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Krt222 Gene Detail
Summary
  • Symbol
    Krt222
  • Name
    keratin 222
  • Synonyms
    6330509G02Rik
  • Feature Type
    protein coding gene
  • IDs
    MGI:2442728
    NCBI Gene: 268481
  • Alliance
    gene page
  • Transcription Start Sites
    1 TSS
Location &
Maps
more
  • Sequence Map
    Chr11:99123587-99134911 bp, - strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 11, 62.92 cM
  • Mapping Data
    1 experiment
Strain
Comparison
more
  • SNPs within 2kb
    415 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_2442728
 protein coding gene Chr11:99123587-99134973 (-)
129S1/SvImJ MGP_129S1SvImJ_G0019085
 protein coding gene Chr11:101882232-101893556 (-)
A/J MGP_AJ_G0019053
 protein coding gene Chr11:97597490-97608802 (-)
AKR/J MGP_AKRJ_G0019023
 protein coding gene Chr11:100620779-100632096 (-)
BALB/cJ MGP_BALBcJ_G0019027
 protein coding gene Chr11:98092635-98104013 (-)
C3H/HeJ MGP_C3HHeJ_G0018840
 protein coding gene Chr11:100773964-100785287 (-)
C57BL/6NJ MGP_C57BL6NJ_G0019478
 protein coding gene Chr11:105016237-105027560 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0017110
 protein coding gene Chr11:95156234-95168687 (-)
CAST/EiJ MGP_CASTEiJ_G0018395
 protein coding gene Chr11:101763296-101775406 (-)
CBA/J MGP_CBAJ_G0018811
 protein coding gene Chr11:109373608-109384992 (-)
DBA/2J MGP_DBA2J_G0018919
 protein coding gene Chr11:97159029-97170347 (-)
FVB/NJ MGP_FVBNJ_G0018908
 protein coding gene Chr11:96675369-96686680 (-)
LP/J MGP_LPJ_G0018989
 protein coding gene Chr11:102353453-102364766 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0018935
 protein coding gene Chr11:109071122-109084313 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0019518
 protein coding gene Chr11:100983423-100994851 (-)
PWK/PhJ MGP_PWKPhJ_G0018166
 protein coding gene Chr11:98232439-98244078 (-)
SPRET/EiJ MGP_SPRETEiJ_G0017954
 protein coding gene Chr11:100734513-100747660 (-)
WSB/EiJ MGP_WSBEiJ_G0018443
 protein coding gene Chr11:100953544-100964854 (-)



Homology
more
  • Human Ortholog
    KRT222, keratin 222
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    KRT222, keratin 222
  • Synonyms
    KA21, KRT222P
  • Links
    NCBI Gene ID: 125113
    neXtProt AC: NX_Q8N1A0
    UniProt: Q8N1A0

  • Chr Location
    17q21.2; chr17:40654665-40665181 (-)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    8 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    2
  • GO References
    2
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

No experimental evidence to support Biological Process annotation, following literature review. See J:73796.
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    706
  • cDNA Data
    9
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000035849 Ensembl Gene Model | MGI Sequence Detail 11325 C57BL/6J ±  kb
transcript ENSMUST00000103132 Ensembl | MGI Sequence Detail 3072 Not Applicable  
polypeptide ENSMUSP00000099421 Ensembl | MGI Sequence Detail 294 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 9
    cDNA 9

    Microarray probesets 5
References
more
  • Summaries
    All 29
    Gene Ontology 2
    Phenotypes 8
  • Earliest
    J:56548 Zheng B, et al., Engineering a mouse balancer chromosome. Nat Genet. 1999 Aug;22(4):375-8
  • Latest
    J:230728 Kumar V, et al., A keratin scaffold regulates epidermal barrier formation, mitochondrial lipid composition, and activity. J Cell Biol. 2015 Dec 7;211(5):1057-75
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
11/12/2024
MGI 6.24 		The Jackson Laboratory