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Lrrc38 Gene Detail
Summary
  • Symbol
    Lrrc38
  • Name
    leucine rich repeat containing 38
  • Synonyms
    A230053A07Rik
  • Feature Type
    protein coding gene
  • IDs
    MGI:2442845
    NCBI Gene: 242735
  • Alliance
    gene page
  • Transcription Start Sites
    2 TSS
Location &
Maps
more
  • Sequence Map
    Chr4:143076327-143097602 bp, + strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 4, 77.55 cM
  • Mapping Data
    1 experiment
Strain
Comparison
more
  • SNPs within 2kb
    286 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_2442845
 protein coding gene Chr4:143076242-143097602 (+)
129S1/SvImJ MGP_129S1SvImJ_G0029067
 protein coding gene Chr4:146571269-146593967 (+)
A/J MGP_AJ_G0029027
 protein coding gene Chr4:140186052-140207841 (+)
AKR/J MGP_AKRJ_G0028979
 protein coding gene Chr4:144218216-144240000 (+)
BALB/cJ MGP_BALBcJ_G0029051
 protein coding gene Chr4:140853719-140875249 (+)
C3H/HeJ MGP_C3HHeJ_G0028765
 protein coding gene Chr4:144606571-144628885 (+)
C57BL/6NJ MGP_C57BL6NJ_G0029492
 protein coding gene Chr4:151599778-151622024 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0026762
 protein coding gene Chr4:133032996-133053378 (+)
CAST/EiJ MGP_CASTEiJ_G0028197
 protein coding gene Chr4:142905676-142930531 (+)
CBA/J MGP_CBAJ_G0028729
 protein coding gene Chr4:156151014-156174928 (+)
DBA/2J MGP_DBA2J_G0028879
 protein coding gene Chr4:140531638-140553060 (+)
FVB/NJ MGP_FVBNJ_G0028846
 protein coding gene Chr4:139698063-139718945 (+)
LP/J MGP_LPJ_G0028978
 protein coding gene Chr4:146603566-146627833 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0028872
 protein coding gene Chr4:159805829-159832135 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0029530
 protein coding gene Chr4:144773019-144795609 (+)
PWK/PhJ MGP_PWKPhJ_G0027919
 protein coding gene Chr4:137446028-137467546 (+)
SPRET/EiJ MGP_SPRETEiJ_G0027742
 protein coding gene Chr4:140595614-140622676 (+)
WSB/EiJ MGP_WSBEiJ_G0028275
 protein coding gene Chr4:145074040-145097524 (+)



Homology
more
  • Human Ortholog
    LRRC38, leucine rich repeat containing 38
  • Vertebrate Orthologs
    4
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    LRRC38, leucine rich repeat containing 38
  • Links
    NCBI Gene ID: 126755
    neXtProt AC: NX_Q5VT99
    UniProt: Q5VT99

  • Chr Location
    1p36.21; chr1:13474973-13514003 (-)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    3 phenotypes from 1 allele in 1 genetic background
    5 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
    13
  • GO References
    3
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    706
  • cDNA Data
    8
  • Comparison Matrix
    Gene Expression + Phenotype
    • Sequences &
    Gene Models
    less
    Representative SequencesLengthStrain/SpeciesFlank
    genomic ENSMUSG00000028584 Ensembl Gene Model | MGI Sequence Detail 21276 C57BL/6J ±  kb
    transcript ENSMUST00000052458 Ensembl | MGI Sequence Detail 2324 Not Applicable  
    polypeptide ENSMUSP00000053597 Ensembl | MGI Sequence Detail 298 Not Applicable  
    For the selected sequence
    Protein
    Information
    less
    • UniProt
      1 Sequence
    • Protein Ontology
      PR:000030507 leucine-rich repeat-containing protein 38
      (term hierarchy)
    • InterPro Domains
      IPR000483 Cysteine-rich flanking region, C-terminal
      IPR001611 Leucine-rich repeat
      IPR032675 Leucine-rich repeat domain superfamily
      IPR000372 Leucine-rich repeat N-terminal domain
      IPR003591 Leucine-rich repeat, typical subtype
      IPR051432 Voltage and calcium-activated potassium channel auxiliary protein
    • GlyGen
      A2VDH3 1 site
    Molecular
    Reagents
    less
    • All nucleic 8
      cDNA 8

      Microarray probesets 2
    References
    more
    • Summaries
      All 24
      Gene Ontology 3
      Phenotypes 5
    • Earliest
      J:80000 The FANTOM Consortium and The RIKEN Genome Exploration Research Group Phase I & II Team, Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs. Nature. 2002;420:563-573
    • Latest
      J:153498 Diez-Roux G, et al., A high-resolution anatomical atlas of the transcriptome in the mouse embryo. PLoS Biol. 2011;9(1):e1000582
    Contributing Projects:
    Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
    Citing These Resources
    Funding Information
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    Send questions and comments to User Support.     		last database update
    11/12/2024
    MGI 6.24     		The Jackson Laboratory