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Acad12 Gene Detail
Summary
  • Symbol
    Acad12
  • Name
    acyl-Coenzyme A dehydrogenase family, member 12
  • Synonyms
    9330129D05Rik
  • Feature Type
    protein coding gene
  • IDs
    MGI:2443320
    NCBI Gene: 338350
  • Alliance
    gene page
  • Transcription Start Sites
    2 TSS
Location &
Maps
more
  • Sequence Map
    Chr5:121736340-121757001 bp, - strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 5, 61.87 cM
  • Mapping Data
    1 experiment
Strain
Comparison
more
  • SNPs within 2kb
    851 from dbSNP Build 142
  • Strain Annotations
    14
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_2443320
 protein coding gene Chr5:121734838-121757001 (-)
129S1/SvImJ MGP_129S1SvImJ_G0030034
 protein coding gene Chr5:125101176-125130668 (-)
A/J MGP_AJ_G0029999
 protein coding gene Chr5:119951168-120005596 (-)
AKR/J MGP_AKRJ_G0029935
 protein coding gene Chr5:123824394-123825523 (-)
BALB/cJ no annotation
C3H/HeJ no annotation
C57BL/6NJ MGP_C57BL6NJ_G0030463
 protein coding gene Chr5:129856876-129925344 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0027689
 protein coding gene Chr5:114625534-114683983 (-)
CAST/EiJ MGP_CASTEiJ_G0029136
 protein coding gene Chr5:123510564-123537324 (-)
CBA/J MGP_CBAJ_G0029697
 protein coding gene Chr5:134975972-134977046 (-)
DBA/2J MGP_DBA2J_G0029847
 protein coding gene Chr5:120009922-120044124 (-)
FVB/NJ no annotation
LP/J MGP_LPJ_G0029936
 protein coding gene Chr5:125615404-125655595 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0029834
 protein coding gene Chr5:138812816-138888314 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0030504
 protein coding gene Chr5:123350445-123389523 (-)
PWK/PhJ MGP_PWKPhJ_G0028850
 protein coding gene Chr5:118784947-118816110 (-)
SPRET/EiJ MGP_SPRETEiJ_G0028687
 protein coding gene Chr5:121095489-121147564 (-)
WSB/EiJ no annotation



Homology
more
  • Human Ortholog
    ACAD10, acyl-CoA dehydrogenase family member 10
  • Vertebrate Orthologs
    2
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    ACAD10, acyl-CoA dehydrogenase family member 10
  • Links
    NCBI Gene ID: 80724
    neXtProt AC: NX_Q6JQN1
    UniProt: Q6JQN1

  • Chr Location
    12q24.12
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    1 phenotype from 1 allele in 1 genetic background
    15 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    4
  • GO References
    2
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    706
  • cDNA Data
    9
  • Comparison Matrix
    Gene Expression + Phenotype
    • Sequences &
    Gene Models
    less
    Representative SequencesLengthStrain/SpeciesFlank
    genomic 338350 NCBI Gene Model | MGI Sequence Detail 20662 C57BL/6J ±  kb
    transcript NM_178799 RefSeq | MGI Sequence Detail 2375 C57BL/6  
    polypeptide NP_848914 RefSeq | MGI Sequence Detail 555 C57BL/6  
    For the selected sequence
    Protein
    Information
    less
    • UniProt
      5 Sequences
    • InterPro Domains
      IPR050741 Acyl-CoA dehydrogenase
      IPR036250 Acyl-CoA dehydrogenase-like, C-terminal
      IPR009075 Acyl-CoA dehydrogenase/oxidase, C-terminal
      IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal
      IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain superfamily
      IPR037069 Acyl-CoA dehydrogenase/oxidase, N-terminal domain superfamily
      IPR006091 Acyl-CoA oxidase/dehydrogenase, middle domain
      IPR046373 Acyl-CoA oxidase/dehydrogenase, middle domain superfamily
    • GlyGen
      D3Z7X0 1 site, 1 O-linked glycan (1 site)
    Molecular
    Reagents
    less
    • All nucleic 9
      cDNA 9

      Microarray probesets 2
    References
    more
    • Summaries
      All 31
      Gene Ontology 2
      Phenotypes 15
    • Earliest
      J:134667 Roderick TH, et al., Two radiation-induced chromosomal inversions in mice (Mus musculus). Proc Natl Acad Sci U S A. 1970 Oct;67(2):961-7
    • Latest
      J:345621 Adams DJ, et al., Genetic determinants of micronucleus formation in vivo. Nature. 2024 Mar;627(8002):130-136
    Contributing Projects:
    Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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    Funding Information
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    12/10/2024
    MGI 6.24     		The Jackson Laboratory