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Eml6 Gene Detail
Summary
  • Symbol
    Eml6
  • Name
    echinoderm microtubule associated protein like 6
  • Synonyms
    2900083P10Rik, C230094A16Rik
  • Feature Type
    protein coding gene
  • IDs
    MGI:2442895
    NCBI Gene: 237711
  • Alliance
    gene page
  • Transcription Start Sites
    3 TSS
Location &
Maps
more
  • Sequence Map
    Chr11:29693048-29976033 bp, - strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 11, 16.83 cM
  • Mapping Data
    1 experiment
Strain
Comparison
more
  • SNPs within 2kb
    7684 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_2442895
 protein coding gene Chr11:29693044-29976044 (-)
129S1/SvImJ MGP_129S1SvImJ_G0018112
 protein coding gene Chr11:27773909-28067795 (-)
A/J MGP_AJ_G0018084
 protein coding gene Chr11:26733422-27018367 (-)
AKR/J MGP_AKRJ_G0018049
 protein coding gene Chr11:27608997-27903019 (-)
BALB/cJ MGP_BALBcJ_G0018052
 protein coding gene Chr11:26941399-27232556 (-)
C3H/HeJ MGP_C3HHeJ_G0017866
 protein coding gene Chr11:27522927-27813463 (-)
C57BL/6NJ MGP_C57BL6NJ_G0018505
 protein coding gene Chr11:28712724-29020663 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0016162
 protein coding gene Chr11:25365509-25639437 (-)
CAST/EiJ MGP_CASTEiJ_G0017428
 protein coding gene Chr11:27586384-27884772 (-)
CBA/J MGP_CBAJ_G0017840
 protein coding gene Chr11:30050794-30374679 (-)
DBA/2J MGP_DBA2J_G0017950
 protein coding gene Chr11:26591502-26873714 (-)
FVB/NJ MGP_FVBNJ_G0017942
 protein coding gene Chr11:26399321-26682305 (-)
LP/J MGP_LPJ_G0018022
 protein coding gene Chr11:28016777-28327771 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0017968
 protein coding gene Chr11:31180241-31484350 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0018545
 protein coding gene Chr11:27719848-28019735 (-)
PWK/PhJ MGP_PWKPhJ_G0017210
 protein coding gene Chr11:26683101-26965151 (-)
SPRET/EiJ MGP_SPRETEiJ_G0017005
 protein coding gene Chr11:27416695-27716502 (-)
WSB/EiJ MGP_WSBEiJ_G0017481
 protein coding gene Chr11:27413865-27702006 (-)



Homology
more
  • Human Ortholog
    EML6, EMAP like 6
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    EML6, EMAP like 6
  • Links
    NCBI Gene ID: 400954
    neXtProt AC: NX_Q6ZMW3
    UniProt: Q6ZMW3

  • Chr Location
    2p16.1; chr2:54723499-54972025 (+)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    4 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    3
  • GO References
    2
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

No experimental evidence to support Biological Process annotation, following literature review. See J:73796.
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    827
  • Tissues
    14
  • cDNA Data
    12
  • Literature Summary
    1
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000044072 Ensembl Gene Model | MGI Sequence Detail 282986 C57BL/6J ±  kb
transcript ENSMUST00000058902 Ensembl | MGI Sequence Detail 8083 Not Applicable  
polypeptide ENSMUSP00000051080 Ensembl | MGI Sequence Detail 1958 Not Applicable  
For the selected sequence
Protein
Information
less
  • UniProt
    3 Sequences
  • Protein Ontology
    PR:000007061 echinoderm microtubule-associated protein-like 6
    (term hierarchy)
  • InterPro Domains
    IPR024977 Anaphase-promoting complex subunit 4-like, WD40 domain
    IPR005108 HELP motif
    IPR011047 Quinoprotein alcohol dehydrogenase-like superfamily
    IPR001680 WD40 repeat
    IPR036322 WD40-repeat-containing domain superfamily
    IPR015943 WD40/YVTN repeat-like-containing domain superfamily
    IPR050630 WD repeat Echinoderm Microtubule-associated Protein-like
  • GlyGen
    Q5SQM0 1 site, 1 N-linked glycan (1 site)
Molecular
Reagents
less
  • All nucleic 12
    cDNA 12

    Microarray probesets 3
Other
Accession IDs
less
MGI:1920361
References
more
  • Summaries
    All 23
    Developmental Gene Expression 1
    Gene Ontology 2
    Phenotypes 4
  • Earliest
    J:137335 Roderick TH, Chromosomal inversions in studies of mammalian mutagenesis. Genetics. 1979 May;92(1 Pt 1 Suppl):s121-6
  • Latest
    J:153498 Diez-Roux G, et al., A high-resolution anatomical atlas of the transcriptome in the mouse embryo. PLoS Biol. 2011;9(1):e1000582
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
11/12/2024
MGI 6.24 		The Jackson Laboratory