About   Help   FAQ
Thoc2l Gene Detail
Summary
  • Symbol
    Thoc2l
  • Name
    THO complex subunit 2-like
  • Synonyms
    BC005561, Gm3179
  • Feature Type
    protein coding gene
  • IDs
    MGI:3040669
    NCBI Gene: 100042165
  • Alliance
    gene page
  • Transcription Start Sites
    3 TSS
Location &
Maps
more
  • Sequence Map
    Chr5:104656216-104702073 bp, + strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 5, 50.68 cM
  • Mapping Data
    4 experiments
Strain
Comparison
more
  • SNPs within 2kb
    603 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_3040669
 protein coding gene Chr5:104656172-104702073 (+)
129S1/SvImJ MGP_129S1SvImJ_G0006728
 lincRNA gene Chr5:106205600-106235781 (+)
A/J MGP_AJ_G0006722
 lincRNA gene Chr5:102224200-102255592 (+)
AKR/J MGP_AKRJ_G0006692
 lincRNA gene Chr5:105532264-105562014 (+)
BALB/cJ MGP_BALBcJ_G0006697
 lincRNA gene Chr5:103284183-103316248 (+)
C3H/HeJ MGP_C3HHeJ_G0006643
 lincRNA gene Chr5:105927672-105961876 (+)
C57BL/6NJ MGP_C57BL6NJ_G0006862
 lincRNA gene Chr5:110561490-110591591 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0006119
 lincRNA gene Chr5:97329588-97345010 (+)
CAST/EiJ MGP_CASTEiJ_G0006566
 lincRNA gene Chr5:104642331-104672800 (+)
CBA/J MGP_CBAJ_G0006624
 lincRNA gene Chr5:114404178-114441834 (+)
DBA/2J MGP_DBA2J_G0006645
 lincRNA gene Chr5:102434885-102450418 (+)
FVB/NJ MGP_FVBNJ_G0006669
 lincRNA gene Chr5:101194973-101224716 (+)
LP/J MGP_LPJ_G0006729
 lincRNA gene Chr5:106809764-106840552 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0006653
 lincRNA gene Chr5:119311608-119345487 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0006864
 lincRNA gene Chr5:105045973-105074620 (+)
PWK/PhJ MGP_PWKPhJ_G0006505
 lincRNA gene Chr5:100864711-100893757 (+)
SPRET/EiJ MGP_SPRETEiJ_G0006411
 lincRNA gene Chr5:102707139-102743249 (+)
WSB/EiJ MGP_WSBEiJ_G0006617
 lincRNA gene Chr5:105437881-105469183 (+)



Homology
more
  • Human Ortholog
    THOC2, THO complex subunit 2
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    THOC2, THO complex subunit 2
  • Synonyms
    AMC7, CXorf3, dJ506G2.1, hTREX120, MRX12, MRX35, THO2, XLID12
  • Links
    NCBI Gene ID: 57187
    neXtProt AC: NX_Q8NI27
    UniProt: Q8NI27

  • Chr Location
    Xq25; chrX:123600561-123733056 (-)  GRCh38
Human Diseases
more
  • Diseases
    1 with human THOC2 associations

Human Disease Mouse Models
      
IDs
 View 1 model
Click on a disease name to see all genes associated with that disease.

Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    9 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    11
  • GO References
    2
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    751
  • Tissues
    31
  • cDNA Data
    66
  • Literature Summary
    2
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000097392 Ensembl Gene Model | MGI Sequence Detail 45858 C57BL/6J ±  kb
transcript ENSMUST00000239307 Ensembl | MGI Sequence Detail 9550 Not Applicable  
polypeptide ENSMUSP00000159241 Ensembl | MGI Sequence Detail 1589 Not Applicable  
For the selected sequence
Protein
Information
less
  • UniProt
    4 Sequences
  • InterPro Domains
    IPR040007 THO complex subunit 2
    IPR032302 THO complex subunit 2, N-terminal domain
    IPR021418 THO complex, subunitTHOC2, C-terminal
    IPR021726 THO complex, subunitTHOC2, N-terminal
Molecular
Reagents
less
  • All nucleic 66
    cDNA 66

    Microarray probesets 4
Other
Accession IDs
less
MGI:2140897, MGI:2442700, MGI:3781358, MGI:6316324
References
more
  • Summaries
    All 33
    Developmental Gene Expression 2
    Gene Ontology 2
    Phenotypes 9
  • Earliest
    J:134667 Roderick TH, et al., Two radiation-induced chromosomal inversions in mice (Mus musculus). Proc Natl Acad Sci U S A. 1970 Oct;67(2):961-7
  • Latest
    J:153498 Diez-Roux G, et al., A high-resolution anatomical atlas of the transcriptome in the mouse embryo. PLoS Biol. 2011;9(1):e1000582
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support. 		last database update
11/05/2024
MGI 6.24 		The Jackson Laboratory