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Zc3h12b Gene Detail
Summary
  • Symbol
    Zc3h12b
  • Name
    zinc finger CCCH-type containing 12B
  • Synonyms
    A130028J20Rik, LOC245523
  • Feature Type
    protein coding gene
  • IDs
    MGI:2442133
    NCBI Gene: 547176
  • Alliance
    gene page
  • Transcription Start Sites
    2 TSS
Location &
Maps
more
  • Sequence Map
    ChrX:94755284-94976243 bp, + strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome X, 42.14 cM
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    3689 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_2442133
 protein coding gene ChrX:94755206-94976262 (+)
129S1/SvImJ MGP_129S1SvImJ_G0035920
 protein coding gene ChrX:92052178-92283599 (+)
A/J MGP_AJ_G0035906
 protein coding gene ChrX:92267780-92481499 (+)
AKR/J MGP_AKRJ_G0035822
 protein coding gene ChrX:94684774-94920362 (+)
BALB/cJ MGP_BALBcJ_G0035890
 protein coding gene ChrX:91002379-91205576 (+)
C3H/HeJ MGP_C3HHeJ_G0035598
 protein coding gene ChrX:92575199-92778202 (+)
C57BL/6NJ MGP_C57BL6NJ_G0036419
 protein coding gene ChrX:94987506-95217622 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0033247
 protein coding gene ChrX:90302880-90485748 (+)
CAST/EiJ MGP_CASTEiJ_G0034884
 protein coding gene ChrX:77095184-77285745 (+)
CBA/J MGP_CBAJ_G0035573
 protein coding gene ChrX:97782604-98054945 (+)
DBA/2J MGP_DBA2J_G0035728
 protein coding gene ChrX:91430071-91671925 (+)
FVB/NJ MGP_FVBNJ_G0035666
 protein coding gene ChrX:90865186-91075856 (+)
LP/J MGP_LPJ_G0035818
 protein coding gene ChrX:93069257-93304158 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0035701
 protein coding gene ChrX:102118643-102356293 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0036446
 protein coding gene ChrX:91800498-92023482 (+)
PWK/PhJ MGP_PWKPhJ_G0034584
 protein coding gene ChrX:74745778-74954140 (+)
SPRET/EiJ MGP_SPRETEiJ_G0034413
 protein coding gene ChrX:77867018-78098826 (+)
WSB/EiJ MGP_WSBEiJ_G0035024
 protein coding gene ChrX:90656067-90864230 (+)



Homology
more
  • Human Ortholog
    ZC3H12B, zinc finger CCCH-type containing 12B
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    ZC3H12B, zinc finger CCCH-type containing 12B
  • Synonyms
    CXorf32, MCPIP2
  • Links
    NCBI Gene ID: 340554
    neXtProt AC: NX_Q5HYM0
    UniProt: Q5HYM0

  • Chr Location
    Xq11.2-q12; chrX:65034788-65507887 (+)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    6 phenotypes from 1 allele in 1 genetic background
    7 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    4
  • GO References
    1
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    706
  • cDNA Data
    4
  • Comparison Matrix
    Gene Expression + Phenotype
    • Sequences &
    Gene Models
    less
    Representative SequencesLengthStrain/SpeciesFlank
    genomic ENSMUSG00000035045 Ensembl Gene Model | MGI Sequence Detail 220960 C57BL/6J ±  kb
    transcript ENSMUST00000082183 Ensembl | MGI Sequence Detail 2831 Not Applicable  
    polypeptide ENSMUSP00000080820 Ensembl | MGI Sequence Detail 835 Not Applicable  
    For the selected sequence
    Protein
    Information
    less
    • UniProt
      4 Sequences
    • InterPro Domains
      IPR040757 Endoribonuclease Regnase 1/ZC3H12, C-terminal domain
      IPR040546 Rege-1, UBA-like domain
      IPR021869 Ribonuclease Zc3h12a-like, NYN domain
      IPR051101 ZC3H12/N4BP1 Ribonuclease and Regulator
      IPR000571 Zinc finger, CCCH-type
    Molecular
    Reagents
    less
    • All nucleic 4
      cDNA 4

      Microarray probesets 1
    Other
    Accession IDs
    less
    MGI:2685219
    References
    more
    • Summaries
      All 22
      Gene Ontology 1
      Phenotypes 7
    • Earliest
      J:80000 The FANTOM Consortium and The RIKEN Genome Exploration Research Group Phase I & II Team, Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs. Nature. 2002;420:563-573
    • Latest
      J:345621 Adams DJ, et al., Genetic determinants of micronucleus formation in vivo. Nature. 2024 Mar;627(8002):130-136
    Contributing Projects:
    Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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    Funding Information
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    Send questions and comments to User Support.     		last database update
    12/17/2024
    MGI 6.24     		The Jackson Laboratory