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Vwc2 Gene Detail
Summary
  • Symbol
    Vwc2
  • Name
    von Willebrand factor C domain containing 2
  • Synonyms
    A930041G11Rik, Brorin, cradin
  • Feature Type
    protein coding gene
  • IDs
    MGI:2442987
    NCBI Gene: 319922
  • Alliance
    gene page
  • Transcription Start Sites
    3 TSS
Location &
Maps
more
  • Sequence Map
    Chr11:11064223-11218931 bp, + strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 11, 6.27 cM
  • Mapping Data
    1 experiment
Strain
Comparison
more
  • SNPs within 2kb
    4950 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_2442987
 protein coding gene Chr11:11063836-11219295 (+)
129S1/SvImJ MGP_129S1SvImJ_G0018042
 protein coding gene Chr11:8394219-8551149 (+)
A/J MGP_AJ_G0018015
 protein coding gene Chr11:8091672-8241241 (+)
AKR/J MGP_AKRJ_G0017979
 protein coding gene Chr11:8443708-8592931 (+)
BALB/cJ MGP_BALBcJ_G0017983
 protein coding gene Chr11:8118449-8268604 (+)
C3H/HeJ MGP_C3HHeJ_G0017796
 protein coding gene Chr11:8356124-8504866 (+)
C57BL/6NJ MGP_C57BL6NJ_G0018435
 protein coding gene Chr11:8682167-8838649 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0016093
 protein coding gene Chr11:7679417-7826013 (+)
CAST/EiJ MGP_CASTEiJ_G0017358
 protein coding gene Chr11:8370038-8523254 (+)
CBA/J MGP_CBAJ_G0017771
 protein coding gene Chr11:9300525-9454360 (+)
DBA/2J MGP_DBA2J_G0017881
 protein coding gene Chr11:8041411-8189432 (+)
FVB/NJ MGP_FVBNJ_G0017873
 protein coding gene Chr11:7949385-8097725 (+)
LP/J MGP_LPJ_G0017952
 protein coding gene Chr11:8500340-8665653 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0017899
 protein coding gene Chr11:8989827-9148302 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0018475
 protein coding gene Chr11:8472258-8619185 (+)
PWK/PhJ MGP_PWKPhJ_G0017138
 protein coding gene Chr11:8076474-8227573 (+)
SPRET/EiJ MGP_SPRETEiJ_G0016935
 protein coding gene Chr11:8314158-8470749 (+)
WSB/EiJ MGP_WSBEiJ_G0017412
 protein coding gene Chr11:8241160-8385923 (+)



Homology
more
  • Human Ortholog
    VWC2, von Willebrand factor C domain containing 2
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    VWC2, von Willebrand factor C domain containing 2
  • Synonyms
    PSST739, UNQ739
  • Links
    NCBI Gene ID: 375567
    neXtProt AC: NX_Q2TAL6
    UniProt: Q2TAL6

  • Chr Location
    7p12.2; chr7:49773638-49922205 (+)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    7 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    17
  • GO References
    5
Molecular Function

No experimental evidence to support Molecular Function annotation, following literature review. See J:73796.
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    760
  • Tissues
    33
  • cDNA Data
    7
  • Literature Summary
    5
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000050830 Ensembl Gene Model | MGI Sequence Detail 154709 C57BL/6J ±  kb
transcript ENSMUST00000056344 Ensembl | MGI Sequence Detail 1350 Not Applicable  
polypeptide ENSMUSP00000049692 Ensembl | MGI Sequence Detail 324 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 10
    cDNA 7
    Primer pair 2
    Other 1

    Microarray probesets 3
References
more
  • Summaries
    All 29
    Developmental Gene Expression 5
    Gene Ontology 5
    Phenotypes 7
  • Earliest
    J:80000 The FANTOM Consortium and The RIKEN Genome Exploration Research Group Phase I & II Team, Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs. Nature. 2002;420:563-573
  • Latest
    J:342640 Sampath Kumar A, et al., Spatiotemporal transcriptomic maps of whole mouse embryos at the onset of organogenesis. Nat Genet. 2023 Jul;55(7):1176-1185
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
12/10/2024
MGI 6.24 		The Jackson Laboratory