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Evi5l Gene Detail
Summary
  • Symbol
    Evi5l
  • Name
    ecotropic viral integration site 5 like
  • Synonyms
    1700084G18Rik, 2310039H16Rik, 3110007G05Rik, B130050I23Rik
  • Feature Type
    protein coding gene
  • IDs
    MGI:2442167
    NCBI Gene: 213027
  • Alliance
  • Transcription Start Sites
    3 TSS
Location &
Maps
more
  • Sequence Map
    Chr8:4216523-4258089 bp, + strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
  • Genetic Map
    Chromosome 8, 1.95 cM, cytoband A1.1
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    1001 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_2442167
protein coding gene Chr8:4216523-4261257 (+)
129S1/SvImJ MGP_129S1SvImJ_G0033325
protein coding gene Chr8:1146558-1196213 (+)
A/J MGP_AJ_G0033306
protein coding gene Chr8:1100364-1145898 (+)
AKR/J MGP_AKRJ_G0033237
protein coding gene Chr8:1133560-1179885 (+)
BALB/cJ MGP_BALBcJ_G0033306
protein coding gene Chr8:1153284-1199573 (+)
C3H/HeJ MGP_C3HHeJ_G0033020
protein coding gene Chr8:1145486-1190849 (+)
C57BL/6NJ MGP_C57BL6NJ_G0033818
protein coding gene Chr8:1187776-1234538 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0030790
protein coding gene Chr8:975855-1019426 (+)
CAST/EiJ MGP_CASTEiJ_G0032344
protein coding gene Chr8:1025302-1074020 (+)
CBA/J MGP_CBAJ_G0032993
protein coding gene Chr8:1223101-1267774 (+)
DBA/2J MGP_DBA2J_G0033147
protein coding gene Chr8:1061514-1106224 (+)
FVB/NJ MGP_FVBNJ_G0033094
protein coding gene Chr8:1091482-1135951 (+)
LP/J MGP_LPJ_G0033241
protein coding gene Chr8:1068475-1113110 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0033129
protein coding gene Chr8:1197075-1243315 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0033835
protein coding gene Chr8:1116473-1163153 (+)
PWK/PhJ MGP_PWKPhJ_G0032055
protein coding gene Chr8:1025520-1070686 (+)
SPRET/EiJ MGP_SPRETEiJ_G0031898
protein coding gene Chr8:1040417-1084806 (+)
WSB/EiJ MGP_WSBEiJ_G0032458
protein coding gene Chr8:1097447-1143638 (+)



Homology
more
  • Human Ortholog
    EVI5L, ecotropic viral integration site 5 like
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    EVI5L, ecotropic viral integration site 5 like
  • Links
    NCBI Gene ID: 115704
    neXtProt AC: NX_Q96CN4
    UniProt: Q96CN4

  • Chr Location
    19p13.2; chr19:7830218-7864976 (+)  GRCh38

Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    3 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic 213027 NCBI Gene Model | MGI Sequence Detail 41567 C57BL/6J ±  kb
transcript NM_001346730 RefSeq | MGI Sequence Detail 3976 C57BL/6  
polypeptide NP_001355721 RefSeq | MGI Sequence Detail 829 C57BL/6  
For the selected sequence
Protein
Information
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  • UniProt
    8 Sequences
  • InterPro Domains
    IPR000195 Rab-GAP-TBC domain
    IPR035969 Rab-GAP-TBC domain superfamily
    IPR050302 Rab GTPase-activating TBC domain-containing protein
  • GlyGen
    H3BKQ3 4 sites, 4 N-linked glycans (4 sites)
Molecular
Reagents
less
  • All nucleic 9
    cDNA 9

    Microarray probesets 5
Other
Accession IDs
less
MGI:1920322, MGI:1920785, MGI:1923700
References
more
  • Summaries
    All 26
    Developmental Gene Expression 3
    Gene Ontology 3
    Phenotypes 3
  • Earliest
    J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
  • Latest
    J:313619 Bedogni F, et al., Cell-Type-Specific Gene Expression in Developing Mouse Neocortex: Intermediate Progenitors Implicated in Axon Development. Front Mol Neurosci. 2021;14:686034

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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last database update
12/10/2024
MGI 6.24
The Jackson Laboratory