)
SPRET/EiJ	MGP_SPRETEiJ_G0030531	protein coding gene	Chr7:17384805-17398360 (+)
WSB/EiJ	MGP_WSBEiJ_G0031080	protein coding gene	Chr7:26718793-26735898 (+)

Homology

• Human Ortholog
  FCGBP, Fc gamma binding protein

• Vertebrate Orthologs
  3

Vertebrate Orthology Source

Alliance of Genome Resources

• Human Ortholog
  FCGBP, Fc gamma binding protein
  
• Synonyms
  FC(GAMMA)BP
• Links
  HGNC:13572

  NCBI Gene ID: 8857

  neXtProt AC: NX_Q9Y6R7

  UniProt: Q9Y6R7

  
  
• Chr Location
  19q13.2; chr19:39863323-39934634 (-)  GRCh38

---

• MGI Vertebrate Homology
  Fcgbpl1 stringent orthology
  1 human;1 mouse;1 rat;1 zebrafish
  
• HCOP
  vertebrate homology predictions: FCGBP
• Gene Tree
  Fcgbpl1
  

Mutations,
Alleles, and
Phenotypes

• Phenotype Summary
  1 phenotype reference
  

• All Mutations and Alleles
  2
• Targeted
  2
• Incidental Mutations
  Mutagenetix , APF , CvDC
• Find Mice (IMSR)
  116 strains or lines available

Gene Ontology
(GO)
Classifications

• All GO Annotations
  2
• GO References
  1

Expression

• Assay Results
  706
• cDNA Data
  9

Tissue x Stage Matrix

• Other Mouse Links
  Allen Institute
  GEO
  Expression Atlas

Sequences &
Gene Models

• All Sequences
  38
• RefSeq
  2
• UniProt
  4
• CCDS
  CCDS21035.1, CCDS52160.1

• Ensembl
  ENSMUSG00000078776 (Evidence)
• NCBI Gene
  319482

Representative Sequences			Length	Strain/Species
genomic	319482	NCBI Gene Model | MGI Sequence Detail	35346	C57BL/6J
transcript	NM_001164655	RefSeq | MGI Sequence Detail	7922	Not Specified
polypeptide	NP_001158127	RefSeq | MGI Sequence Detail	2581	Not Specified

Protein
Information

• UniProt
  4 Sequences
• InterPro Domains
  IPR052749 Alpha-tectorin
  IPR003645 Follistatin-like, N-terminal
  IPR050780 Mucin/von Willebrand/Thrombospondin superfamily
  IPR036084 Serine protease inhibitor-like superfamily
  IPR025615 TILa domain
  IPR002919 Trypsin Inhibitor-like, cysteine rich domain
  IPR001846 von Willebrand factor, type D domain
  IPR001007 VWFC domain
  IPR014853 VWF/SSPO/Zonadhesin-like, cysteine-rich domain
• GlyGen
  E9PVG8 4 sites, 3 N-linked glycans (3 sites), 1 O-linked glycan (1 site)

Molecular
Reagents

• All nucleic 11

  cDNA 9

  Other 2

Other
Accession IDs

MGI:7414205

References

• Summaries
  All 15

  Gene Ontology 1

  Phenotypes 1
• Earliest
  J:80000 The FANTOM Consortium and The RIKEN Genome Exploration Research Group Phase I & II Team, Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs. Nature. 2002;420:563-573
• Latest
  J:150756 Johansson ME, et al., Proteomic analyses of the two mucus layers of the colon barrier reveal that their main component, the muc2 mucin, is strongly bound to the fcgbp protein. J Proteome Res. 2009 Jul;8(7):3549-57

TSS for Fcgbpl1:

(View these features in JBrowse)

