Ubxn10 MGI Mouse Gene Detail - MGI:2443123

Symbol

Ubxn10
Name

UBX domain protein 10
Synonyms

5730509E04Rik, Ubxd3

Feature Type

protein coding gene
IDs

MGI:2443123
NCBI Gene: 212190
Alliance

gene page
Transcription Start Sites

2 TSS

Sequence Map

Chr4:138437148-138464478 bp, - strand
From Ensembl annotation of GRCm39
View this region in JBrowse
Genome Browsers

Ensembl | UCSC | NCBI

Genetic Map

Chromosome 4, 70.53 cM
Mapping Data

1 experiment

SNPs within 2kb

939 from dbSNP Build 142
Strain Annotations

18

For selected strains:

Strain	Gene Model ID	Feature Type	Coordinates
C57BL/6J	MGI_C57BL6J_2443123	protein coding gene	Chr4:138437148-138465749 (-)
129S1/SvImJ	MGP_129S1SvImJ_G0029000	protein coding gene	Chr4:141488864-141522071 (-)
A/J	MGP_AJ_G0028959	protein coding gene	Chr4:135417570-135445291 (-)
AKR/J	MGP_AKRJ_G0028911	protein coding gene	Chr4:139294421-139321423 (-)
BALB/cJ	MGP_BALBcJ_G0028983	protein coding gene	Chr4:136092911-136120532 (-)
C3H/HeJ	MGP_C3HHeJ_G0028697	protein coding gene	Chr4:139667505-139694511 (-)
C57BL/6NJ	MGP_C57BL6NJ_G0029424	protein coding gene	Chr4:146494650-146522680 (-)
CAROLI/EiJ	MGP_CAROLIEiJ_G0026695	protein coding gene	Chr4:128398765-128426507 (-)
CAST/EiJ	MGP_CASTEiJ_G0028129	protein coding gene	Chr4:137834945-137864901 (-)
CBA/J	MGP_CBAJ_G0028662	protein coding gene	Chr4:150714515-150741518 (-)
DBA/2J	MGP_DBA2J_G0028811	protein coding gene	Chr4:135800780-135827767 (-)
FVB/NJ	MGP_FVBNJ_G0028778	protein coding gene	Chr4:134825803-134852959 (-)
LP/J	MGP_LPJ_G0028910	protein coding gene	Chr4:141567035-141596736 (-)
NOD/ShiLtJ	MGP_NODShiLtJ_G0028804	protein coding gene	Chr4:154674028-154704809 (-)
NZO/HlLtJ	MGP_NZOHlLtJ_G0029462	protein coding gene	Chr4:139823980-139853550 (-)
PWK/PhJ	MGP_PWKPhJ_G0027850	protein coding gene	Chr4:132657527-132685289 (-)
SPRET/EiJ	MGP_SPRETEiJ_G0027675	protein coding gene	Chr4:135577590-135605995 (-)
WSB/EiJ	MGP_WSBEiJ_G0028207	protein coding gene	Chr4:140061940-140089448 (-)

Human Ortholog

UBXN10, UBX domain protein 10

Vertebrate Orthologs

3

Vertebrate Orthology Source

Alliance of Genome Resources

Human Ortholog

UBXN10, UBX domain protein 10
Synonyms

UBXD3
Links

HGNC:26354

NCBI Gene ID: 127733

neXtProt AC: NX_Q96LJ8

UniProt: Q96LJ8
Chr Location

1p36.12; chr1:20183331-20196050 (+) GRCh38

MGI Vertebrate Homology

Ubxn10 stringent orthology
1 human;1 mouse;1 rat;1 zebrafish
HCOP

vertebrate homology predictions: UBXN10
Gene Tree

Ubxn10

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Phenotype Summary

2 phenotypes from 1 allele in 1 genetic background
12 phenotype references

Phenotype Overview

Blue squares indicate phenotypes directly attributed to mutations/alleles of this gene.

adipose tissue	behavior/neurological	cardiovascular system	cellular	craniofacial	digestive/alimentary system	embryo	endocrine/exocrine glands	growth/size/body	hearing/vestibular/ear	hematopoietic system	homeostasis/metabolism	integument	immune system	limbs/digits/tail	liver/biliary system	mortality/aging	muscle	nervous system	pigmentation	renal/urinary system	reproductive system	respiratory system	skeleton	taste/olfaction	neoplasm	vision/eye

Click cells to view annotations.

