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Cadm2 Gene Detail
Summary
  • Symbol
    Cadm2
  • Name
    cell adhesion molecule 2
  • Synonyms
    2900078E11Rik, A830029E02Rik, Igsf4d, Necl3, SynCAM2
  • Feature Type
    protein coding gene
  • IDs
    MGI:2442722
    NCBI Gene: 239857
  • Alliance
    gene page
  • Transcription Start Sites
    23 TSS
Location &
Maps
more
  • Sequence Map
    Chr16:66452307-67417796 bp, - strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 16, 37.96 cM
  • Mapping Data
    1 experiment
Strain
Comparison
more
  • SNPs within 2kb
    29406 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_2442722
 protein coding gene Chr16:66452302-67417825 (-)
129S1/SvImJ MGP_129S1SvImJ_G0022947
 protein coding gene Chr16:66232930-67281478 (-)
A/J MGP_AJ_G0022915
 protein coding gene Chr16:63372620-64351974 (-)
AKR/J MGP_AKRJ_G0022885
 protein coding gene Chr16:65376530-66359344 (-)
BALB/cJ MGP_BALBcJ_G0022917
 protein coding gene Chr16:63595803-64591288 (-)
C3H/HeJ MGP_C3HHeJ_G0022679
 protein coding gene Chr16:65667652-66699897 (-)
C57BL/6NJ MGP_C57BL6NJ_G0023365
 protein coding gene Chr16:68197858-69277064 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0020868
 protein coding gene Chr16:62322810-63255346 (-)
CAST/EiJ MGP_CASTEiJ_G0022202
 protein coding gene Chr16:65884893-66965508 (-)
CBA/J MGP_CBAJ_G0022650
 protein coding gene Chr16:71113030-72208772 (-)
DBA/2J MGP_DBA2J_G0022782
 protein coding gene Chr16:63160072-64133885 (-)
FVB/NJ MGP_FVBNJ_G0022756
 protein coding gene Chr16:62729177-63697416 (-)
LP/J MGP_LPJ_G0022851
 protein coding gene Chr16:66045082-67110008 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0022775
 protein coding gene Chr16:72455901-73833488 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0023381
 protein coding gene Chr16:65465845-66497867 (-)
PWK/PhJ MGP_PWKPhJ_G0021945
 protein coding gene Chr16:63313605-64309474 (-)
SPRET/EiJ MGP_SPRETEiJ_G0021774
 protein coding gene Chr16:65138996-66163712 (-)
WSB/EiJ MGP_WSBEiJ_G0022249
 protein coding gene Chr16:65518809-66584840 (-)



Homology
more
  • Human Ortholog
    CADM2, cell adhesion molecule 2
  • Vertebrate Orthologs
    4
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    CADM2, cell adhesion molecule 2
  • Synonyms
    IGSF4D, Necl-3, NECL3, synCAM2, SynCAM 2, SynCAM-2
  • Links
    NCBI Gene ID: 253559
    neXtProt AC: NX_Q8N3J6
    UniProt: Q8N3J6

  • Chr Location
    3p12.1; chr3:84958989-86074429 (+)  GRCh38
Human Diseases
more
  • Diseases
    5 with human CADM2 associations

Human Disease Mouse Models
      
IDs
IDs
IDs
IDs
IDs
Click on a disease name to see all genes associated with that disease.

Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    1 phenotype from 1 allele in 1 genetic background
    14 phenotype references
Mice with ubiquitous conditional deletion of the gene do not display any neurological abnormalities.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    9
  • GO References
    5
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    836
  • Tissues
    20
  • cDNA Data
    14
  • Literature Summary
    6
Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000064115 Ensembl Gene Model | MGI Sequence Detail 965490 C57BL/6J ±  kb
transcript ENSMUST00000128168 Ensembl | MGI Sequence Detail 1308 Not Applicable  
polypeptide ENSMUSP00000134554 Ensembl | MGI Sequence Detail 435 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 15
    cDNA 14
    Other 1

    Microarray probesets 7
Other
Accession IDs
less
MGI:1920236
References
more
  • Summaries
    All 44
    Developmental Gene Expression 6
    Gene Ontology 5
    Phenotypes 14
  • Earliest
    J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
  • Latest
    J:337782 Sanchez-Roige S, et al., CADM2 is implicated in impulsive personality and numerous other traits by genome- and phenome-wide association studies in humans and mice. Transl Psychiatry. 2023 May 12;13(1):167
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
12/10/2024
MGI 6.24 		The Jackson Laboratory