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Eml5 Gene Detail
Summary
  • Symbol
    Eml5
  • Name
    echinoderm microtubule associated protein like 5
  • Synonyms
    C130068M19Rik
  • Feature Type
    protein coding gene
  • IDs
    MGI:2442513
    NCBI Gene: 319670
  • Alliance
  • Transcription Start Sites
    6 TSS
Location &
Maps
more
  • Sequence Map
    Chr12:98753064-98867743 bp, - strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
  • Genetic Map
    Chromosome 12, 49.88 cM
  • Mapping Data
    1 experiment
Strain
Comparison
more
  • SNPs within 2kb
    2720 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_2442513
protein coding gene Chr12:98752863-98867770 (-)
129S1/SvImJ MGP_129S1SvImJ_G0020009
protein coding gene Chr12:100190647-100309845 (-)
A/J MGP_AJ_G0019964
protein coding gene Chr12:96424001-96546329 (-)
AKR/J MGP_AKRJ_G0019940
protein coding gene Chr12:99028955-99151475 (-)
BALB/cJ MGP_BALBcJ_G0019950
protein coding gene Chr12:96755370-96882712 (-)
C3H/HeJ MGP_C3HHeJ_G0019752
protein coding gene Chr12:99580486-99694207 (-)
C57BL/6NJ MGP_C57BL6NJ_G0020399
protein coding gene Chr12:103237317-103370541 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0018013
protein coding gene Chr12:93391063-93510031 (-)
CAST/EiJ MGP_CASTEiJ_G0019298
protein coding gene Chr12:94631589-94755190 (-)
CBA/J MGP_CBAJ_G0019724
protein coding gene Chr12:107076694-107204104 (-)
DBA/2J MGP_DBA2J_G0019835
protein coding gene Chr12:95848250-95964583 (-)
FVB/NJ MGP_FVBNJ_G0019824
protein coding gene Chr12:94567029-94683121 (-)
LP/J MGP_LPJ_G0019911
protein coding gene Chr12:100018583-100142771 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0019866
protein coding gene Chr12:110749959-110889099 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0020428
protein coding gene Chr12:98594957-98714128 (-)
PWK/PhJ MGP_PWKPhJ_G0019062
protein coding gene Chr12:90463697-90583088 (-)
SPRET/EiJ MGP_SPRETEiJ_G0018858
protein coding gene Chr12:92757893-92878180 (-)
WSB/EiJ MGP_WSBEiJ_G0019352
protein coding gene Chr12:99426834-99545626 (-)



Homology
more
  • Human Ortholog
    EML5, EMAP like 5
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    EML5, EMAP like 5
  • Synonyms
    EMAP-2, EMAP-5, FAP16
  • Links
    NCBI Gene ID: 161436
    neXtProt AC: NX_Q05BV3
    UniProt: Q05BV3

  • Chr Location
    14q31.3; chr14:88612431-88792953 (-)  GRCh38

Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    5 phenotype references
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

No experimental evidence to support Biological Process annotation, following literature review. See J:73796.
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
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Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • cDNA Data
  • Literature Summary
Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000051166 Ensembl Gene Model | MGI Sequence Detail 114680 C57BL/6J ±  kb
transcript ENSMUST00000223282 Ensembl | MGI Sequence Detail 7595 Not Applicable  
polypeptide ENSMUSP00000152709 Ensembl | MGI Sequence Detail 1977 Not Applicable  
For the selected sequence
Protein
Information
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  • UniProt
    6 Sequences
  • Protein Ontology
    PR:000007060 echinoderm microtubule-associated protein-like 5
  • InterPro Domains
    IPR024977 Anaphase-promoting complex subunit 4-like, WD40 domain
    IPR005108 HELP motif
    IPR011047 Quinoprotein alcohol dehydrogenase-like superfamily
    IPR001680 WD40 repeat
    IPR019775 WD40 repeat, conserved site
    IPR036322 WD40-repeat-containing domain superfamily
    IPR015943 WD40/YVTN repeat-like-containing domain superfamily
    IPR050630 WD repeat Echinoderm Microtubule-associated Protein-like
Molecular
Reagents
less
  • All nucleic 11
    cDNA 11

    Microarray probesets 9
Other
Accession IDs
less
MGI:2446158
References
more
  • Summaries
    All 26
    Developmental Gene Expression 1
    Gene Ontology 2
    Phenotypes 5
  • Earliest
    J:80000 The FANTOM Consortium and The RIKEN Genome Exploration Research Group Phase I & II Team, Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs. Nature. 2002;420:563-573
  • Latest
    J:156036 Schilling K, et al., The treasury of the commons: making use of public gene expression resources to better characterize the molecular diversity of inhibitory interneurons in the cerebellar cortex. Cerebellum. 2009 Dec;8(4):477-89

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Funding Information
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last database update
11/12/2024
MGI 6.24
The Jackson Laboratory