Transcription Start Site	Location	Distance from Gene 5'-end
Tssr65372	Chr7:27828527-27828531 (+)	-362 bp
Tssr65373	Chr7:27828567-27828607 (+)	-304 bp
Tssr65374	Chr7:27828803-27828813 (+)	-83 bp
Tssr65375	Chr7:27828856-27828883 (+)	-21 bp
Tssr65376	Chr7:27828884-27828904 (+)	3 bp
Tssr65377	Chr7:27828905-27828915 (+)	19 bp
Tssr65378	Chr7:27828937-27828938 (+)	47 bp
Tssr65379	Chr7:27829061-27829063 (+)	171 bp
Tssr65380	Chr7:27829229-27829235 (+)	341 bp
Tssr65381	Chr7:27830913-27830928 (+)	2,030 bp
Tssr65382	Chr7:27830966-27830981 (+)	2,083 bp
Tssr65383	Chr7:27831080-27831087 (+)	2,193 bp
Tssr65384	Chr7:27831121-27831132 (+)	2,236 bp
Tssr65385	Chr7:27834480-27834483 (+)	5,591 bp
Tssr65386	Chr7:27836529-27836536 (+)	7,642 bp
Tssr65387	Chr7:27836858-27836869 (+)	7,973 bp
Tssr65388	Chr7:27836955-27836967 (+)	8,070 bp
Tssr65389	Chr7:27837011-27837021 (+)	8,125 bp
Tssr65390	Chr7:27839147-27839171 (+)	10,268 bp
Tssr65391	Chr7:27839178-27839183 (+)	10,290 bp
Tssr65392	Chr7:27839200-27839220 (+)	10,319 bp
Tssr65393	Chr7:27839338-27839346 (+)	10,451 bp
Tssr65394	Chr7:27839387-27839396 (+)	10,501 bp
Tssr65395	Chr7:27839502-27839508 (+)	10,614 bp
Tssr2159	Chr7:27839567-27839575 (+)	10,680 bp
Tssr65396	Chr7:27839589-27839590 (+)	10,699 bp
Tssr65397	Chr7:27839594-27839604 (+)	10,708 bp
Tssr65398	Chr7:27839608-27839614 (+)	10,720 bp
Tssr65399	Chr7:27839620-27839641 (+)	10,740 bp
Tssr65400	Chr7:27840425-27840440 (+)	11,542 bp
Tssr2160	Chr7:27841645-27841659 (+)	12,761 bp
Tssr65401	Chr7:27841687-27841695 (+)	12,800 bp
Tssr65402	Chr7:27841710-27841727 (+)	12,828 bp
Tssr65403	Chr7:27841838-27841847 (+)	12,952 bp
Tssr65404	Chr7:27841871-27841881 (+)	12,985 bp
Tssr65405	Chr7:27841908-27841935 (+)	13,031 bp
Tssr65406	Chr7:27841987-27841998 (+)	13,102 bp
Tssr65407	Chr7:27842014-27842021 (+)	13,127 bp
Tssr65408	Chr7:27843282-27843289 (+)	14,395 bp
Tssr65409	Chr7:27843623-27843634 (+)	14,738 bp
Tssr65410	Chr7:27846450-27846457 (+)	17,563 bp
Tssr65411	Chr7:27846590-27846599 (+)	17,704 bp
Tssr65412	Chr7:27846847-27846855 (+)	17,960 bp
Tssr65413	Chr7:27852240-27852250 (+)	23,354 bp
Tssr65414	Chr7:27852341-27852355 (+)	23,457 bp
Tssr65415	Chr7:27852840-27852851 (+)	23,955 bp
Tssr65416	Chr7:27854001-27854004 (+)	25,112 bp
Tssr65417	Chr7:27854053-27854063 (+)	25,167 bp
Tssr65418	Chr7:27854065-27854076 (+)	25,180 bp
Tssr65419	Chr7:27854118-27854139 (+)	25,238 bp
Tssr65420	Chr7:27854145-27854155 (+)	25,259 bp
Tssr65421	Chr7:27854636-27854645 (+)	25,750 bp
Tssr65422	Chr7:27854659-27854669 (+)	25,773 bp
Tssr65423	Chr7:27856137-27856154 (+)	27,255 bp
Tssr65424	Chr7:27856155-27856159 (+)	27,266 bp
Tssr2161	Chr7:27856443-27856451 (+)	27,556 bp
Tssr65425	Chr7:27856494-27856499 (+)	27,606 bp
Tssr65426	Chr7:27856950-27856960 (+)	28,064 bp
Tssr65427	Chr7:27856973-27856989 (+)	28,090 bp
Tssr65428	Chr7:27856996-27857006 (+)	28,110 bp
Tssr65429	Chr7:27857009-27857019 (+)	28,123 bp
Tssr65430	Chr7:27857054-27857065 (+)	28,169 bp
Tssr65431	Chr7:27857071-27857079 (+)	28,184 bp
Tssr65432	Chr7:27857089-27857102 (+)	28,205 bp
Tssr65433	Chr7:27857206-27857214 (+)	28,319 bp
Tssr65434	Chr7:27857266-27857274 (+)	28,379 bp
Tssr65435	Chr7:27857413-27857421 (+)	28,526 bp
Tssr65436	Chr7:27858851-27858856 (+)	29,963 bp
Tssr65437	Chr7:27858905-27858919 (+)	30,021 bp
Tssr65438	Chr7:27860587-27860592 (+)	31,699 bp
Tssr65439	Chr7:27862148-27862149 (+)	33,258 bp
Tssr65440	Chr7:27862204-27862215 (+)	33,319 bp
Tssr65441	Chr7:27862289-27862300 (+)	33,404 bp
Tssr65442	Chr7:27864172-27864203 (+)	35,297 bp