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Clvs2 Gene Detail
Summary
  • Symbol
    Clvs2
  • Name
    clavesin 2
  • Synonyms
    A330019N05Rik, Rlbp1l2
  • Feature Type
    protein coding gene
  • IDs
    MGI:2443223
    NCBI Gene: 215890
  • Alliance
  • Transcription Start Sites
    2 TSS
Location &
Maps
more
  • Sequence Map
    Chr10:33388282-33500680 bp, - strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
  • Genetic Map
    Chromosome 10, 18.62 cM
  • Mapping Data
    1 experiment
Strain
Comparison
more
  • SNPs within 2kb
    2961 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_2443223
protein coding gene Chr10:33388282-33500765 (-)
129S1/SvImJ MGP_129S1SvImJ_G0017126
protein coding gene Chr10:31821950-31938501 (-)
A/J MGP_AJ_G0017103
protein coding gene Chr10:30861777-30960091 (-)
AKR/J MGP_AKRJ_G0017063
protein coding gene Chr10:31345578-31455756 (-)
BALB/cJ MGP_BALBcJ_G0017066
protein coding gene Chr10:30936290-31043678 (-)
C3H/HeJ MGP_C3HHeJ_G0016886
protein coding gene Chr10:31630593-31754524 (-)
C57BL/6NJ MGP_C57BL6NJ_G0017524
protein coding gene Chr10:32759388-32862970 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0015221
protein coding gene Chr10:29317233-29418774 (-)
CAST/EiJ MGP_CASTEiJ_G0016465
protein coding gene Chr10:31748331-31846852 (-)
CBA/J MGP_CBAJ_G0016860
protein coding gene Chr10:34349705-34455912 (-)
DBA/2J MGP_DBA2J_G0016965
protein coding gene Chr10:30559639-30677651 (-)
FVB/NJ MGP_FVBNJ_G0016960
protein coding gene Chr10:30102461-30214673 (-)
LP/J MGP_LPJ_G0017042
protein coding gene Chr10:31809686-31933479 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0016990
protein coding gene Chr10:34767038-34906615 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0017560
protein coding gene Chr10:31292330-31419443 (-)
PWK/PhJ MGP_PWKPhJ_G0016247
protein coding gene Chr10:30342223-30440552 (-)
SPRET/EiJ MGP_SPRETEiJ_G0016030
protein coding gene Chr10:31207367-31312033 (-)
WSB/EiJ MGP_WSBEiJ_G0016528
protein coding gene Chr10:31521158-31639153 (-)



Homology
more
  • Human Ortholog
    CLVS2, clavesin 2
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    CLVS2, clavesin 2
  • Synonyms
    bA160A10.4, C6orf212, C6orf213, RLBP1L2
  • Links
    NCBI Gene ID: 134829
    neXtProt AC: NX_Q5SYC1
    UniProt: Q5SYC1

  • Chr Location
    6q22.31; chr6:122996235-123072925 (+)  GRCh38

Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    9 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
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Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic 215890 NCBI Gene Model | MGI Sequence Detail 112399 C57BL/6J ±  kb
transcript NM_175448 RefSeq | MGI Sequence Detail 2632 C57BL/6  
polypeptide Q8BG92 UniProt | EBI | MGI Sequence Detail 327 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 14
    cDNA 13
    Other 1

    Microarray probesets 3
References
more
  • Summaries
    All 31
    Developmental Gene Expression 1
    Gene Ontology 5
    Phenotypes 9
  • Earliest
    J:109968 Roderick TH, et al., Nineteen paracentric chromosomal inversions in mice. Genetics. 1974 Jan;76(1):109-17
  • Latest
    J:279375 Fritz KR, et al., Cdc42 activation by endothelin regulates neural crest cell migration in the cardiac outflow tract. Dev Dyn. 2019 Sep;248(9):795-812

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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last database update
12/10/2024
MGI 6.24
The Jackson Laboratory