About   Help   FAQ
Specc1 Gene Detail
Summary
  • Symbol
    Specc1
  • Name
    sperm antigen with calponin homology and coiled-coil domains 1
  • Synonyms
    2810012G08Rik, B230396K10Rik, Cytsb
  • Feature Type
    protein coding gene
  • IDs
    MGI:2442356
    NCBI Gene: 432572
  • Alliance
    gene page
  • Transcription Start Sites
    16 TSS
Location &
Maps
more
  • Sequence Map
    Chr11:61847589-62113839 bp, + strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 11, 37.96 cM
  • Mapping Data
    1 experiment
Strain
Comparison
more
  • SNPs within 2kb
    7311 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_2442356
 protein coding gene Chr11:61847589-62113839 (+)
129S1/SvImJ MGP_129S1SvImJ_G0018449
 protein coding gene Chr11:61954622-62234549 (+)
A/J MGP_AJ_G0018418
 protein coding gene Chr11:59676456-59946843 (+)
AKR/J MGP_AKRJ_G0018388
 protein coding gene Chr11:61508638-61794401 (+)
BALB/cJ MGP_BALBcJ_G0018389
 protein coding gene Chr11:59962809-60232490 (+)
C3H/HeJ MGP_C3HHeJ_G0018202
 protein coding gene Chr11:61496559-61771635 (+)
C57BL/6NJ MGP_C57BL6NJ_G0018841
 protein coding gene Chr11:63917317-64202716 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0016487
 protein coding gene Chr11:56782266-57047174 (+)
CAST/EiJ MGP_CASTEiJ_G0017759
 protein coding gene Chr11:61630531-61905279 (+)
CBA/J MGP_CBAJ_G0018176
 protein coding gene Chr11:66686838-66977048 (+)
DBA/2J MGP_DBA2J_G0018285
 protein coding gene Chr11:59228881-59499930 (+)
FVB/NJ MGP_FVBNJ_G0018276
 protein coding gene Chr11:58914625-59179166 (+)
LP/J MGP_LPJ_G0018358
 protein coding gene Chr11:62514450-62791003 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0018300
 protein coding gene Chr11:67692675-67977222 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0018882
 protein coding gene Chr11:61654915-61938994 (+)
PWK/PhJ MGP_PWKPhJ_G0017532
 protein coding gene Chr11:59844884-60118760 (+)
SPRET/EiJ MGP_SPRETEiJ_G0017322
 protein coding gene Chr11:61483752-61784792 (+)
WSB/EiJ MGP_WSBEiJ_G0017811
 protein coding gene Chr11:61262990-61543701 (+)



Homology
more
  • Human Ortholog
    SPECC1, sperm antigen with calponin homology and coiled-coil domains 1
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    SPECC1, sperm antigen with calponin homology and coiled-coil domains 1
  • Synonyms
    CYTSB, HCMOGT-1, HCMOGT1, NSP, NSP5
  • Links
    NCBI Gene ID: 92521
    neXtProt AC: NX_Q5M775
    UniProt: Q5M775

  • Chr Location
    17p11.2; chr17:20008865-20319026 (+)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    9 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    17
  • GO References
    7
Molecular Function

No experimental evidence to support Molecular Function annotation, following literature review. See J:73796.
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    834
  • Tissues
    13
  • cDNA Data
    14
  • Literature Summary
    2
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic 432572 NCBI Gene Model | MGI Sequence Detail 266251 C57BL/6J ±  kb
transcript NM_001281818 RefSeq | MGI Sequence Detail 6966 C57BL/6  
polypeptide Q5SXY1 UniProt | EBI | MGI Sequence Detail 1067 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 14
    cDNA 14

    Microarray probesets 6
Other
Accession IDs
less
MGI:1923614
References
more
  • Summaries
    All 37
    Developmental Gene Expression 2
    Gene Ontology 7
    Phenotypes 9
  • Earliest
    J:137335 Roderick TH, Chromosomal inversions in studies of mammalian mutagenesis. Genetics. 1979 May;92(1 Pt 1 Suppl):s121-6
  • Latest
    J:345621 Adams DJ, et al., Genetic determinants of micronucleus formation in vivo. Nature. 2024 Mar;627(8002):130-136
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support. 		last database update
11/12/2024
MGI 6.24 		The Jackson Laboratory