Cdh7 MGI Mouse Gene Detail - MGI:2442792

Symbol

Cdh7
Name

cadherin 7, type 2
Synonyms

9330156F07Rik, CDH7L1

Feature Type

protein coding gene
IDs

MGI:2442792
NCBI Gene: 241201
Alliance

gene page
Transcription Start Sites

2 TSS

Sequence Map

Chr1:109910161-110067887 bp, + strand
From Ensembl annotation of GRCm39
View this region in JBrowse
Genome Browsers

Ensembl | UCSC | NCBI

Genetic Map

Chromosome 1, 50.73 cM
Mapping Data

2 experiments

SNPs within 2kb

5283 from dbSNP Build 142
Strain Annotations

18

For selected strains:

Strain	Gene Model ID	Feature Type	Coordinates
C57BL/6J	MGI_C57BL6J_2442792	protein coding gene	Chr1:109909967-110073002 (+)
129S1/SvImJ	MGP_129S1SvImJ_G0016385	protein coding gene	Chr1:112253381-112433704 (+)
A/J	MGP_AJ_G0016365	protein coding gene	Chr1:108285908-108446916 (+)
AKR/J	MGP_AKRJ_G0016329	protein coding gene	Chr1:111361213-111525204 (+)
BALB/cJ	MGP_BALBcJ_G0016325	protein coding gene	Chr1:108438799-108601929 (+)
C3H/HeJ	MGP_C3HHeJ_G0016152	protein coding gene	Chr1:111757677-111922517 (+)
C57BL/6NJ	MGP_C57BL6NJ_G0016784	protein coding gene	Chr1:116558800-116750280 (+)
CAROLI/EiJ	MGP_CAROLIEiJ_G0014502	protein coding gene	Chr1:102287752-102443957 (+)
CAST/EiJ	MGP_CASTEiJ_G0015735	protein coding gene	Chr1:110841108-111007645 (+)
CBA/J	MGP_CBAJ_G0016124	protein coding gene	Chr1:120551365-120726188 (+)
DBA/2J	MGP_DBA2J_G0016231	protein coding gene	Chr1:107413196-107570673 (+)
FVB/NJ	MGP_FVBNJ_G0016230	protein coding gene	Chr1:106279844-106439379 (+)
LP/J	MGP_LPJ_G0016304	protein coding gene	Chr1:113544780-113720385 (+)
NOD/ShiLtJ	MGP_NODShiLtJ_G0016257	protein coding gene	Chr1:125590584-125812626 (+)
NZO/HlLtJ	MGP_NZOHlLtJ_G0016822	protein coding gene	Chr1:111331685-111501494 (+)
PWK/PhJ	MGP_PWKPhJ_G0015520	protein coding gene	Chr1:106419393-106584824 (+)
SPRET/EiJ	MGP_SPRETEiJ_G0015308	protein coding gene	Chr1:109991830-110168790 (+)
WSB/EiJ	MGP_WSBEiJ_G0015797	protein coding gene	Chr1:111176727-111345845 (+)

Human Ortholog

CDH7, cadherin 7

Vertebrate Orthologs

3

Vertebrate Orthology Source

Alliance of Genome Resources

Human Ortholog

CDH7, cadherin 7
Synonyms

CDH7L1
Links

HGNC:1766

NCBI Gene ID: 1005

neXtProt AC: NX_Q9ULB5

UniProt: Q9ULB5
Chr Location

18q22.1; chr18:65750252-65890337 (+) GRCh38

MGI Vertebrate Homology

Cdh7 stringent orthology
1 human;1 mouse;1 rat;1 zebrafish
HCOP

vertebrate homology predictions: CDH7
Gene Tree

Cdh7

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Phenotype Summary

1 phenotype from 1 allele in 1 genetic background
9 phenotype references

Phenotype Overview

Blue squares indicate phenotypes directly attributed to mutations/alleles of this gene.

adipose tissue	behavior/neurological	cardiovascular system	cellular	craniofacial	digestive/alimentary system	embryo	endocrine/exocrine glands	growth/size/body	hearing/vestibular/ear	hematopoietic system	homeostasis/metabolism	integument	immune system	limbs/digits/tail	liver/biliary system	mortality/aging	muscle	nervous system	pigmentation	renal/urinary system	reproductive system	respiratory system	skeleton	taste/olfaction	neoplasm	vision/eye

Click cells to view annotations.

