Atp10b MGI Mouse Gene Detail - MGI:2442688

Symbol

Atp10b
Name

ATPase, class V, type 10B
Synonyms

5930426O13Rik, 9030605H24Rik

Feature Type

protein coding gene
IDs

MGI:2442688
NCBI Gene: 319767
Alliance

gene page
Transcription Start Sites

3 TSS

Sequence Map

Chr11:43040704-43153112 bp, + strand
From Ensembl annotation of GRCm39
View this region in JBrowse
Genome Browsers

Ensembl | UCSC | NCBI

Genetic Map

Chromosome 11, 25.68 cM
Mapping Data

1 experiment

SNPs within 2kb

3240 from dbSNP Build 142
Strain Annotations

18

For selected strains:

Strain	Gene Model ID	Feature Type	Coordinates
C57BL/6J	MGI_C57BL6J_2442688	protein coding gene	Chr11:42902991-43153112 (+)
129S1/SvImJ	MGP_129S1SvImJ_G0018170	protein coding gene	Chr11:41897041-42009244 (+)
A/J	MGP_AJ_G0018142	protein coding gene	Chr11:40297673-40409627 (+)
AKR/J	MGP_AKRJ_G0018106	protein coding gene	Chr11:41482297-41595766 (+)
BALB/cJ	MGP_BALBcJ_G0018111	protein coding gene	Chr11:40473600-40584997 (+)
C3H/HeJ	MGP_C3HHeJ_G0017924	protein coding gene	Chr11:41518506-41631545 (+)
C57BL/6NJ	MGP_C57BL6NJ_G0018565	protein coding gene	Chr11:43187227-43302378 (+)
CAROLI/EiJ	MGP_CAROLIEiJ_G0016220	protein coding gene	Chr11:38384284-38496587 (+)
CAST/EiJ	MGP_CASTEiJ_G0017488	protein coding gene	Chr11:41567127-41705061 (+)
CBA/J	MGP_CBAJ_G0017897	protein coding gene	Chr11:45173512-45294185 (+)
DBA/2J	MGP_DBA2J_G0018007	protein coding gene	Chr11:40097591-40209144 (+)
FVB/NJ	MGP_FVBNJ_G0018001	protein coding gene	Chr11:39785831-39898979 (+)
LP/J	MGP_LPJ_G0018079	protein coding gene	Chr11:42152626-42265897 (+)
NOD/ShiLtJ	MGP_NODShiLtJ_G0018025	protein coding gene	Chr11:46818603-46947532 (+)
NZO/HlLtJ	MGP_NZOHlLtJ_G0018604	protein coding gene	Chr11:41628650-41744026 (+)
PWK/PhJ	MGP_PWKPhJ_G0017269	protein coding gene	Chr11:40111973-40255975 (+)
SPRET/EiJ	MGP_SPRETEiJ_G0017061	protein coding gene	Chr11:41424194-41558785 (+)
WSB/EiJ	MGP_WSBEiJ_G0017537	protein coding gene	Chr11:41268654-41381976 (+)

Human Ortholog

ATP10B, ATPase phospholipid transporting 10B (putative)

Vertebrate Orthologs

3

Vertebrate Orthology Source

Alliance of Genome Resources

Human Ortholog

ATP10B, ATPase phospholipid transporting 10B (putative)
Synonyms

ATPVB
Links

HGNC:13543

NCBI Gene ID: 23120

neXtProt AC: NX_O94823

UniProt: O94823
Chr Location

5q34; chr5:160563120-160929360 (-) GRCh38

MGI Vertebrate Homology

Atp10b stringent orthology
1 human;1 mouse;1 rat;1 zebrafish
HCOP

vertebrate homology predictions: ATP10B
Gene Tree

Atp10b

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Phenotype Summary

7 phenotype references

All Mutations and Alleles

5
Chemically induced (other)

1
Endonuclease-mediated

1
Radiation induced

1
Targeted

2
Genomic Mutations

2 involving Atp10b
Incidental Mutations

Mutagenetix , APF , CvDC
Find Mice (IMSR)