All Mutations and Alleles

9
Chemically induced (other)

2
Gene trapped

2
Targeted

5
Genomic Mutations

3 involving Ubxn10
Incidental Mutations

Mutagenetix , APF , CvDC
Find Mice (IMSR)

18 strains or lines available
Comparison Matrix

Gene Expression + Phenotype

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All GO Annotations

9
GO References

3

Molecular Function

carbohydrate derivative binding	cytoskeletal protein binding	DNA binding	enzyme regulator	hydrolase	ligase	lipid binding	oxidoreductase	RNA binding	signaling receptor activity	signaling receptor binding	transcription	transferase	transporter

Biological Process

carbohydrate derivative metabolism	cell differentiation	cell population proliferation	cellular component organization	DNA-templated transcription	establishment of localization	homeostatic process	immune system process	lipid metabolic process	programmed cell death	protein metabolic process	response to stimulus	signaling	system development

Cellular Component

cell projection	cytoplasmic vesicle	cytoskeleton	cytosol	endoplasmic reticulum	endosome	extracellular region	Golgi apparatus	mitochondrion	membraneless organelle	nucleus	organelle envelope	organelle lumen	plasma membrane	protein-containing complex	synapse	vacuole

Click cells to view annotations.

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Expression Overview

GXD's primary emphasis is on endogenous gene expression during development. Click on grid cells to view annotations.

Blue cells = expressed in wild-type.
Gray triangles = other expression annotations only
(e.g. absence of expression or data from mutants).

early conceptus	embryo ectoderm	embryo endoderm	embryo mesoderm	embryo mesenchyme	extraembryonic component	alimentary system	auditory system	branchial arches	cardiovascular system	connective tissue	endocrine system	exocrine system	hemolymphoid system	integumental system	limbs	liver and biliary system	musculoskeletal system	nervous system	olfactory system	reproductive system	respiratory system	urinary system	visual system

Click cells to view annotations.

Assay Results

880
Tissues

19
cDNA Data

20
Literature Summary

2

Images

Tissue x Stage Matrix

Comparison Matrix

Gene Expression + Phenotype

Other Mouse Links

Allen Institute

GEO

Expression Atlas
Other Vertebrate Links

Xenbase ubxn10

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All Sequences

50
RefSeq

9
UniProt

2
CCDS

CCDS18830.1

Ensembl

ENSMUSG00000043621 (Evidence)
NCBI Gene

212190

			Length	Strain/Species	Flank
genomic	ENSMUSG00000043621	Ensembl Gene Model \| MGI Sequence Detail	27331	C57BL/6J	± kb
transcript	ENSMUST00000105810	Ensembl \| MGI Sequence Detail	3304	Not Applicable
polypeptide	ENSMUSP00000101436	Ensembl \| MGI Sequence Detail	277	Not Applicable

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UniProt

2 Sequences
Protein Ontology

PR:000031669 UBX domain-containing protein 10

(term hierarchy)
InterPro Domains

IPR029071 Ubiquitin-like domain superfamily

IPR001012 UBX domain

IPR050730 UBX domain-containing protein

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All nucleic 20

cDNA 20

Microarray probesets 4

Summaries

All 35

Developmental Gene Expression 2

Gene Ontology 3

Phenotypes 12
Earliest

J:80000 The FANTOM Consortium and The RIKEN Genome Exploration Research Group Phase I & II Team, Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs. Nature. 2002;420:563-573
Latest

J:345621 Adams DJ, et al., Genetic determinants of micronucleus formation in vivo. Nature. 2024 Mar;627(8002):130-136

TSS for Ubxn10:

(View these features in JBrowse)

Transcription Start Site	Location	Distance from Gene 5'-end
Tssr44174	Chr4:138452573-138452578 (-)	11,902 bp
Tssr44173	Chr4:138452521-138452569 (-)	11,933 bp

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources Funding Information Warranty Disclaimer, Privacy Notice, Licensing, & Copyright Send questions and comments to User Support.	last database update 12/10/2024 MGI 6.24