All Mutations and Alleles

5
Chemically induced (other)

2
Endonuclease-mediated

1
Radiation induced

1
Targeted

1
Genomic Mutations

3 involving Cdh7
Incidental Mutations

Mutagenetix , APF
Find Mice (IMSR)

63 strains or lines available
Comparison Matrix

Gene Expression + Phenotype

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All GO Annotations

13
GO References

3

Molecular Function

carbohydrate derivative binding	cytoskeletal protein binding	DNA binding	enzyme regulator	hydrolase	ligase	lipid binding	oxidoreductase	RNA binding	signaling receptor activity	signaling receptor binding	transcription	transferase	transporter

Biological Process

carbohydrate derivative metabolism	cell differentiation	cell population proliferation	cellular component organization	DNA-templated transcription	establishment of localization	homeostatic process	immune system process	lipid metabolic process	programmed cell death	protein metabolic process	response to stimulus	signaling	system development

Cellular Component

cell projection	cytoplasmic vesicle	cytoskeleton	cytosol	endoplasmic reticulum	endosome	extracellular region	Golgi apparatus	mitochondrion	membraneless organelle	nucleus	organelle envelope	organelle lumen	plasma membrane	protein-containing complex	synapse	vacuole

Click cells to view annotations.

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Expression Overview

GXD's primary emphasis is on endogenous gene expression during development. Click on grid cells to view annotations.

Blue cells = expressed in wild-type.
Gray triangles = other expression annotations only
(e.g. absence of expression or data from mutants).

early conceptus	embryo ectoderm	embryo endoderm	embryo mesoderm	embryo mesenchyme	extraembryonic component	alimentary system	auditory system	branchial arches	cardiovascular system	connective tissue	endocrine system	exocrine system	hemolymphoid system	integumental system	limbs	liver and biliary system	musculoskeletal system	nervous system	olfactory system	reproductive system	respiratory system	urinary system	visual system

Click cells to view annotations.

Assay Results

825
Tissues

66
cDNA Data

12
Literature Summary

16

Images

Tissue x Stage Matrix

Comparison Matrix

Gene Expression + Phenotype

Other Mouse Links

Allen Institute

GEO

Expression Atlas
Other Vertebrate Links

GEISHA CDH7

ZFIN cdh7a

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All Sequences

97
RefSeq

38
UniProt

7
CCDS

CCDS15221.1

Ensembl

ENSMUSG00000026312 (Evidence)
NCBI Gene

241201

			Length	Strain/Species	Flank
genomic	ENSMUSG00000026312	Ensembl Gene Model \| MGI Sequence Detail	157727	C57BL/6J	± kb
transcript	ENSMUST00000172005	Ensembl \| MGI Sequence Detail	3353	Not Applicable
polypeptide	ENSMUSP00000129715	Ensembl \| MGI Sequence Detail	785	Not Applicable

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UniProt

7 Sequences
Protein Ontology

PR:000005248 cadherin-7

(term hierarchy)
PDB

6CGS
InterPro Domains

IPR039808 Cadherin

IPR020894 Cadherin conserved site

IPR002126 Cadherin-like

IPR015919 Cadherin-like superfamily

IPR000233 Cadherin, Y-type LIR-motif

IPR027397 Catenin binding domain superfamily
GlyGen

Q8BM92 2 sites, 2 N-linked glycans (2 sites)

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All nucleic 16

cDNA 12

Primer pair 3

Other 1

Microarray probesets 3

Summaries

All 46

Developmental Gene Expression 16

Gene Ontology 3

Phenotypes 9
Earliest

J:134667 Roderick TH, et al., Two radiation-induced chromosomal inversions in mice (Mus musculus). Proc Natl Acad Sci U S A. 1970 Oct;67(2):961-7
Latest

J:345621 Adams DJ, et al., Genetic determinants of micronucleus formation in vivo. Nature. 2024 Mar;627(8002):130-136

TSS for Cdh7:

(View these features in JBrowse)

Transcription Start Site	Location	Distance from Gene 5'-end
Tssr8348	Chr1:109911007-109911033 (+)	859 bp
Tssr175	Chr1:109911481-109911492 (+)	1,326 bp

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources Funding Information Warranty Disclaimer, Privacy Notice, Licensing, & Copyright Send questions and comments to User Support.	last database update 11/12/2024 MGI 6.24