75 strains or lines available

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All GO Annotations

24
GO References

8

Molecular Function

carbohydrate derivative binding	cytoskeletal protein binding	DNA binding	enzyme regulator	hydrolase	ligase	lipid binding	oxidoreductase	RNA binding	signaling receptor activity	signaling receptor binding	transcription	transferase	transporter

Biological Process

carbohydrate derivative metabolism	cell differentiation	cell population proliferation	cellular component organization	DNA-templated transcription	establishment of localization	homeostatic process	immune system process	lipid metabolic process	programmed cell death	protein metabolic process	response to stimulus	signaling	system development

Cellular Component

cell projection	cytoplasmic vesicle	cytoskeleton	cytosol	endoplasmic reticulum	endosome	extracellular region	Golgi apparatus	mitochondrion	membraneless organelle	nucleus	organelle envelope	organelle lumen	plasma membrane	protein-containing complex	synapse	vacuole

Click cells to view annotations.

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Expression Overview

GXD's primary emphasis is on endogenous gene expression during development. Click on grid cells to view annotations.

Blue cells = expressed in wild-type.
Gray triangles = other expression annotations only
(e.g. absence of expression or data from mutants).

early conceptus	embryo ectoderm	embryo endoderm	embryo mesoderm	embryo mesenchyme	extraembryonic component	alimentary system	auditory system	branchial arches	cardiovascular system	connective tissue	endocrine system	exocrine system	hemolymphoid system	integumental system	limbs	liver and biliary system	musculoskeletal system	nervous system	olfactory system	reproductive system	respiratory system	urinary system	visual system

Click cells to view annotations.

Assay Results

706
cDNA Data

13

Tissue x Stage Matrix

Other Mouse Links

Allen Institute

GEO

Expression Atlas
Other Vertebrate Links

Xenbase atp10b

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All Sequences

44
RefSeq

8
UniProt

4
CCDS

CCDS36129.1

Ensembl

ENSMUSG00000055415 (Evidence)
NCBI Gene

319767

			Length	Strain/Species	Flank
genomic	ENSMUSG00000055415	Ensembl Gene Model \| MGI Sequence Detail	112409	C57BL/6J	± kb
transcript	ENSMUST00000077659	Ensembl \| MGI Sequence Detail	6825	Not Applicable
polypeptide	ENSMUSP00000076844	Ensembl \| MGI Sequence Detail	1474	Not Applicable

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UniProt

4 Sequences
Protein Ontology

PR:000031184 phospholipid-transporting ATPase VB

(term hierarchy)
EC

7.6.2.1
InterPro Domains

IPR036412 HAD-like superfamily

IPR023214 HAD superfamily

IPR001757 P-type ATPase

IPR008250 P-type ATPase, A domain superfamily

IPR032630 P-type ATPase, C-terminal

IPR023299 P-type ATPase, cytoplasmic domain N

IPR044492 P-type ATPase, haloacid dehalogenase domain

IPR032631 P-type ATPase, N-terminal

IPR018303 P-type ATPase, phosphorylation site

IPR006539 P-type ATPase, subfamily IV

IPR023298 P-type ATPase, transmembrane domain superfamily

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All nucleic 13

cDNA 13

Microarray probesets 3

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MGI:1924357

Summaries

All 33

Gene Ontology 8

Phenotypes 7
Earliest

J:137335 Roderick TH, Chromosomal inversions in studies of mammalian mutagenesis. Genetics. 1979 May;92(1 Pt 1 Suppl):s121-6
Latest

J:326541 Cyagen Biosciences Inc., Cyagen Biosciences Website. 2022;

TSS for Atp10b:

(View these features in JBrowse)

Transcription Start Site	Location	Distance from Gene 5'-end
Tssr100989	Chr11:43046475-43046531 (+)	5,799 bp
Tssr100990	Chr11:43046533-43046545 (+)	5,835 bp
Tssr100991	Chr11:43046608-43046611 (+)	5,906 bp

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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