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Tmcc3 Gene Detail
Summary
  • Symbol
    Tmcc3
  • Name
    transmembrane and coiled coil domains 3
  • Synonyms
    A230066D03Rik, C630016B22Rik, LOC380656
  • Feature Type
    protein coding gene
  • IDs
    MGI:2442900
    NCBI Gene: 319880
  • Alliance
    gene page
  • Transcription Start Sites
    33 TSS
Location &
Maps
more
  • Sequence Map
    Chr10:94147811-94426818 bp, + strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 10, 48.88 cM
  • Mapping Data
    3 experiments
Strain
Comparison
more
  • SNPs within 2kb
    8467 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_2442900
 protein coding gene Chr10:94147544-94426818 (+)
129S1/SvImJ MGP_129S1SvImJ_G0017664
 protein coding gene Chr10:95791986-96074092 (+)
A/J MGP_AJ_G0017643
 protein coding gene Chr10:92423645-92701859 (+)
AKR/J MGP_AKRJ_G0017601
 protein coding gene Chr10:95067492-95353219 (+)
BALB/cJ MGP_BALBcJ_G0017606
 protein coding gene Chr10:92706253-92980713 (+)
C3H/HeJ MGP_C3HHeJ_G0017429
 protein coding gene Chr10:95067141-95357808 (+)
C57BL/6NJ MGP_C57BL6NJ_G0018063
 protein coding gene Chr10:98965423-99265300 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0015744
 protein coding gene Chr10:88008617-88278435 (+)
CAST/EiJ MGP_CASTEiJ_G0016994
 protein coding gene Chr10:95079147-95372946 (+)
CBA/J MGP_CBAJ_G0017398
 protein coding gene Chr10:103052716-103374299 (+)
DBA/2J MGP_DBA2J_G0017504
 protein coding gene Chr10:91523807-91809014 (+)
FVB/NJ MGP_FVBNJ_G0017496
 protein coding gene Chr10:90757555-91039878 (+)
LP/J MGP_LPJ_G0017578
 protein coding gene Chr10:96400643-96694495 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0017527
 protein coding gene Chr10:104289202-104577777 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0018100
 protein coding gene Chr10:94975969-95265878 (+)
PWK/PhJ MGP_PWKPhJ_G0016775
 protein coding gene Chr10:91623235-91900336 (+)
SPRET/EiJ MGP_SPRETEiJ_G0016563
 protein coding gene Chr10:93784399-94137405 (+)
WSB/EiJ MGP_WSBEiJ_G0017053
 protein coding gene Chr10:94942905-95239253 (+)



Homology
more
  • Human Ortholog
    TMCC3, transmembrane and coiled-coil domain family 3
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    TMCC3, transmembrane and coiled-coil domain family 3
  • Links
    NCBI Gene ID: 57458
    neXtProt AC: NX_Q9ULS5
    UniProt: Q9ULS5

  • Chr Location
    12q22; chr12:94567122-94650557 (-)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    13 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    5
  • GO References
    3
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

No experimental evidence to support Biological Process annotation, following literature review. See J:73796.
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    805
  • Tissues
    63
  • cDNA Data
    73
  • Literature Summary
    5
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000020023 Ensembl Gene Model | MGI Sequence Detail 279008 C57BL/6J ±  kb
transcript ENSMUST00000065060 Ensembl | MGI Sequence Detail 5530 Not Applicable  
polypeptide ENSMUSP00000063264 Ensembl | MGI Sequence Detail 477 Not Applicable  
For the selected sequence
Protein
Information
less
  • UniProt
    6 Sequences
  • Protein Ontology
    PR:000030359 transmembrane and coiled-coil domain protein 3
    (term hierarchy)
  • InterPro Domains
    IPR019394 Testis-specific protein TEX28/transmembrane and coiled-coil domains protein
Molecular
Reagents
less
  • All nucleic 74
    cDNA 73
    Other 1

    Microarray probesets 9
Other
Accession IDs
less
MGI:2143840, MGI:2143949, MGI:2686402
References
more
  • Summaries
    All 42
    Developmental Gene Expression 5
    Gene Ontology 3
    Phenotypes 13
  • Earliest
    J:137335 Roderick TH, Chromosomal inversions in studies of mammalian mutagenesis. Genetics. 1979 May;92(1 Pt 1 Suppl):s121-6
  • Latest
    J:345621 Adams DJ, et al., Genetic determinants of micronucleus formation in vivo. Nature. 2024 Mar;627(8002):130-136
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
12/10/2024
MGI 6.24 		The Jackson Laboratory