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Trappc8 Gene Detail
Summary
  • Symbol
    Trappc8
  • Name
    trafficking protein particle complex 8
  • Synonyms
    5033403J15Rik, D030074E01Rik, Trs85
  • Feature Type
    protein coding gene
  • IDs
    MGI:2443008
    NCBI Gene: 75964
  • Alliance
    gene page
  • Transcription Start Sites
    3 TSS
Location &
Maps
more
  • Sequence Map
    Chr18:20950280-21029150 bp, - strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 18, 11.53 cM
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    1554 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_2443008
 protein coding gene Chr18:20950268-21033851 (-)
129S1/SvImJ MGP_129S1SvImJ_G0024184
 protein coding gene Chr18:18411287-18497677 (-)
A/J MGP_AJ_G0024148
 protein coding gene Chr18:17944814-18025232 (-)
AKR/J MGP_AKRJ_G0024117
 protein coding gene Chr18:18486090-18567257 (-)
BALB/cJ MGP_BALBcJ_G0024148
 protein coding gene Chr18:17960721-18041293 (-)
C3H/HeJ MGP_C3HHeJ_G0023916
 protein coding gene Chr18:18427347-18509863 (-)
C57BL/6NJ MGP_C57BL6NJ_G0024590
 protein coding gene Chr18:19302567-19391016 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0022032
 protein coding gene Chr18:17041531-17124296 (-)
CAST/EiJ MGP_CASTEiJ_G0023389
 protein coding gene Chr18:18209624-18289550 (-)
CBA/J MGP_CBAJ_G0023884
 protein coding gene Chr18:19790060-19876422 (-)
DBA/2J MGP_DBA2J_G0024016
 protein coding gene Chr18:17655161-17734403 (-)
FVB/NJ MGP_FVBNJ_G0023982
 protein coding gene Chr18:17435850-17514981 (-)
LP/J MGP_LPJ_G0024097
 protein coding gene Chr18:18562771-18642707 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0024010
 protein coding gene Chr18:20695128-20781399 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0024638
 protein coding gene Chr18:18243119-18323711 (-)
PWK/PhJ MGP_PWKPhJ_G0023134
 protein coding gene Chr18:17756117-17836211 (-)
SPRET/EiJ MGP_SPRETEiJ_G0022943
 protein coding gene Chr18:18455627-18540828 (-)
WSB/EiJ MGP_WSBEiJ_G0023454
 protein coding gene Chr18:18177450-18258808 (-)



Homology
more
  • Human Ortholog
    TRAPPC8, trafficking protein particle complex subunit 8
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    TRAPPC8, trafficking protein particle complex subunit 8
  • Synonyms
    GSG1, HsT2706, KIAA1012, TRS85
  • Links
    NCBI Gene ID: 22878
    neXtProt AC: NX_Q9Y2L5
    UniProt: Q9Y2L5

  • Chr Location
    18q12.1; chr18:31829197-31953136 (-)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    6 phenotypes from 1 allele in 1 genetic background
    8 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    3
  • GO References
    2
Molecular Function

No experimental evidence to support Molecular Function annotation, following literature review. See J:73796.
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    706
  • cDNA Data
    81
  • Comparison Matrix
    Gene Expression + Phenotype
    • Sequences &
    Gene Models
    less
    Representative SequencesLengthStrain/SpeciesFlank
    genomic ENSMUSG00000033382 Ensembl Gene Model | MGI Sequence Detail 78871 C57BL/6J ±  kb
    transcript ENSMUST00000225661 Ensembl | MGI Sequence Detail 5194 Not Applicable  
    polypeptide ENSMUSP00000153183 Ensembl | MGI Sequence Detail 1437 Not Applicable  
    For the selected sequence
    Protein
    Information
    less
    • UniProt
      9 Sequences
    • InterPro Domains
      IPR011990 Tetratricopeptide-like helical domain superfamily
      IPR024420 TRAPP III complex, Trs85
    Molecular
    Reagents
    less
    • All nucleic 81
      cDNA 81

      Microarray probesets 3
    Other
    Accession IDs
    less
    MGI:1923214, MGI:2147268
    References
    more
    • Summaries
      All 30
      Gene Ontology 2
      Phenotypes 8
    • Earliest
      J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
    • Latest
      J:320033 Kim JJ, et al., TRAPP Complexes in Secretion and Autophagy. Front Cell Dev Biol. 2016;4:20
    Contributing Projects:
    Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
    Citing These Resources
    Funding Information
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    Send questions and comments to User Support.     		last database update
    12/10/2024
    MGI 6.24     		The Jackson Laboratory